Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis

by Yarmolinsky, James, Relton, Caroline L., Lophatananon, Artitaya, Muir, Kenneth, Menon, Usha, Gentry-Maharaj, Aleksandra, Walther, Axel, Zheng, Jie, Fasching, Peter, Zheng, Wei, Woo, Yin Ling, Park, Sue K., Kim, Byoung-Gie, Choi, Ji-Yeob, Park, Boyoung, Davey Smith, George, Martin, Richard M., Lewis, Sarah J.
Published 2019

Genome-wide association study reveals multiple loci associated with primary tooth development during infancy

by Demetris Pillas, Clive J. Hoggart, David M. Evans, Paul F. O'Reilly, Kirsi Sipilä, Raija Lähdesmäki, Iona Y. Millwood, Marika Kaakinen, Gopalakrishnan Netuveli, David Blane, Pimphen Charoen, Ulla Sovio, Anneli Pouta, Nelson Freimer, Anna Liisa Hartikainen, Jaana Laitinen, Sarianna Vaara, Beate Glaser, Peter Crawford, Nicholas J. Timpson, Susan M. Ring, Guohong Deng, Weihua Zhang, Mark I. McCarthy, Panos Deloukas, Leena Peltonen, Paul Elliott, Lachlan J.M. Coin, George Davey Smith, Marjo Riitta Jarvelin
Published 2018

Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: Programmatic implications for countries phas...

by Michele W. Tang, Soo Yon Rhee, Silvia Bertagnolio, Nathan Ford, Susan Holmes, Kim C. Sigaloff, Raph L. Hamers, Tobias F.Rinke De Wit, Herve J. Fleury, Phyllis J. Kanki, Kiat Ruxrungtham, Claudia A. Hawkins, Carole L. Wallis, Wendy Stevens, Gert U. Van Zyl, Weerawat Manosuthi, Mina C. Hosseinipour, Nicole Ngo-Giang-Huong, Laurent Belec, Martine Peeters, Avelin Aghokeng, Torsak Bunupuradah, Sherri Burda, Patricia Cane, Giulia Cappelli, Charlotte Charpentier, Anoumou Y. Dagnra, Alaka K. Deshpande, Ziad El-Katib, Susan H. Eshleman, Joseph Fokam, Jean Chrysostome Gody, David Katzenstein, Donato D. Koyalta, Johnstone J. Kumwenda, Marc Lallemant, Lutgarde Lynen, Vincent C. Marconi, Nicolas A. Margot, Sandrine Moussa, Thumbi Ndung'U, Phillipe N. Nyambi, Catherine Orrell, Jonathan M. Schapiro, Rob Schuurman, Sunee Sirivichayakul, Davey Smith, Maria Zolfo, Michael R. Jordan, Robert W. Shafer
Published 2018

Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: Programmatic implications for countries phas...

by Michele W. Tang, Soo Yon Rhee, Silvia Bertagnolio, Nathan Ford, Susan Holmes, Kim C. Sigaloff, Raph L. Hamers, Tobias F.Rinke De Wit, Herve J. Fleury, Phyllis J. Kanki, Kiat Ruxrungtham, Claudia A. Hawkins, Carole L. Wallis, Wendy Stevens, Gert U. Van Zyl, Weerawat Manosuthi, Mina C. Hosseinipour, Nicole Ngo-Giang-Huong, Laurent Belec, Martine Peeters, Avelin Aghokeng, Torsak Bunupuradah, Sherri Burda, Patricia Cane, Giulia Cappelli, Charlotte Charpentier, Anoumou Y. Dagnra, Alaka K. Deshpande, Ziad El-Katib, Susan H. Eshleman, Joseph Fokam, Jean Chrysostome Gody, David Katzenstein, Donato D. Koyalta, Johnstone J. Kumwenda, Marc Lallemant, Lutgarde Lynen, Vincent C. Marconi, Nicolas A. Margot, Sandrine Moussa, Thumbi Ndung'U, Phillipe N. Nyambi, Catherine Orrell, Jonathan M. Schapiro, Rob Schuurman, Sunee Sirivichayakul, Davey Smith, Maria Zolfo, Michael R. Jordan, Robert W. Shafer
Published 2018

