Estabilishing the Genetic Etiology in common human phenotypes

by SIM XUELING
Published 2012

Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases

by Chai, Jin-Fang, Raichur, Suryaprakash, Khor, Ing Wei, Torta, Federico, Chew, Wee Siong, Herr, Deron Raymond, Ching, Jianhong, Kovalik, Jean-Paul, Khoo, Chin Meng, Wenk, Markus R, Tai, E Shyong, Sim, Xueling
Published 2020

Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood : an EWAS in multi-ethnic Asian individuals

by Chen, Yuqing, Kassam, Irfahan, Lau, Suk Hiang, Kooner, Jaspal S., Wilson, Rory, Peters, Annette, Winkelmann, Juliane, Chambers, John C., Chow, Vincent T., Khor, Chiea Chuen, Van Dam, Rob M., Teo, Yik-Ying, Loh, Marie, Sim, Xueling
Published 2021

Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians

by Hwang J.-Y., Sim Xueling, Wu Y., Liang J., Tabara Y., Hu C., Hara K., Tam C.H.T., Cai Q., Zhao Q., Ong, Rick Twee Hee, Nabika, Toru, Teo, Yik Ying, Tai, E. Shyong
Published 2016

Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals

by Chen, Yuqing, Kassam, Irfahan, Lau, Suk Hiang, Kooner, Jaspal S., Wilson, Rory, Peters, Annette, Winkelmann, Juliane, Chambers, John C., Chow, Vincent T., Khor, Chiea Chuen, Van Dam, Rob M., Teo, Yik-Ying, Loh, Marie, Sim, Xueling
Published 2022

Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence

by Chew, Wee Siong, Torta, Federico, Ji, Shanshan, Choi, Hyungwon, Begum, Husna, Sim, Xueling, Khoo, Chin Meng, Khoo, Eric Yin Hao, Ong, Wei-Yi, Van Dam, Rob M, Wenk, Markus R, Tai, E Shyong, Herr, Deron R
Published 2020

Ethnicity-specific skeletal muscle transcriptional signatures and their relevance to insulin resistance in Singapore

by Tan, Amelia Li Min, Langley, Sarah R., Tan, Chee Fan, Chai, Jin Fang, Khoo, Chin Meng, Leow, Melvin Khee-Shing, Khoo, Eric Yin Hao, Moreno-Moral, Aida, Pravenec, Michal, Rotival, Maxime, Sadananthan, Suresh Anand, Velan, S. Sendhil, Venkataraman, Kavita, Chong, Yap Seng, Lee, Yung Seng, Sim, Xueling, Stunkel, Walter, Liu, Mei Hui, Tai, E. Shyong, Petretto, Enrico
Published 2021

A catalogue of structural variation across ancestrally diverse Asian genomes

by Tan, Joanna Hui Juan, Li, Zhihui, Porta, Mar Gonzalez, Rajaby, Ramesh, Lim, Weng Khong, Tan, Ye An, Jimenez, Rodrigo Toro, Teo, Renyi, Hebrard, Maxime, Ow, Jack Ling, Ang, Shimin, Jeyakani, Justin, Chong, Yap Seng, Lim, Tock Han, Goh, Liuh Ling, Tham, Yih Chung, Leong, Khai Pang, Chin, Calvin Woon Loong, Davila, Sonia, Karnani, Neerja, Cheng, Ching-Yu, Chambers, John, Tai, E Shyong, Liu, Jianjun, Sim, Xueling, Sung, Wing Kin, Prabhakar, Shyam, Tan, Patrick, Bertin, Nicolas
Published 2025

APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

by Goyal, Shiwali, Tanigawa, Yosuke, Zhang, Weihua, Chai, Jin-Fang, Almeida, Marcio, Sim, Xueling, Lerner, Megan, Chainakul, Juliane, Ramiu, Jonathan Garcia, Seraphin, Chanel, Apple, Blair, Vaughan, April, Muniu, James, Peralta, Juan, Lehman, Donna M., Ralhan, Sarju, Wander, Gurpreet S., Singh, Jai Rup, Mehra, Narinder K., Sidorov, Evgeny, Peyton, Marvin D., Blackett, Piers R., Curran, Joanne E., Tai, E Shyong, van Dam, Rob, Cheng, Ching-Yu, Duggirala, Ravindranath, Blangero, John, Chambers, John Campbell, Sabanayagam, Charumathi, Kooner, Jaspal S., Rivas, Manuel A., Aston, Christopher E., Sanghera, Dharambir K.
Published 2022

