Mitochondrial Translocase of the Outer Membrane Alterations May Underlie Dysfunctional Oxidative Phosphorylation in Alzheimer's Disease

by Chai, Yuek Ling, Xing, Huayang, Chong, Joyce R, Francis, Paul T, Ballard, Clive G, Chen, Christopher P, Lai, Mitchell KP
Published 2021

Sphingolipidomics analysis of large clinical cohorts. Part 1: Technical notes and practical considerations

by Chew, Wee Siong, Seow, Wei Lun, Chong, Joyce R, Lai, Mitchell KP, Torta, Federico, Wenk, Markus R, Herr, Deron R
Published 2020

Elevation of inactive cleaved annexin A1 in the neocortex is associated with amyloid, inflammatory and apoptotic markers in neurodegenerative dementias

by Chua, Xin Ying, Chong, Joyce R, Lee, Jasinda H, Ballard, Clive, Aarsland, Dag, Francis, Paul T, Cheng, Ai Ling, Lai, Mitchell KP
Published 2023

Sphingolipidomics analysis of large clinical cohorts. Part 2: Potential impact and applications

by Chong, Joyce R, Xiang, Ping, Wang, Wei, Hind, Tatsuma, Chew, Wee Siong, Ong, Wei-Yi, Lai, Mitchell KP, Herr, Deron R
Published 2021

Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer's disease: a focused review on recent advances

by Chong, Joyce R, Ashton, Nicholas J, Karikari, Thomas K, Tanaka, Tomotaka, Scholl, Michael, Zetterberg, Henrik, Blennow, Kaj, Chen, Christopher P, Lai, Mitchell KP
Published 2023

Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration

by Chai, Yuek Ling, Chong, Joyce R, Weng, Jiaju, Howlett, David, Halsey, Andrea, Lee, Jasinda H, Attems, Johannes, Aarsland, Dag, Francis, Paul T, Chet, Christopher P, Lai, Mitchell K
Published 2021

Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer's disease but not Lewy body dementias.

by Chai, Yuek Ling, Lee, Jasinda H, Chong, Joyce R, Ballard, Clive, Francis, Paul T, Kennedy, Brian K, Arumugam, Thiruma V, Chen, Christopher P, Aarsland, Dag, Lai, Mitchell KP
Published 2023

Plasma osteopontin as a biomarker of Alzheimer's disease and vascular cognitive impairment

by Chai, Yuek Ling, Chong, Joyce R, Raquib, Ainiah R, Xu, Xin, Hilal, Saima, Venketasubramanian, Narayanaswamy, Tan, Boon Yeow, Kumar, Alan P, Sethi, Gautam, Chen, Christopher P, Lai, Mitchell KP
Published 2021

Plasma P‐tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular di...

by Chong, Joyce R, Ashton, Nicholas J, Karikari, Thomas K, Tanaka, Tomotaka, Saridin, Francis N, Reilhac, Anthonin, Robins, Edward G, Nai, Ying-Hwey, Vrooman, Henri, Hilal, Saima, Zetterberg, Henrik, Blennow, Kaj, Lai, Mitchell KP, Chen, Christopher P
Published 2021

Immunomodulatory sphingosine-1-phosphates as plasma biomarkers of Alzheimer's disease and vascular cognitive impairment

by Chua, Xin Ying, Chai, Yuek Ling, Chew, Wee Siong, Chong, Joyce R, Ang, Hui Li, Xiang, Ping, Camara, Kaddy, Howell, Amy R, Torta, Federico, Wenk, Markus R, Hilal, Saima, Venketasubramanian, Narayanaswamy, Chen, Christopher P, Herr, Deron R, Lai, Mitchell KP
Published 2021