Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro

by Chanaki Amaratunga, Benoit Witkowski, Dalin Dek, Vorleak Try, Nimol Khim, Olivo Miotto, Didier Ménard, Rick M. Fairhurst
Published 2018

Artemisinin-resistant Plasmodium falciparum K13 mutant alleles, Thailand-Myanmar border

by Mikael Boullé, Benoit Witkowski, Valentine Duru, Kanlaya Sriprawat, Shalini K. Nair, Marina McDew-White, Tim J.C. Anderson, Aung Pyae Phyo, Didier Menard, François Nosten
Published 2018

Evidence of plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia: Dihydroartemisinin-piperaquine open-label multicenter clinical as...

by Rithea Leang, Walter R.J. Taylor, Denis Mey Bouth, Lijiang Song, Joel Tarning, Meng Chuor Char, Saorin Kim, Benoit Witkowski, Valentine Duru, Anais Domergue, Nimol Khim, Pascal Ringwald, Didier Menard
Published 2018

Reduced artemisinin susceptibility of plasmodium falciparum ring stages in western cambodia

by Benoit Witkowski, Nimol Khim, Pheaktra Chim, Saorin Kim, Sopheakvatey Ke, Nimol Kloeung, Sophy Chy, Socheat Duong, Rithea Leang, Pascal Ringwald, Arjen M. Dondorp, Rupam Tripura, Francoise Benoit-Vical, Antoine Berry, Olivier Gorgette, Frédéric Ariey, Jean Christophe Barale, Odile Mercereau-Puijalon, Didier Menard
Published 2018

Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12)

by Yuxiang Dong, Yogesh Sonawane, Steven P. Maher, Anne Marie Zeeman, Victor Chaumeau, Amélie Vantaux, Caitlin A. Cooper, Francis C.K. Chiu, Eileen Ryan, Jenna McLaren, Gong Chen, Sergio Wittlin, Benoît Witkowski, François Nosten, Kamaraj Sriraghavan, Dennis E. Kyle, Clemens H.M. Kocken, Susan A. Charman, Jonathan L. Vennerstrom
Published 2022

Histone methyltransferase inhibitors are orally bioavailable, fast- Acting molecules with activity against different species causing malaria in humans

by Nicholas A. Malmquist, Sandeep Sundriyal, Joachim Caron, Patty Chen, Benoit Witkowski, Didier Menard, Rossarin Suwanarusk, Laurent Renia, Francois Nosten, María Belén Jiménez-Díaz, Iñigo Angulo-Barturen, María Santos Martínez, Santiago Ferrer, Laura M. Sanz, Francisco Javier Gamo, Sergio Wittlin, Sandra Duffy, Vicky M. Avery, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Matthew J. Fuchter, Artur Scherf
Published 2018

Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro

by Steven P. Maher, Amélie Vantaux, Victor Chaumeau, Adeline C.Y. Chua, Caitlin A. Cooper, Chiara Andolina, Julie Péneau, Mélanie Rouillier, Zaira Rizopoulos, Sivchheng Phal, Eakpor Piv, Chantrea Vong, Sreyvouch Phen, Chansophea Chhin, Baura Tat, Sivkeng Ouk, Bros Doeurk, Saorin Kim, Sangrawee Suriyakan, Praphan Kittiphanakun, Nana Akua Awuku, Amy J. Conway, Rays H.Y. Jiang, Bruce Russell, Pablo Bifani, Brice Campo, François Nosten, Benoît Witkowski, Dennis E. Kyle
Published 2022

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

by Frédéric Ariey, Benoit Witkowski, Chanaki Amaratunga, Johann Beghain, Anne Claire Langlois, Nimol Khim, Saorin Kim, Valentine Duru, Christiane Bouchier, Laurence Ma, Pharath Lim, Rithea Leang, Socheat Duong, Sokunthea Sreng, Seila Suon, Char Meng Chuor, Denis Mey Bout, Sandie Ménard, William O. Rogers, Blaise Genton, Thierry Fandeur, Olivo Miotto, Pascal Ringwald, Jacques Le Bras, Antoine Berry, Jean Christophe Barale, Rick M. Fairhurst, Françoise Benoit-Vical, Odile Mercereau-Puijalon, Didier Ménard
Published 2018

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

by Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H.I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H.Y. Jiang, Dennis E. Kyle, John H. Adams
Published 2019

Author Correction: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum (Nature Communications (2018) DOI: 10.1038/s41...

by Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H.I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H.Y. Jiang, Dennis E. Kyle, John H. Adams
Published 2019

Optimal health and disease management using spatial uncertainty: A geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast As...

by Eric P.M. Grist, Jennifer A. Flegg, Georgina Humphreys, Ignacio Suay Mas, Tim J.C. Anderson, Elizabeth A. Ashley, Nicholas P.J. Day, Mehul Dhorda, Arjen M. Dondorp, M. Abul Faiz, Peter W. Gething, Tran T. Hien, Tin M. Hlaing, Mallika Imwong, Jean Marie Kindermans, Richard J. Maude, Mayfong Mayxay, Marina McDew-White, Didier Menard, Shalini Nair, Francois Nosten, Paul N. Newton, Ric N. Price, Sasithon Pukrittayakamee, Shannon Takala-Harrison, Frank Smithuis, Nhien T. Nguyen, Kyaw M. Tun, Nicholas J. White, Benoit Witkowski, Charles J. Woodrow, Rick M. Fairhurst, Carol Hopkins Sibley, Philippe J. Guerin
Published 2018