Personalised randomised controlled trial designs—a new paradigm to define optimal treatments for carbapenem-resistant infections

by A. Sarah Walker, Ian R. White, Rebecca M. Turner, Li Yang Hsu, Tsin Wen Yeo, Nicholas J. White, Mike Sharland, Guy E. Thwaites
Published 2022

High-performance liquid chromatography with time-programmed fluorescence detection for the quantification of Levofloxacin in human plasma and cerebrospinal fluid in adults with tub...

by Pham Van Toi, Thomas Pouplin, Nguyen Duc Khanh Tho, Pham Nguyen Phuong, Tran Thi Hong Chau, Nguyen Thuy Thuong Thuong, Dorothee Heemskerk, Tran Tinh Hien, Guy E. Thwaites
Published 2018

An HPLC method with diode array detector for the simultaneous quantification of chloroquine and desethylchloroquine in plasma and whole blood samples from Plasmodium vivax patients...

by Toi Van Pham, Phuong Pham Nguyen, Tho Nguyen Duc Khanh, Nhien Nguyen Thanh Thuy, Ca Nguyen Thuy Nha, Thomas Pouplin, Jeremy Farrar, Guy E. Thwaites, Hien Tran Tinh
Published 2018

Achieving affordable critical care in low-income and middle-income countries

by Hugo C. Turner, Nguyen Van Hao, Sophie Yacoub, Van Minh Tu Hoang, David A. Clifton, Guy E. Thwaites, Arjen M. Dondorp, C. Louise Thwaites, Nguyen Van Vinh Chau
Published 2020

The clinical benefit of adjunctive dexamethasone in tuberculous meningitis is not associated with measurable attenuation of peripheral or local immune responses

by Cameron P. Simmons, Guy E. Thwaites, Nguyen Than Ha Quyen, Tran Thi Hong Chau, Pham Phuong Mai, Nguyen Thi Dung, Kasia Stepniewska, Nicholas J. White, Tran Tinh Hien, Jeremy Farrar
Published 2018

Do intracerebral cytokine responses explain the harmful effects of dexamethasone in human immunodeficiency virus–associated cryptococcal meningitis?

by Justin Beardsley, Nhat L.T. Hoang, Freddie M. Kibengo, Nguyen L.N. Tung, Tran Q. Binh, Le Q. Hung, Wirongrong Chierakul, Guy E. Thwaites, Nguyen V.V. Chau, Thuong T.T. Nguyen, Ronald B. Geskus, Jeremy N. Day
Published 2020

Clinical presentations, diagnosis, mortality and prognostic markers of tuberculous meningitis in Vietnamese children: A prospective descriptive study

by Nguyen Duc Bang, Maxine Caws, Thai Thanh Truc, Tran Ngoc Duong, Nguyen Huy Dung, Dang Thi Minh Ha, Guy E. Thwaites, Doortje Heemskerk, Joel Tarning, Laura Merson, Pham Van Toi, Jeremy J. Farrar, Marcel Wolbers, Thomas Pouplin, Jeremy N. Day
Published 2018

The persistence and oscillations of submicroscopic Plasmodium falciparum and Plasmodium vivax infections over time in Vietnam: an open cohort study

by Thuy Nhien Nguyen, Lorenz von Seidlein, Tuong Vy Nguyen, Phuc Nhi Truong, Son Do Hung, Huong Thu Pham, Tam Uyen Nguyen, Thanh Dong Le, Van Hue Dao, Mavuto Mukaka, Nicholas PJ Day, Nicholas J. White, Arjen M. Dondorp, Guy E. Thwaites, Tran Tinh Hien
Published 2019

The prevalence, incidence and prevention of Plasmodium falciparum infections in forest rangers in Bu Gia Map National Park, Binh Phuoc province, Vietnam: A pilot study NCT02788864...

by Do Hung Son, Nguyen Thuy-Nhien, Lorenz Von Seidlein, Truong Le Phuc-Nhi, Ngo Thi Phu, Nguyen Thi Kim Tuyen, Nguyen Huyen Tran, Nguyen Van Dung, Bui Van Quan, Nicholas P.J. Day, Arjen M. Dondorp, Nicholas J. White, Guy E. Thwaites, Tran Tinh Hien
Published 2018

Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa

by Elin Näsström, Christopher M. Parry, Nga Tran Vu Thieu, Rapeephan R. Maude, Hanna K. de Jong, Masako Fukushima, Olena Rzhepishevska, Florian Marks, Ursula Panzner, Justin Im, Hyonjin Jeon, Seeun Park, Zabeen Chaudhury, Aniruddha Ghose, Rasheda Samad, Tan Trinh Van, Anders Johansson, Arjen M. Dondorp, Guy E. Thwaites, Abul Faiz, Henrik Antti, Stephen Baker
Published 2018