Analysis of clinically relevant variants from ancestrally diverse Asian genomes

by Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John Campbell, Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S., Ngeow, Joanne, Lim, Weng Khong
Published 2023

APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

by Goyal, Shiwali, Tanigawa, Yosuke, Zhang, Weihua, Chai, Jin-Fang, Almeida, Marcio, Sim, Xueling, Lerner, Megan, Chainakul, Juliane, Ramiu, Jonathan Garcia, Seraphin, Chanel, Apple, Blair, Vaughan, April, Muniu, James, Peralta, Juan, Lehman, Donna M., Ralhan, Sarju, Wander, Gurpreet S., Singh, Jai Rup, Mehra, Narinder K., Sidorov, Evgeny, Peyton, Marvin D., Blackett, Piers R., Curran, Joanne E., Tai, E. Shyong, Van Dam, Rob, Cheng, Ching-Yu, Duggirala, Ravindranath, Blangero, John, Chambers, John C., Sabanayagam, Charumathi, Kooner, Jaspal S., Rivas, Manuel A., Aston, Christopher E., Sanghera, Dharambir K.
Published 2022

Analysis of clinically relevant variants from ancestrally diverse Asian genomes.

by Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, SG10K_Health Consortium, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John C, Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S, Ngeow, Joanne, Lim, Weng Khong
Published 2022

Cohort profile: The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers

by Ho, Peh Joo, Yeoh, Yen Shing, Miao, Hui, Lim, Swee Ho, Tan, Ern Yu, Tan, Benita Kiat Tee, Tan, Veronique Kiak Mien, Tan, Su Ming, Yong, Wei Sean, Wong, Fuh Yong, Madhukumar, Preetha, Chan, Ching Wan, Iau, Philip Tsau Choong, Lee, Soo Chin, Putti, Thomas, Buhari, Shaik Ahmad, Lee, Jin Yee, Lim, Geok Hoon, Woo, Evan, Yan, Zhiyan, Chan, Patrick Mun Yew, Chen, Juliana Jia Chuan, Lu, Sarah Qinghui, Dent, Rebecca, Lee, Wai Peng, Mok, Chi Wei, Seah, Jaime Chin Mui, Sim, Xueling, van Dam, Rob Martinus, Chia, Kee Seng, Li, Jingmei, Hartman, Mikael
Published 2021

A five-safes approach to a secure and scalable genomics data repository

by Shih, Chih Chuan, Chen, Jieqi, Lee, Ai Shan, Bertin, Nicolas, Hebrard, Maxime, Khor, Chiea Chuen, Li, Zheng, Tan, Joanna Juan Hui, Meah, Wee Yang, Peh, Su Qin, Mok, Shi Qi, Sim, Kar Seng, Liu, Jianjun, Wang, Ling, Wong, Eleanor, Li, Jingmei, Aung, Tin, Cheng, Ching-Yu, Heng, Chew-Kiat, Yuan, Jian-Min, Koh, Woon-Puay, Saw, Seang Mei, Friedlander, Yechiel, Sim, Xueling, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Tien Yin, Karnani, Neerja, Leong, Khai Pang, Yeo, Khung Keong, Chambers, John C., Lim, Su Chi, Goh, Rick Siow Mong, Tan, Patrick, Dorajoo, Rajkumar
Published 2023

Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification

by Ho, Peh Joo, Ho, Weang Kee, Khng, Alexis J, Yeoh, Yen Shing, Tan, Benita Kiat-Tee, Tan, Ern Yu, Lim, Geok Hoon, Tan, Su-Ming, Tan, Veronique Kiak Mien, Yip, Cheng-Har, Mohd-Taib, Nur-Aishah, Wong, Fuh Yong, Lim, Elaine Hsuen, Ngeow, Joanne, Chay, Wen Yee, Leong, Lester Chee Hao, Yong, Wei Sean, Seah, Chin Mui, Tang, Siau Wei, Ng, Celene Wei Qi, Yan, Zhiyan, Lee, Jung Ah, Rahmat, Kartini, Islam, Tania, Hassan, Tiara, Tai, Mei-Chee, Khor, Chiea Chuen, Yuan, Jian-Min, Koh, Woon-Puay, Sim, Xueling, Dunning, Alison M, Bolla, Manjeet K, Antoniou, Antonis C, Teo, Soo-Hwang, Li, Jingmei, Hartman, Mikael
Published 2023

