Artemisinin and multidrug-resistant Plasmodium falciparum - a threat for malaria control and elimination

by Mehul Dhorda, Chanaki Amaratunga, Arjen M. Dondorp
Published 2022

Triple Artemisinin-Based Combination Therapies for Malaria – A New Paradigm?

by Rob W. van der Pluijm, Chanaki Amaratunga, Mehul Dhorda, Arjen M. Dondorp
Published 2020

Expert perspectives on the introduction of Triple Artemisinin-based Combination Therapies (TACTs) in Southeast Asia: a Delphi study

by Freek de Haan, Wouter P.C. Boon, Chanaki Amaratunga, Arjen M. Dondorp
Published 2022

Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro

by Chanaki Amaratunga, Benoit Witkowski, Dalin Dek, Vorleak Try, Nimol Khim, Olivo Miotto, Didier Ménard, Rick M. Fairhurst
Published 2018

Deploying triple artemisinin-based combination therapy (TACT) for malaria treatment in Africa: ethical and practical considerations

by Paulina Tindana, Freek de Haan, Chanaki Amaratunga, Mehul Dhorda, Rob W. van der Pluijm, Arjen M. Dondorp, Phaik Yeong Cheah
Published 2022

Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2/3 copy number variation in Plasmodium falciparum

by Megan R. Ansbro, Christopher G. Jacob, Roberto Amato, Mihir Kekre, Chanaki Amaratunga, Sokunthea Sreng, Seila Suon, Olivo Miotto, Rick M. Fairhurst, Thomas E. Wellems, Dominic P. Kwiatkowski
Published 2020

Artemisinin-resistant Plasmodium falciparum clinical isolates can infect diverse mosquito vectors of Southeast Asia and Africa

by Brandyce St. Laurent, Becky Miller, Timothy A. Burton, Chanaki Amaratunga, Sary Men, Siv Sovannaroth, Michael P. Fay, Olivo Miotto, Robert W. Gwadz, Jennifer M. Anderson, Rick M. Fairhurst
Published 2018

Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study

by Roberto Amato, Richard D. Pearson, Jacob Almagro-Garcia, Chanaki Amaratunga, Pharath Lim, Seila Suon, Sokunthea Sreng, Eleanor Drury, Jim Stalker, Olivo Miotto, Rick M. Fairhurst, Dominic P. Kwiatkowski
Published 2019

Ethical, Regulatory and Market related aspects of Deploying Triple Artemisinin-Based Combination Therapies for Malaria treatment in Africa: A study protocol.

by Paulina Tindana, Freek de Haan, Olugbenga Ayodeji Mokuolu, Rosemonde Guissou, Oladimeji Akeem Bolarinwa, Jean Bosco Ouedraogo, Fatoumata Tou, Wouter P.C. Boon, Ellen H.M. Moors, Arjen M. Dondorp, Mehul Dhorda, Chanaki Amaratunga, Phaik Yeong Cheah
Published 2022

To what extent are the antimalarial markets in African countries ready for a transition to triple artemisinin-based combination therapies?

by Freek De Haan, Oladimeji Akeem Bolarinwa, Rosemonde Guissou, Fatoumata Tou, Paulina Tindana, Wouter P.C. Boon, Ellen H.M. Moors, Phaik Yeong Cheah, Mehul Dhorda, Arjen M. Dondorp, Jean Bosco Ouedraogo, Olugbenga A. Mokuolu, Chanaki Amaratunga
Published 2022

Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia

by Angana Mukherjee, Selina Bopp, Pamela Magistrado, Wesley Wong, Rachel Daniels, Allison Demas, Stephen Schaffner, Chanaki Amaratunga, Pharath Lim, Mehul Dhorda, Olivo Miotto, Charles Woodrow, Elizabeth A. Ashley, Arjen M. Dondorp, Nicholas J. White, Dyann Wirth, Rick Fairhurst, Sarah K. Volkman
Published 2018

Plasmepsin II-III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum

by Selina Bopp, Pamela Magistrado, Wesley Wong, Stephen F. Schaffner, Angana Mukherjee, Pharath Lim, Mehul Dhorda, Chanaki Amaratunga, Charles J. Woodrow, Elizabeth A. Ashley, Nicholas J. White, Arjen M. Dondorp, Rick M. Fairhurst, Frederic Ariey, Didier Menard, Dyann F. Wirth, Sarah K. Volkman
Published 2019

Ex Vivo Susceptibility of Plasmodium falciparum to antimalarial drugs in western, Northern, and Eastern Cambodia, 2011-2012: Association with molecular markers

by Pharath Lim, Dalin Dek, Vorleak Try, Richard T. Eastman, Sophy Chy, Sokunthea Sreng, Seila Suon, Sivanna Mao, Chantha Sopha, Baramey Sam, Elizabeth A. Ashley, Olivo Miotto, Arjen M. Dondorp, Nicholas J. White, Xin Zhuan Su, Meng Chuor Char, Jennifer M. Anderson, Chanaki Amaratunga, Didier Menard, Rick M. Fairhurst
Published 2018

