Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration

• Main Authors: Chai, Yuek Ling, Chong, Joyce R, Weng, Jiaju, Howlett, David, Halsey, Andrea, Lee, Jasinda H, Attems, Johannes, Aarsland, Dag, Francis, Paul T, Chet, Christopher P, Lai, Mitchell K
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Language: English
• Published: WILEY 2021
• Subjects: Science & Technology; Life Sciences & Biomedicine; Clinical Neurology; Neurosciences; Pathology; Neurosciences & Neurology; Alzheimer's disease; cathepsin D; Lewy body dementia; lysosome; neurofibrillary degeneration; AMYLOID PRECURSOR PROTEIN; A-BETA-DEPOSITION; LEWY BODIES; NEUROPATHOLOGIC ASSESSMENT; PARKINSON-DISEASE; ALPHA-SYNUCLEIN; PROCATHEPSIN-D; CELL-CYCLE; DEMENTIA; TAU
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/188360
• Institution: National University of Singapore

10.1111/bpa.12631