Identification of genetic effects underlying type 2 diabetes in South Asian and European populations

by Loh, Marie, Zhang, Weihua, Ng, Hong Kiat, Schmid, Katharina, Lamri, Amel, Tong, Lin, Meraj Ahmad, Lee, Jung-Jin, Ng, Maggie C. Y., Petty, Lauren E., Spracklen, Cassandra N., Takeuchi, Fumihiko, Md. Tariqul Islam, Jasmine, Farzana, Kasturiratne, Anuradhani, Muhammad Kibriya, Mohlke, Karen L., Paré, Guillaume, Prasad, Gauri, Mohammad Shahriar, Chee, Miao Ling, de Silva, H. Janaka, Engert, James C., Gerstein, Hertzel C., Mani, K. Radha, Sabanayagam, Charumathi, Vujkovic, Marijana, Wickremasinghe, Ananda R., Wong, Tien Yin, Yajnik, Chittaranjan S., Salim Yusuf, Habibul Ahsan, Bharadwaj, Dwaipayan, Anand, Sonia S., Below, Jennifer E., Boehnke, Michael, Bowden, Donald W., Chandak, Giriraj R., Cheng, Ching-Yu, Kato, Norihiro, Mahajan, Anubha, Sim, Xueling, McCarthy, Mark I., Morris, Andrew P., Kooner, Jaspal S., Saleheen, Danish, Chambers, John C.
Published 2022

The Singapore national precision medicine strategy

by Wong, Eleanor, Bertin, Nicolas, Hebrard, Maxime, Tirado-Magallanes, Roberto, Bellis, Claire, Lim, Weng Khong, Chua, Chee Yong, Tong, Philomena Mei Lin, Chua, Raymond, Mak, Kenneth, Lim, Tit Meng, Cheong, Wei Yang, Thien, Kwee Eng, Goh, Khean Teik, Chai, Jin-Fang, Lee, Jimmy, Sung, Joseph Jao Yiu, Wong, Tien Yin, Chin, Calvin Woon Loong, Gluckman, Peter D., Goh, Liuh Ling, Ban, Kenneth Hon Kim, Tan, Tin Wee, Sim, Xueling, Cheng, Ching-Yu, Davila, Sonia, Karnani, Neerja, Leong, Khai Pang, Liu, Jianjun, Prabhakar, Shyam, Maurer-Stroh, Sebastian, Verma, Chandra Shekhar, Krishnaswamy, Pavitra, Goh, Rick Siow Mong, Chia, Irenaeus, Ho, Clarissa, Low, Doreen, Virabhak, Suchin, Yong, Jacklyn, Zheng, Weiling, Seow, Shih Wee, Seck, Yee Kwang, Koh, Mingshi, Chambers, John Campbell, Tai, E. Shyong, Tan, Patrick
Published 2023

Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk (vol 55, pg 1435, 2023)

by Wilcox, Naomi, Dumont, Martine, Gonzalez-Neira, Anna, Carvalho, Sara, Beauparlant, Charles Joly, Crotti, Marco, Luccarini, Craig, Soucy, Penny, Dubois, Stephane, Nunez-Torres, Rocio, Pita, Guillermo, Gardner, Eugene J, Dennis, Joe, Alonso, M Rosario, Alvarez, Nuria, Baynes, Caroline, Collin-Deschesnes, Annie Claude, Desjardins, Sylvie, Becher, Heiko, Behrens, Sabine, Bolla, Manjeet K, Castelao, Jose E, Chang-Claude, Jenny, Cornelissen, Sten, Dork, Thilo, Engel, Christoph, Gago-Dominguez, Manuela, Guenel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hartman, Mikael, Herraez, Belen, Jung, Audrey, Keeman, Renske, Kiechle, Marion, Li, Jingmei, Loizidou, Maria A, Lush, Michael, Michailidou, Kyriaki, Panayiotidis, Mihalis I, Sim, Xueling, Teo, Soo Hwang, Tyrer, Jonathan P, van der Kolk, Lizet E, Wahlstrom, Cecilia, Wang, Qin, Perry, John RB, Benitez, Javier, Schmidt, Marjanka K, Schmutzler, Rita K, Pharoah, Paul DP, Droit, Arnaud, Dunning, Alison M, Kvist, Anders, Devilee, Peter, Easton, Douglas F, Simard, Jacques
Published 2023

Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk

by Wilcox, Naomi, Dumont, Martine, González-Neira, Anna, Carvalho, Sara, Beauparlant, Charles Joly, Crotti, Marco, Luccarini, Craig, Soucy, Penny, Dubois, Stéphane, Nuñez-Torres, Rocio, Pita, Guillermo, Gardner, Eugene J., Dennis, Joe, Alonso, M. Rosario, Álvarez, Nuria, Baynes, Caroline, Collin-Deschesnes, Annie Claude, Desjardins, Sylvie, Becher, Heiko, Behrens, Sabine, Bolla, Manjeet K., Castelao, Jose E., Chang-Claude, Jenny, Cornelissen, Sten, Dörk, Thilo, Engel, Christoph, Gago-Dominguez, Manuela, Guénel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hartman, Mikael, Herráez, Belén, Jung, Audrey, Keeman, Renske, Kiechle, Marion, Li, Jingmei, Loizidou, Maria A., Lush, Michael, Michailidou, Kyriaki, Panayiotidis, Mihalis I., Sim, Xueling, Teo, Soo Hwang, Tyrer, Jonathan P., van der Kolk, Lizet E., Wahlström, Cecilia, Wang, Qin, Perry, John R. B., Benitez, Javier, Schmidt, Marjanka K., Schmutzler, Rita K., Pharoah, Paul D. P., Droit, Arnaud, Dunning, Alison M., Kvist, Anders, Devilee, Peter, Easton, Douglas F., Simard, Jacques, Tan, Benita Kiat-Tee, Tan,Veronique Kiak Mien, Tan, Su-Ming, Lim, Geok Hoon, Tan, Ern Yu, Ho, Peh Joo, Khng, Alexis Jiaying
Published 2024

A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

by van Zuydam, Natalie R., Ahlqvist, Emma, Sandholm, Niina, Deshmukh, Harshal, Rayner, N. William, Abdalla, Moustafa, Ladenvall, Claes, Ziemek, Daniel, Fauman, Eric, Robertson, Neil R., McKeigue, Paul M., Valo, Erkka, Forsblom, Carol, Harjutsalo, Valma, Perna, Annalisa, Rurali, Erica, Marcovecchio, M Loredana, Igo, Robert P., Salem, Rany M., Perico, Norberto, Lajer, Maria, Käräjämäki, Annemari, Imamura, Minako, Kubo, Michiaki, Takahashi, Atsushi, Sim, Xueling, Liu, Jianjun, van Dam, Rob M., Jiang, Guozhi, Tam, Claudia H. T., Luk, Andrea O. Y., Lee, Heung Man, Lim, Cadmon K. P., Szeto, Cheuk Chun, So, Wing Yee, Chan, Juliana C. N., Ang, Su Fen, Dorajoo, Rajkumar, Wang, Ling, Clara, Tan Si Hua, McKnight, Amy-Jayne, Duffy, Seamus, Pezzolesi, Marcus G., Marre, Michel, Gyorgy, Beata, Hadjadj, Samy, Hiraki, Linda T., Ahluwalia, Tarunveer S., Almgren, Peter, Schulz, Christina-Alexandra, Orho-Melander, Marju, Linneberg, Allan, Christensen, Cramer, Witte, Daniel R., Grarup, Niels, Brandslund, Ivan, Melander, Olle, Paterson, Andrew D., Tregouet, David, Maxwell, Alexander P., Lim, Su Chi, Ma, Ronald C. W., Tai, E. Shyong, Maeda, Shiro, Lyssenko, Valeriya, Tuomi, Tiinamaija, Krolewski, Andrzej S., Rich, Stephen S., Hirschhorn, Joel N., Florez, Jose C., Dunger, David, Pedersen, Oluf, Hansen, Torben, Rossing, Peter, Remuzzi, Giuseppe, Brosnan, Mary Julia, Palmer, Colin N. A., Groop, Per-Henrik, Colhoun, Helen M., Groop, Leif C., McCarthy, Mark I.
Published 2020