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: A parasite clearance rate study

by Chanaki Amaratunga, Sokunthea Sreng, Seila Suon, Erika S. Phelps, Kasia Stepniewska, Pharath Lim, Chongjun Zhou, Sivanna Mao, Jennifer M. Anderson, Niklas Lindegardh, Hongying Jiang, Jianping Song, Xin zhuan Su, Nicholas J. White, Arjen M. Dondorp, Tim J C Anderson, Michael P. Fay, Jianbing Mu, Socheat Duong, Rick M. Fairhurst
Published 2018

Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives

by Katherine O'Flaherty, Ricardo Ataíde, Sophie G. Zaloumis, Elizabeth A. Ashley, Rosanna Powell, Gaoqian Feng, Linda Reiling, Arjen M. Dondorp, Nicholas P. Day, Mehul Dhorda, Rick M. Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tran Tinh Hien, Ye Htut, Mayfong Mayxay, M. Abul Faiz, James G. Beeson, Francois Nosten, Julie A. Simpson, Nicholas J. White, Freya J.I. Fowkes
Published 2020

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

by Frédéric Ariey, Benoit Witkowski, Chanaki Amaratunga, Johann Beghain, Anne Claire Langlois, Nimol Khim, Saorin Kim, Valentine Duru, Christiane Bouchier, Laurence Ma, Pharath Lim, Rithea Leang, Socheat Duong, Sokunthea Sreng, Seila Suon, Char Meng Chuor, Denis Mey Bout, Sandie Ménard, William O. Rogers, Blaise Genton, Thierry Fandeur, Olivo Miotto, Pascal Ringwald, Jacques Le Bras, Antoine Berry, Jean Christophe Barale, Rick M. Fairhurst, Françoise Benoit-Vical, Odile Mercereau-Puijalon, Didier Ménard
Published 2018

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay.

by Campino, Susana, Auburn, Sarah, Kivinen, Katja, Zongo, Issaka, Ouedraogo, Jean-Bosco, Mangano, Valentina, Djimde, Abdoulaye, Doumbo, Ogobara K., Kiara, Steven M., Nzila, Alexis, Borrmann, Steffen, Marsh, Kevin, Michon, Pascal, Mueller, Ivo, Siba, Peter, Jiang, Hongying, Su, Xin-Zhuan, Chanaki Amaratunga, Socheat, Duong, Fairhurst, Rick M., Mallika Imwong, มัลลิกา อิ่มวงศ์, Anderson, Timothy, Nosten, Francois, White, Nicholas J., Gwilliam, Rhian, Deloukas, Panos, MacInnis, Bronwyn, Newbold, Christopher I., Rockett, Kirk, Clark, Taane G., Kwiatkowski, Dominic P.
Published 2012

Population genetic analysis of plasmodium falciparum parasites using a customized illumina goldengate genotyping assay

by Susana Campino, Sarah Auburn, Katja Kivinen, Issaka Zongo, Jean Bosco Ouedraogo, Valentina Mangano, Abdoulaye Djimde, Ogobara K. Doumbo, Steven M. Kiara, Alexis Nzila, Steffen Borrmann, Kevin Marsh, Pascal Michon, Ivo Mueller, Peter Siba, Hongying Jiang, Xin Zhuan Su, Chanaki Amaratunga, Duong Socheat, Rick M. Fairhurst, Mallika Imwong, Timothy Anderson, François Nosten, Nicholas J. White, Rhian Gwilliam, Panos Deloukas, Bronwyn MacInnis, Christopher I. Newbold, Kirk Rockett, Taane G. Clark, Dominic P. Kwiatkowski
Published 2018

Anti-Gametocyte Antigen Humoral Immunity and Gametocytemia During Treatment of Uncomplicated Falciparum Malaria: A Multi-National Study

by Katherine O’Flaherty, Jo Anne Chan, Julia C. Cutts, Sophie G. Zaloumis, Elizabeth A. Ashley, Aung Pyae Phyo, Damien R. Drew, Arjen M. Dondorp, Nicholas P. Day, Mehul Dhorda, Rick M. Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tran Tinh Hien, Ye Htut, Mayfong Mayxay, M. Abul Faiz, Olugbenga A. Mokuolu, Marie A. Onyamboko, Caterina Fanello, Eizo Takashima, Takafumi Tsuboi, Michael Theisen, Francois Nosten, James G. Beeson, Julie A. Simpson, Nicholas J. White, Freya J.I. Fowkes
Published 2022

Evolution of multidrug resistance in plasmodium falciparum: A longitudinal study of genetic resistance markers in the greater mekong subregion

by Mallika Imwong, Kanokon Suwannasin, Suttipat Srisutham, Ranitha Vongpromek, Cholrawee Promnarate, Aungkana Saejeng, Aung Pyae Phyo, Stephane Proux, Tiengkham Pongvongsa, Nguon Chea, Olivo Miotto, Rupam Tripura, Chau Nguyen Hoang, Lek Dysoley, Nghia Ho Dang Trung, Thomas J. Peto, James J. Callery, Rob W. Van der Pluijm, Chanaki Amaratunga, Mavuto Mukaka, Lorenz Von Seidlein, Mayfong Mayxay, Nguyen Thanh Thuy-Nhien, Paul N. Newton, Nicholas P.J. Day, Elizabeth A. Ashley, Francois H. Nosten, Frank M. Smithuis, Mehul Dhorda, Nicholas J. White, Arjen M. Dondorp
Published 2022