Bacterial-induced cell fusion is a danger signal triggering cGAS-STING pathway via micronuclei formation

by Ku, Joanne Wei Kay, Chen, Yahua, Lim, Bryan Jian Wei, Gasser, Stephan, Crasta, Karen Carmelina, Gan, Yunn-Hwen
Published 2022

cGAS–STING cytosolic DNA sensing pathway is suppressed by JAK2-STAT3 in tumor cells

by Suter, Manuel Adrian, Tan, Nikki Y., Thiam, Chung Hwee, Khatoo, Muznah, MacAry, Paul A., Angeli, Veronique, Gasser, Stephan, Zhang, Y. L.
Published 2022

Tumoral STING is required for effective anticancer immunity

by Suter, Manuel Adrian, Zhang, Wendy Ya Ling, Khatoo, Muznah Bte Nazar Khan, Tan, Nikki Ya Ling, Too, Chien Tei, Tripathi, Shubhita, MacAry, Paul A, Angeli, Veronique, Gasser, Stephan
Published 2023

Macrophage IL-1 & beta; contributes to tumorigenesis through paracrine AIM2 inflammasome activation in the tumor microenvironment

by Chew, Zhi Huan, Cui, Jianzhou, Sachaphibulkij, Karishma, Tan, Isabelle, Kar, Shreya, Koh, Kai Kiat, Singh, Kritika, Lim, Hong Meng, Lee, Soo Chin, Kumar, Alan Prem, Gasser, Stephan, Lim, Lina HK
Published 2023

Regulation of adipogenic differentiation and adipose tissue inflammation by interferon regulatory factor 3

by Tang, Peng, Virtue, Sam, Goie, Jian Yi Gerald, Png, Chin Wen, Guo, Jing, Li, Ying, Jiao, Huipeng, Chua, Yen Leong, Campbell, Mark, Moreno-Navarrete, Jose Maria, Shabbir, Asim, Fernández-Real, J.-M., Gasser, Stephan, Kemeny, David Michael, Yang, Henry, Vidal-Puig, Antonio, Zhang, Yongliang
Published 2022