An open label randomized controlled trial of tamoxifen combined with amphotericin B and Fluconazole for cryptococcal meningitis

by Nguyen Thi Thuy Ngan, Nhat Thanh Hoang Le, Nguyen Ngo Vi Vi, Ninh Thi Thanh Van, Nguyen Thi Hoang Mai, Duong Van Anh, Phan Hai Trieu, Nguyen Phu Huong Lan, Nguyen Hoan Phu, Nguyen van Vinh Chau, David G. Lalloo, William Hope, Justin Beardsley, Nicholas J. White, Ronald Geskus, Guy E. Thwaites, Damian Krysan, Luong Thi Hue Tai, Evelyne Kestelyn, Tran Quang Binh, Le Quoc Hung, Nguyen Le Nhu Tung, Jeremy N. Day
Published 2022

Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Fi...

by Koukeo Phommasone, Frank van Leth, Thomas J. Peto, Jordi Landier, Thuy Nhien Nguyen, Rupam Tripura, Tiengkham Pongvongsa, Khin Maung Lwin, Ladda Kajeechiwa, May Myo Thwin, Daniel M. Parker, Jacher Wiladphaingern, Suphak Nosten, Stephane Proux, Chea Nguon, Chan Davoeung, Huy Rekol, Bipin Adhikari, Cholrawee Promnarate, Kesinee Chotivanich, Borimas Hanboonkunupakarn, Podjanee Jittmala, Phaik Yeong Cheah, Mehul Dhorda, Mallika Imwong, Mavuto Mukaka, Pimnara Peerawaranun, Sasithon Pukrittayakamee, Paul N. Newton, Guy E. Thwaites, Nicholas P.J. Day, Mayfong Mayxay, Tran Tinh Hien, Francois H. Nosten, Frank Cobelens, Arjen M. Dondorp, Nicholas J. White, Lorenz von Seidlein
Published 2020

Human versus equine intramuscular antitoxin, with or without human intrathecal antitoxin, for the treatment of adults with tetanus: a 2 × 2 factorial randomised controlled trial...

by Nguyen Van Hao, Huynh Thi Loan, Lam Minh Yen, Evelyne Kestelyn, Duc Du Hong, Duong Bich Thuy, Nguyen Thanh Nguyen, Ha Thi Hai Duong, Tran Thi Diem Thuy, Phung Tran Huy Nhat, Phan Nguyen Quoc Khanh, Nguyen Thi Phuong Dung, Nguyen Hoan Phu, Nguyen Thanh Phong, Pham Thi Lieu, Pham Thi Tuyen, Bui Thi Bich Hanh, Ho Dang Trung Nghia, Pham Kieu Nguyet Oanh, Phan Vinh Tho, Tran Tan Thanh, Hugo C. Turner, H. Rogier van Doorn, Le Van Tan, Duncan Wyncoll, Nicholas PJ Day, Ronald B. Geskus, Guy E. Thwaites, Nguyen Van Vinh Chau, C. Louise Thwaites
Published 2022

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in southeast Asia: A cluster randomised trial

by Lorenz von Seidlein, Thomas J. Peto, Jordi Landier, Thuy Nhien Nguyen, Rupam Tripura, Koukeo Phommasone, Tiengkham Pongvongsa, Khin Maung Lwin, Lilly Keereecharoen, Ladda Kajeechiwa, May Myo Thwin, Daniel M. Parker, Jacher Wiladphaingern, Suphak Nosten, Stephane Proux, Vincent Corbel, Nguyen Tuong-Vy, Truong Le Phuc-Nhi, Do Hung Son, Pham Nguyen Huong-Thu, Nguyen Thi Kim Tuyen, Nguyen Thanh Tien, Le Thanh Dong, Dao Van Hue, Huynh Hong Quang, Chea Nguon, Chan Davoeung, Huy Rekol, Bipin Adhikari, Gisela Henriques, Panom Phongmany, Preyanan Suangkanarat, Atthanee Jeeyapant, Benchawan Vihokhern, Rob W. van der Pluijm, Yoel Lubell, Lisa J. White, Ricardo Aguas, Cholrawee Promnarate, Pasathorn Sirithiranont, Benoit Malleret, Laurent Rénia, Carl Onsjö, Xin Hui Chan, Jeremy Chalk, Olivo Miotto, Krittaya Patumrat, Kesinee Chotivanich, Borimas Hanboonkunupakarn, Podjanee Jittmala, Nils Kaehler, Phaik Yeong Cheah, Christopher Pell, Mehul Dhorda, Mallika Imwong, Georges Snounou, Mavuto Mukaka, Pimnara Peerawaranun, Sue J. Lee, Julie A. Simpson, Sasithon Pukrittayakamee, Pratap Singhasivanon, Martin P. Grobusch, Frank Cobelens, Frank Smithuis, Paul N. Newton, Guy E. Thwaites, Nicholas P.J. Day, Mayfong Mayxay, Tran Tinh Hien, Francois H. Nosten, Arjen M. Dondorp, Nicholas J. White
Published 2020