IRF-7 mediates type I IFN responses in endotoxin-challenged mice

by Sin, Wei-Xiang, Yeong, Joe Poh-Sheng, Lim, Thomas Jun Feng, Su, I-hsin, Connolly, John E., Chin, Keh-Chuang
Published 2020

Enhancing antigen cross-presentation in human monocyte-derived dendritic cells by recruiting the intracellular Fc receptor TRIM21

by Ng, Patricia M. L., Kaliaperumal, Nivashini, Lee, Chia Yin, Chin, Wen Jie, Tan, Hwee Ching, Au, Veonice B., Goh, Angeline X.-H., Tan, Qiao Wen, Yeo, Darren S. G., Connolly, John E., Wang, Cheng-I
Published 2019

Toll-Like Receptor 9 Deficiency Breaks Tolerance to RNA-Associated Antigens and Up-Regulates Toll-Like Receptor 7 Protein in Sle1 Mice

by Celhar, Teja, Yasuga, Hiroko, Lee, Hui Yin, Zharkova, Olga, Tripathi, Shubhita, Thornhill, Susannah I, Lu, Hao K, Au, Bijin, Lim, Lina HK, Thamboo, Thomas P, Akira, Shizuo, Wakeland, Edward K, Connolly, John E, Fairhurst, Anna-Marie
Published 2020

Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects

by He, Qianqian, Au, Bijin, Kulkarni, Madhura, Shen, Yang, Lim, Kah. J., Maimaiti, Jiamila, Wong, Cheng. Kit., Luijten, Monique Nicole Helena, Chong, Han Chung, Lim, Elaine H., Rancati, Giulia, Sinha, Indrajit, Fu, Zhiyan, Wang, Xiaomeng, Connolly, John. E., Crasta, Karen Carmelina
Published 2018

RNA sensing by conventional dendritic cells is central to the development of lupus nephritis

by Celhar, Teja, Hopkins, Richard, Thornhill, Susannah I., De Magalhaes, Raquel, Hwang, Sun-Hee, Lee, Hui-Yin, Yasuga, Hiroko, Jones, Leigh A., Casco, Jose, Lee, Bernett, Thamboo, Thomas P., Zhou, Xin J., Poidinger, Michael, Connolly, John E., Wakeland, Edward K., Fairhurst, Anna-Marie
Published 2015

Effective Killing of Acute Myeloid Leukemia by TIM-3 Targeted Chimeric Antigen Receptor T Cells

by Lee, Wen-Hsin Sandy, Ye, Zhiyong, Cheung, Alice MS, Goh, YP Sharon, Oh, Hsueh Ling Janice, Rajarethinam, Ravisankar, Yeo, Siok Ping, Soh, Mun Kuen, Li Chan, Esther Hian, Tan, Lip Kun, Tan, Soo-Yong, Chuah, Charles, Chng, Wee Joo, Connolly, John E, Wang, Cheng-I
Published 2021

A multicenter phase II randomized trial of durvalumab (MEDI-4736) versus physician's choice chemotherapy in recurrent ovarian clear cell adenocarcinoma (MOCCA)

by Ngoi, Natalie YL, Heong, Valerie, Ow, Samuel, Chay, Wen Yee, Kim, Hee Seung, Choi, Chel Hun, Goss, Geraldine, Goh, Jeffrey C, Tai, Bee Choo, Lim, Diana G, Kaliaperumal, Nivashini, Au, Veonice B, Connolly, John E, Kim, Jae-Weon, Friedlander, Michael, Kim, Kidong, Tan, David SP
Published 2020

TLR7 protein expression in mild and severe lupus-prone models is regulated in a leukocyte, genetic, and IRAK4 dependent manner

by Celhar, Teja, Lu, Hao Kim, Benso, Lia, Rakhilina, Larissa, Lee, Hui Yin, Tripathi, Shubhita, Zharkova, Olga, Ong, Wei Yee, Yasuga, Hiroko, Au, Bijin, Marlier, Damien, Lim, Lina Hsiu Kim, Thamboo, Thomas Paulraj, Mudgett, John S., Mackey, Matthew F., Zaller, Dennis M., Connolly, John E., Fairhurst, Anna-Marie
Published 2019

TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner

by Celhar, Teja, Lu, Hao Kim, Benso, Lia, Rakhilina, Larissa, Lee, Hui Yin, Tripathi, Shubhita, Zharkova, Olga, Ong, Wei Yee, Yasuga, Hiroko, Au, Bijin, Marlier, Damien, Lim, Lina Hsiu Kim, Thamboo, Thomas Paulraj, Mudgett, John S, Mackey, Matthew F, Zaller, Dennis M, Connolly, John E, Fairhurst, Anna-Marie
Published 2020