Whole-genome sequence-based analysis of thyroid function

by Peter N. Taylor, Eleonora Porcu, Shelby Chew, Purdey J. Campbell, Michela Traglia, Suzanne J. Brown, Benjamin H. Mullin, Hashem A. Shihab, Josine Min, Klaudia Walter, Yasin Memari, Jie Huang, Michael R. Barnes, John P. Beilby, Pimphen Charoen, Petr Danecek, Frank Dudbridge, Vincenzo Forgetta, Celia Greenwood, Elin Grundberg, Andrew D. Johnson, Jennie Hui, Ee M. Lim, Shane McCarthy, Dawn Muddyman, Vijay Panicker, John R.B. Perry, Jordana T. Bell, Wei Yuan, Caroline Relton, Tom Gaunt, David Schlessinger, Goncalo Abecasis, Francesco Cucca, Gabriela L. Surdulescu, Wolfram Woltersdorf, Eleftheria Zeggini, Hou Feng Zheng, Daniela Toniolo, Colin M. Dayan, Silvia Naitza, John P. Walsh, Tim Spector, George Davey Smith, Richard Durbin, J. Brent Richards, Serena Sanna, Nicole Soranzo, Nicholas J. Timpson, Scott G. Wilson, Saeed Al Turki, Carl Anderson, Richard Anney, Dinu Antony, Maria Soler Artigas, Muhammad Ayub, Senduran Balasubramaniam, Jeffrey C. Barrett, Inês Barroso, Phil Beales, Jamie Bentham, Shoumo Bhattacharya, Ewan Birney, Douglas Blackwood, Martin Bobrow, Elena Bochukova, Patrick Bolton, Rebecca Bounds, Chris Boustred, Gerome Breen, Mattia Calissano, Keren Carss, Krishna Chatterjee, Lu Chen, Antonio Ciampi
Published 2018

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

by Symen Ligthart, Ahmad Vaez, Urmo Võsa, Maria G. Stathopoulou, Paul S. de Vries, Bram P. Prins, Peter J. Van der Most, Toshiko Tanaka, Elnaz Naderi, Lynda M. Rose, Ying Wu, Robert Karlsson, Maja Barbalic, Honghuang Lin, René Pool, Gu Zhu, Aurélien Macé, Carlo Sidore, Stella Trompet, Massimo Mangino, Maria Sabater-Lleal, John P. Kemp, Ali Abbasi, Tim Kacprowski, Niek Verweij, Albert V. Smith, Tao Huang, Carola Marzi, Mary F. Feitosa, Kurt K. Lohman, Marcus E. Kleber, Yuri Milaneschi, Christian Mueller, Mahmudul Huq, Efthymia Vlachopoulou, Leo Pekka Lyytikäinen, Christopher Oldmeadow, Joris Deelen, Markus Perola, Jing Hua Zhao, Bjarke Feenstra, Behrooz Z. Alizadeh, H. Marike Boezen, Lude Franke, Pim van der Harst, Gerjan Navis, Marianne Rots, Harold Snieder, Morris Swertz, Bruce H.R. Wolffenbuttel, Cisca Wijmenga, Marzyeh Amini, Emelia Benjamin, Daniel I. Chasman, Abbas Dehghan, Tarunveer Singh Ahluwalia, James Meigs, Russell Tracy, Josh Bis, Gudny Eiriksdottir, Nathan Pankratz, Myron Gross, Alex Rainer, James G. Wilson, Bruce M. Psaty, Josee Dupuis, Bram Prins, Urmo Vaso, Maria Stathopoulou, Terho Lehtimaki, Wolfgang Koenig, Yalda Jamshidi, Sophie Siest, Andre G. Uitterlinden, Mohammadreza Abdollahi, Renate Schnabel, Ursula M. Schick, Ilja M. Nolte, Aldi Kraja, Yi Hsiang Hsu, Daniel S. Tylee, Alyson Zwicker, Rudolf Uher, George Davey-Smith, Alanna C. Morrison, Andrew Hicks, Cornelia M. van Duijn, Cavin Ward-Caviness, Eric Boerwinkle, J. Rotter, Ken Rice, Leslie Lange, Markus Perola, Eco de Geus, Andrew P. Morris
Published 2019

