Artemisinin and multidrug-resistant Plasmodium falciparum - a threat for malaria control and elimination

by Mehul Dhorda, Chanaki Amaratunga, Arjen M. Dondorp
Published 2022

Triple Artemisinin-Based Combination Therapies for Malaria – A New Paradigm?

by Rob W. van der Pluijm, Chanaki Amaratunga, Mehul Dhorda, Arjen M. Dondorp
Published 2020

Pharmacokinetic properties of artemether, dihydroartemisinin, lumefantrine, and quinine in pregnant women with uncomplicated plasmodium falciparum malaria in uganda

by Joel Tarning, Frank Kloprogge, Mehul Dhorda, Vincent Jullien, Francois Nosten, Nicholas J. White, Philippe J. Guerin, Patrice Piola
Published 2018

Deploying triple artemisinin-based combination therapy (TACT) for malaria treatment in Africa: ethical and practical considerations

by Paulina Tindana, Freek de Haan, Chanaki Amaratunga, Mehul Dhorda, Rob W. van der Pluijm, Arjen M. Dondorp, Phaik Yeong Cheah
Published 2022

A comprehensive RNA handling and transcriptomics guide for high-throughput processing of Plasmodium blood-stage samples

by Michal Kucharski, Jaishree Tripathi, Sourav Nayak, Lei Zhu, Grennady Wirjanata, Rob W. Van Der Pluijm, Mehul Dhorda, Arjen Dondorp, Zbynek Bozdech
Published 2020

Population pharmacokinetics of quinine in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda

by Frank Kloprogge, Vincent Jullien, Patrice Piola, Mehul Dhorda, Sulaiman Muwanga, François Nosten, Nicholas P. Nicholas, Nicholas J. White, Philippe J. Guerin, Joel Tarning
Published 2018

Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial

by Atis Muehlenbachs, Carolyn Nabasumba, Rose McGready, Eleanor Turyakira, Benon Tumwebaze, Mehul Dhorda, Dan Nyehangane, Aisha Nalusaji, François Nosten, Philippe J. Guerin, Patrice Piola
Published 2018

Efficacy and safety of artemether-lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority...

by Patrice Piola, Carolyn Nabasumba, Eleanor Turyakira, Mehul Dhorda, Niklas Lindegardh, Dan Nyehangane, Georges Snounou, Elizabeth A. Ashley, Rose McGready, Francois Nosten, Philippe J. Guerin
Published 2018

Mapping genetic markers of artemisinin resistance in Plasmodium falciparum malaria in Asia: a systematic review and spatiotemporal analysis

by Frank M. Kagoro, Karen I. Barnes, Kevin Marsh, Nattwut Ekapirat, Chris Erwin G. Mercado, Ipsita Sinha, Georgina Humphreys, Mehul Dhorda, Philippe J. Guerin, Richard J. Maude
Published 2022

An inventory of supranational antimicrobial resistance surveillance networks involving low- and middle-income countries since 2000

by Elizabeth A. Ashley, Judith Recht, Arlene Chua, David Dance, Mehul Dhorda, Nigel V. Thomas, Nisha Ranganathan, Paul Turner, Philippe J. Guerin, Nicholas J. White, Nicholas P. Day
Published 2019

Molecular surveillance for operationally relevant genetic polymorphisms in Plasmodium falciparum in Southern Chad, 2016–2017

by Sukanta Das, Clément Kérah-Hinzoumbé, Moundiné Kebféné, Suttipat Srisutham, Tog Yeum Nagorngar, Naowarat Saralamba, Ranitha Vongpromek, Teeradet Khomvarn, Carol H. Sibley, Philippe J. Guérin, Mallika Imwong, Mehul Dhorda
Published 2022

Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda

by Joel Tarning, Frank Kloprogge, Patrice Piola, Mehul Dhorda, Sulaiman Muwanga, Eleanor Turyakira, Nitra Nuengchamnong, François Nosten, Nicholas P J Day, Nicholas J. White, Philippe J. Guerin, Niklas Lindegardh
Published 2018

Artemisinin Resistance and Stage Dependency of Parasite Clearance in Falciparum Malaria

by Benjamas Intharabut, Hugh W. Kingston, Ketsanee Srinamon, Elizabeth A. Ashley, Mallika Imwong, Mehul Dhorda, Charles Woodrow, Kasia Stepniewska, Kamolrat Silamut, Nicholas P.J. Day, Arjen M. Dondorp, Nicholas J. White
Published 2020

Making data map-worthy—enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African...

by Frank M. Kagoro, Elizabeth Allen, Aaron Mabuza, Lesley Workman, Ray Magagula, Gerdalize Kok, Craig Davies, Gillian Malatje, Philippe J. Guérin, Mehul Dhorda, Richard J. Maude, Jaishree Raman, Karen I. Barnes
Published 2022

Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in Plasmodium vivax from Thailand, Lao PDR and Cambodia

by Jureeporn Duanguppama, Vivek Bhakta Mathema, Rupam Tripura, Nicholas P.J. Day, Mayfong Maxay, Chea Nguon, Lorenz Von Seidlein, Mehul Dhorda, Thomas J. Peto, Francois Nosten, Nicholas J. White, Arjen M. Dondorp, Mallika Imwong
Published 2020

Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: Implications for prevention, treatment and elimination strategies

by Rupam Tripura, Thomas J. Peto, Jeremy Chalk, Sue J. Lee, Pasathorn Sirithiranont, Chea Nguon, Mehul Dhorda, Lorenz Von Seidlein, Richard J. Maude, Nicholas P.J. Day, Mallika Imwong, Nicholas J. White, Arjen M. Dondorp
Published 2018

Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: implications for prevention, treatment and elimination strategies

by Rupam Tripura, Peto, Thomas J., Jeremy Chalk, Lee, Sue J., Pasathorn Sirithiranont, Chea Nguon, Mehul Dhorda, Seidlein, Lorenz von, Maude, Richard J., Day, Nicholas P. J., Mallika Imwong, White, Nicholas J., Dondorp, Arjen M.
Published 2017

Ethical, Regulatory and Market related aspects of Deploying Triple Artemisinin-Based Combination Therapies for Malaria treatment in Africa: A study protocol.

by Paulina Tindana, Freek de Haan, Olugbenga Ayodeji Mokuolu, Rosemonde Guissou, Oladimeji Akeem Bolarinwa, Jean Bosco Ouedraogo, Fatoumata Tou, Wouter P.C. Boon, Ellen H.M. Moors, Arjen M. Dondorp, Mehul Dhorda, Chanaki Amaratunga, Phaik Yeong Cheah
Published 2022

To what extent are the antimalarial markets in African countries ready for a transition to triple artemisinin-based combination therapies?

by Freek De Haan, Oladimeji Akeem Bolarinwa, Rosemonde Guissou, Fatoumata Tou, Paulina Tindana, Wouter P.C. Boon, Ellen H.M. Moors, Phaik Yeong Cheah, Mehul Dhorda, Arjen M. Dondorp, Jean Bosco Ouedraogo, Olugbenga A. Mokuolu, Chanaki Amaratunga
Published 2022

Association between subclinical malaria infection and inflammatory host response in a pre-elimination setting

by Thomas J. Peto, Rupam Tripura, Sue J. Lee, Thomas Althaus, Susanna Dunachie, Chea Nguon, Mehul Dhorda, Cholrawee Promnarate, Jeremy Chalk, Mallika Imwong, Lorenz Von Seidlein, Nicholas P. Day, Arjen M. Dondorp, Nicholas J. White, Yoel Lubell
Published 2018