Autophagy governs protumorigenic effects of mitotic slippage-induced senescence

by Jakhar, Rekha, Luijten, Monique N. H., Wong, Alex X. F., Cheng, Bing, Guo, Ke, Neo, Suat P., Au, Bijin, Kulkarni, Madhura, Lim, Kah J., Maimaiti, Jiamila, Chong, Han Chung, Lim, Elaine H., Tan, Tee B. K., Ong, Kong W., Sim, Yirong, Wong, Jill S. L., Khoo, James B. K., Ho, Juliana T. S., Chua, Boon T., Sinha, Indrajit, Wang, Xiaomeng, Connolly, John E., Gunaratne, Jayantha, Crasta, Karen Carmelina
Published 2020

Immunological corollary of the pulmonary mycobiome in bronchiectasis : the CAMEB study

by Mac Aogáin, Micheál, Chandrasekaran, Ravishankar, Lim, Albert Yick Hou, Low, Teck Boon, Tan, Gan Liang, Hassan, Tidi, Ong, Thun How, Bertrand, Denis, Koh, Jia Yu, Lee, Zi Yang, Gwee, Xiao Wei, Martinus, Christopher, Matta, Sri Anusha, Chew, Fook Tim, Keir, Holly R., Abisheganaden, John Arputhan, Koh, Mariko Siyue, Nagarajan, Niranjan, Chalmers, James D., Ng, Amanda Hui Qi, Pang, Sze Lei, Sio, Yang Yie, Connolly, John E., Chotirmall, Sanjay Haresh
Published 2019

Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study

by Mac Aogain, Micheal, Chandrasekaran, Ravishankar, Lim, Albert Yick Hou, Low, Teck Boon, Tan, Gan Liang, Hassan, Tidi, Thun, How Ong, Ng, Amanda Hui Qi, Bertrand, Denis, Koh, Jia Yu, Pang, Sze Lei, Lee, Zi Yang, Gwee, Xiao Wei, Martinus, Christopher, Sio, Yang Yie, Matta, Sri Anusha, Chew, Fook Tim, Keir, Holly R, Connolly, John E, Abisheganaden, John Arputhan, Koh, Mariko Siyue, Nagarajan, Niranjan, Chalmers, James D, Chotirmall, Sanjay H
Published 2022

Platelet TLR7 is essential for the formation of platelet-neutrophil complexes and low-density neutrophils in lupus nephritis

by Tay, Sen Hee, Zharkova, Olga, Lee, Hui Yin, Toh, Michelle Min Xuan, Libau, Eshele Anak, Celhar, Teja, Narayanan, Sriram, Ahl, Patricia Jennifer, Ong, Wei Yee, Joseph, Craig, Lim, Jeffrey Chun Tatt, Wang, Lingzhi, Larbi, Anis, Liang, Shen, Lateef, Aisha, Akira, Shizuo, Ling, Lieng Hsi, Thamboo, Thomas Paulraj, Yeong, Joe Poh Seng, Lee, Bernett Teck Kwong, Edwards, Steven W, Wright, Helen L, MacAry, Paul Anthony, Connolly, John E, Fairhurst, Anna-Marie
Published 2024

Dendritic cell therapy with CD137L-DC-EBV-VAX in locally recurrent or metastatic nasopharyngeal carcinoma is safe and confers clinical benefit

by Nickles, Emily, Dharmadhikari, Bhushan, Li, Yating, Walsh, Robert J, Koh, Liang Piu, Poon, Michelle, Tan, Lip Kun, Wang, Ling-Zhi, Ang, Yvonne, Asokumaran, Yugarajah, Chong, Wan Qin, Huang, Yiqing, Loh, Kwok Seng, Tay, Joshua, Soo, Ross, Koh, Mickey, Ho, Liam Pock, Chan, Marieta, Niam, Madelaine, Soh, Melissa, Luah, Yen Hoon, Lim, Chwee Ming, Kaliaperumal, Nivashini, Au, Veonice B, Talib, Najwa Binte Said Nasir, Sng, Reina, Connolly, John E, Goh, Boon Cher, Schwarz, Herbert
Published 2023

Distinct "immunoallertypes" of disease and high frequencies of sensitization in non-cystic fibrosis bronchiectasis

by Mac Aogáin, Micheál, Tiew, Pei Yee, Lim, Albert Yick Hou, Low, Teck Boon, Tan, Gan Liang, Hassan, Tidi, Ong, Thun How, Pang, Sze Lei, Lee, Zi Yang, Gwee, Xiao Wei, Martinus, Christopher, Sio, Yang Yie, Matta, Sri Anusha, Ong, Tan Ching, Tiong, Yuen Seng, Wong, Kang Ning, Narayanan, Sriram, Au, Veonice Bijin, Marlier, Damien, Keir, Holly R., Tee, Augustine, Abisheganaden, John Arputhan, Koh, Mariko Siyue, Wang, De Yun, Connolly, John E., Chew, Fook Tim, Chalmers, James D., Chotirmall, Sanjay Haresh
Published 2020