The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study

by Johansson, M., Carreras-Torres, R., Scelo, G., Purdue, M.P., Mariosa, D., Muller, D.C., Timpson, N.J., Haycock, P.C., Brown, K.M., Wang, Z., Ye, Y., Hofmann, J.N., Foll, M., Gaborieau, V., Machiela, M.J., Colli, L.M., Li, P., Garnier, J.-G., Blanche, H., Boland, A., Burdette, L., Prokhortchouk, E., Skryabin, K.G., Yeager, M., Radojevic-Skodric, S., Ognjanovic, S., Foretova, L., Holcatova, I., Janout, V., Mates, D., Mukeriya, A., Rascu, S., Zaridze, D., Bencko, V., Cybulski, C., Fabianova, E., Jinga, V., Lissowska, J., Lubinski, J., Navratilova, M., Rudnai, P., Benhamou, S., Cancel-Tassin, G., Cussenot, O., Weiderpass, E., Ljungberg, B., Tumkur Sitaram, R., Häggström, C., Bruinsma, F., Jordan, S.J., Severi, G., Winship, I., Hveem, K., Vatten, L.J., Fletcher, T., Larsson, S.C., Wolk, A., Banks, R.E., Selby, P.J., Easton, D.F., Andreotti, G., Beane Freeman, L.E., Koutros, S., Männistö, S., Weinstein, S., Clark, P.E., Edwards, T.L., Lipworth, L., Gapstur, S.M., Stevens, V.L., Carol, H., Freedman, M.L., Pomerantz, M.M., Cho, E., Wilson, K.M., Gaziano, J.M., Sesso, H.D., Freedman, N.D., Parker, A.S., Eckel-Passow, J.E., Huang, W.-Y., Kahnoski, R.J., Lane, B.R., Noyes, S.L., Petillo, D., Teh, B.T., Peters, U., White, E., Anderson, G.L., Johnson, L., Luo, J., Buring, J., Lee, I.-M., Chow, W.-H., Moore, L.E., Eisen, T., Henrion, M., Larkin, J., Barman, P., Leibovich, B.C., Choueiri, T.K., Lathrop, G.M., Deleuze, J.-F., Gunter, M., McKay, J.D., Wu, X., Houlston, R.S., Chanock, S.J., Relton, C., Richards, J.B., Martin, R.M., Davey Smith, G., Brennan, P.
Published 2021

