Targeting of the MNK-eIF4E axis in blast crisis Chronic myeloid leukemia inhibits leukemia stem cell function

by Lim, S., Saw, T.Y., Zhang, M., Janes, M.R., Nacro, K., Hill, J., Lim, A.Q., Chang, C.-T., Fruman, D.A., Rizzieri, D.A., Tan, S.Y., Fan, H., Chuah, C.T.H., Ong, S.T.
Published 2014

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

by Janes, M.R., Limon, J.J., So, L., Chen, J., Lim, R.J., Chavez, M.A., Vu, C., Lilly, M.B., Mallya, S., Ong, S.T., Konopleva, M., Martin, M.B., Ren, P., Liu, Y., Rommel, C., Fruman, D.A.
Published 2016

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

by Glaviano, A, Foo, ASC, Lam, HY, Yap, KCH, Jacot, W, Jones, RH, Eng, H, Nair, MG, Makvandi, P, Geoerger, B, Kulke, MH, Baird, RD, Prabhu, JS, Carbone, D, Pecoraro, C, Teh, DBL, Sethi, G, Cavalieri, V, Lin, KH, Javidi-Sharifi, NR, Toska, E, Davids, MS, Brown, JR, Diana, P, Stebbing, J, Fruman, DA, Kumar, AP
Published 2023