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

by Fall T., Hägg S., Mägi R., Ploner A., Fischer K., Horikoshi M., Sarin A.-P., Thorleifsson G., Ladenvall C., Kals M., Kuningas M., Draisma H.H.M., Ried J.S., van Zuydam N.R., Huikari V., Mangino M., Sonestedt E., Benyamin B., Nelson C.P., Rivera N.V., Kristiansson K., Shen H.-y., Havulinna A.S., Dehghan A., Donnelly L.A., Kaakinen M., Nuotio M.-L., Robertson N., de Bruijn R.F.A.G., Ikram M.A., Amin N., Balmforth A.J., Braund P.S., Doney A.S.F., Döring A., Elliott P., Esko T., Franco O.H., Gretarsdottir S., Hartikainen A.-L., Heikkilä K., Herzig K.-H., Holm H., Hottenga J.J., Hyppönen E., Illig T., Isaacs A., Isomaa B., Karssen L.C., Kettunen J., Koenig W., Kuulasmaa K., Laatikainen T., Laitinen J., Lindgren C., Lyssenko V., Läärä E., Rayner N.W., Männistö S., Pouta A., Rathmann W., Rivadeneira F., Ruokonen A., Savolainen M.J., Sijbrands E.J.G., Small K.S., Smit J.H., Steinthorsdottir V., Syvänen A.-C., Taanila A., Tobin M.D., Uitterlinden A.G., Willems S.M., Willemsen G., Witteman J., Perola M., Evans A., Ferrières J., Virtamo J., Kee F., Tregouet D.-A., Arveiler D., Amouyel P., Ferrario M.M., Brambilla P., Hall A.S., Heath A.C., Madden P.A.F., Martin N.G., Montgomery G.W., Whitfield J.B., Jula A., Knekt P., Oostra B., van Duijn C.M., Penninx B.W.J.H., Davey Smith G., Kaprio J., Samani N.J., Gieger C., Peters A., Wichmann H.-E., Boomsma D.I., de Geus E.J.C., Tuomi T.M., Power C., Hammond C.J., Spector T.D., Lind L., Orho-Melander M., Palmer C.N.A., Morris A.D., Groop L., Järvelin M.-R., Salomaa V., Vartiainen E., Hofman A., Ripatti S., Metspalu A., Thorsteinsdottir U., Stefansson K., Pedersen N.L., McCarthy M.I., Ingelsson E., Prokopenko I.
Published 2019

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

by Huang, T., Wang, T., Zheng, Y., Ellervik, C., Li, X., Gao, M., Fang, Z., Chai, J.-F., Ahluwalia, T.V.S., Wang, Y., Voortman, T., Noordam, R., Frazier-Wood, A., Scholz, M., Sonestedt, E., Akiyama, M., Dorajoo, R., Zhou, A., Kilpeläinen, T.O., Kleber, M.E., Crozier, S.R., Godfrey, K.M., Lemaitre, R., Felix, J.F., Shi, Y., Gupta, P., Khor, C.-C., Lehtimäki, T., Wang, C.A., Tiesler, C.M.T., Thiering, E., Standl, M., Rzehak, P., Marouli, E., He, M., Lecoeur, C., Corella, D., Lai, C.-Q., Moreno, L.A., Pitkänen, N., Boreham, C.A., Zhang, T., Saw, S.M., Ridker, P.M., Graff, M., van Rooij, F.J.A., Uitterlinden, A.G., Hofman, A., van Heemst, D., Rosendaal, F.R., de Mutsert, R., Burkhardt, R., Schulz, C.-A., Ericson, U., Kamatani, Y., Yuan, J.-M., Power, C., Hansen, T., Sørensen, T.I.A., Tjønneland, A., Overvad, K., Delgado, G., Cooper, C., Djousse, L., Rivadeneira, F., Jameson, K., Zhao, W., Liu, J., Lee, N.R., Raitakari, O., Kähönen, M., Viikari, J., Grote, V., Langhendries, J.-P., Koletzko, B., Escribano, J., Verduci, E., Dedoussis, G., Yu, C., Tham, Y.C., Lim, B., Lim, S.H., Froguel, P., Balkau, B., Fink, N.R., Vinding, R.K., Sevelsted, A., Bisgaard, H., Coltell, O., Dallongeville, J., Gottrand, F., Pahkala, K., Niinikoski, H., Hyppönen, E., Pedersen, O., März, W., Inskip, H., Jaddoe, V.W.V., Dennison, E., Wong, T.Y., Sabanayagam, C., Tai, E.-S., Mohlke, K.L., Mackey, D.A., Gruszfeld, D., Deloukas, P., Tucker, K.L., Fumeron, F., Bønnelykke, K., Rossing, P., Estruch, R., Ordovas, J.M., Arnett, D.K., Meirhaeghe, A., Amouyel, P., Cheng, C.-Y., Sim, X., Teo, Y.Y., van Dam, R.M., Koh, W.-P., Orho-Melander, M., Loeffler, M., Kubo, M., Thiery, J., Mook-Kanamori, D.O., Mozaffarian, D., Psaty, B.M., Franco, O.H., Wu, T., North, K.E., Davey Smith, G., Chavarro, J.E., Chasman, D.I., Qi, L., BIRTH-GENE (BIG) Study Working Group.
Published 2022

A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension

by Huan T., Esko T., Peters M.J., Pilling L.C., Schramm K., Schurmann C., Chen B.H., Liu C., Joehanes R., Johnson A.D., Yao C., Ying S.-X., Courchesne P., Milani L., Raghavachari N., Wang R., Liu P., Reinmaa E., Dehghan A., Hofman A., Uitterlinden A.G., Hernandez D.G., Bandinelli S., Singleton A., Melzer D., Metspalu A., Carstensen M., Grallert H., Herder C., Meitinger T., Peters A., Roden M., Waldenberger M., Dörr M., Felix S.B., Zeller T., International Consortium for Blood Pressure GWAS (ICBP), Vasan R., O'Donnell C.J., Munson P.J., Yang X., Prokisch H., Völker U., van Meurs J.B.J., Ferrucci L., Levy D., Ehret G.B., Munroe P.B., Rice K.M., Bochud M., Johnson A.D., Chasman D.I., Smith A.V., Tobin M.D., Verwoert G.C., Hwang S.-J., Pihur V., Vollenweider P., O’Reilly P.F., Amin N., Bragg-Gresham J.L., Teumer A., Glazer N.L., Launer L., Zhao J.H., Aulchenko Y., Heath S., Sõber S., Parsa A., Luan J., Arora P., Zhang F., Lucas G., Hicks A.A., Jackson A.U., Peden J.F., Tanaka T., Wild S.H., Rudan I., Igl W., Milaneschi Y., Parker A.N., Fava C., Chambers J.C., Fox E.R., Kumari M., Go M.J., van der Harst P., Kao W.H.L., Sjögren M., Vinay D.G., Alexander M., Tabara Y., Shaw-Hawkins S., Whincup P.H., Liu Y., Shi G., Kuusisto J., Tayo B., Seielstad M., SIM XUELING, Hoang Nguyen K.-D., Lehtimäki T., Matullo G., Wu Y., Gaunt T.R., Onland-Moret N.C., Cooper M.N., Platou C.G.P., Org E., Hardy R., Dahgam S., Palmen J., Vitart V., Braund P.S., Kuznetsova T., Uiterwaal C.S.P.M., Adeyemo A., Palmas W., Campbell H., Ludwig B., Tomaszewski M., Tzoulaki I., Palmer N.D., CARDIoGRAM consortium, CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, CHARGE-HF consortium, Aspelund T., Garcia M., Chang Y.-P.C., O’Connell J.R., Steinle N.I., Grobbee D.E., Arking D.E., Kardia S.L., Morrison A.C., Hernandez D., Najjar S., McArdle W.L., Hadley D., Brown M.J., Connell J.M., Hingorani A.D., Day I.N.M., Lawlor D.A., Beilby J.P., Lawrence R.W., Clarke R., Collins R., Hopewell J.C., Ongen H., Dreisbach A.W., Li Y., Young J.H., Bis J.C., Kähönen M., Viikari J., Adair L.S., Lee N.R., Chen M.-H., Olden M., Pattaro C., Hoffman Bolton J.A., Köttgen A., Bergmann S., Mooser V., Chaturvedi N., Frayling T.M., Islam M., Jafar T.H., Erdmann J., Kulkarni S.R., Bornstein S.R., Grässler J., Groop L., Voight B.F., Kettunen J., Howard P., Taylor A., Guarrera S., Ricceri F., Emilsson V., Plump A., Barroso I., Khaw K.-T., Weder A.B., Hunt S.C., Sun Y.V., Bergman R.N., Collins F.S., Bonnycastle L.L., Scott L.J., Stringham H.M., Peltonen L., Perola M., Vartiainen E., Brand S.-M., Staessen J.A., Wang T.J., Burton P.R., Soler Artigas M., Dong Y., Snieder H., Wang X., Zhu H., Lohman K.K., Rudock M.E., Heckbert S.R., Smith N.L., Wiggins K.L., Doumatey A., Shriner D., Veldre G., Viigimaa M., Kinra S., Prabhakaran D., Tripathy V., Langefeld C.D., Rosengren A., Thelle D.S., Maria A.C., Singleton A., Forrester T., Hilton G., McKenzie C.A., Salako T., Iwai N., Kita Y., Ogihara T., Ohkubo T., Okamura T., Ueshima H., Umemura S., Eyheramendy S., Meitinger T., Wichmann H.-E., Shin Cho Y., Kim H.-L., Lee J.-Y., Scott J., Sehmi J.S., Zhang W., Hedblad B., Nilsson P., Davey Smith G., Wong A., Narisu N., Stan?áková A., Raffel L.J., Yao J., Kathiresan S., O’Donnell C., Schwartz S.M., Arfan Ikram M., Longstreth W.T., Jr., Mosley T.H., Seshadri S., Shrine N.R.G., Wain L.V., Morken M.A., Swift A.J., Laitinen J., Prokopenko I., Zitting P., Cooper J.A., Humphries S.E., Danesh J., Rasheed A., Goel A., Hamsten A., Watkins H., Bakker S.J.L., van Gilst W.H., Janipalli C.S., RadhaMani K., Yajnik C.S., Hofman A., Mattace-Raso F.U.S., Oostra B.A., Demirkan A., Isaacs A., Rivadeneira F., Lakatta E.G., Orru M., Scuteri A., Ala-Korpela M., Kangas A.J., Lyytikäinen L.-P., Soininen P., Tukiainen T., Würtz P., Ong R.T.-H., Dörr M., Kroemer H.K., Völker U., Völzke H., Galan P., Hercberg S., Lathrop M., Zelenika D., Deloukas P., Mangino M., Spector T.D., Zhai G., Meschia J.F., Nalls M.A., Sharma P., Terzic J., Kranthi Kumar M.J., Denniff M., Zukowska-Szczechowska E., Wagenknecht L.E., Fowkes F.G.R., Charchar F.J., Schwarz P.E.H., Hayward C., Guo X., Rotimi C., Bots M.L., Brand E., Samani N.J., Polasek O., Talmud P.J., Nyberg F., Kuh D., Laan M., Hveem K., Palmer L.J., van der Schouw Y.T., Casas J.P., Mohlke K.L., Vineis P., Raitakari O., Ganesh S.K., Wong T.Y., Tai E.S., Cooper R.S., Laakso M., Rao D.C., Harris T.B., Morris R.W., Dominiczak A.F., Kivimaki M., Marmot M.G., Miki T., Saleheen D., Chandak G.R., Coresh J., Navis G., Salomaa V., Han B.-G., Zhu X., Kooner J.S., Melander O., Ridker P.M., Bandinelli S., Gyllensten U.B., Wright A.F., Wilson J.F., Ferrucci L., Farrall M., Tuomilehto J., Pramstaller P.P., Elosua R., Soranzo N., Sijbrands E.J.G., Altshuler D., Loos R.J.F., Shuldiner A.R., Gieger C., Meneton P., Uitterlinden A.G., Wareham N.J., Gudnason V., Rotter J.I., Rettig R., Uda M., Strachan D.P., Witteman J.C.M., Hartikainen A.-L., Witteman J.C.M., Boerwinkle E., Vasan R.S., Larson M.G., Larson M.G., Järvelin M.-R., Psaty B.M., Abecasis G.R., Chakravarti A., Elliott P., van Duijn C.M., Newton-Cheh C., Levy D., Caulfield M.J., Johnson T.
Published 2018