Revisiting the design of phase III clinical trials of antimalarial drugs for uncomplicated Plasmodium falciparum malaria

by Steffen Borrmann, Tim Peto, Robert W. Snow, Win Gutteridge, Nicholas J. White
Published 2018

Declining responsiveness of plasmodium falciparum infections to Artemisinin-Based combination treatments on the Kenyan coast

by Steffen Borrmann, Philip Sasi, Leah Mwai, Mahfudh Bashraheil, Ahmed Abdallah, Steven Muriithi, Henrike Frühauf, Barbara Schaub, Johannes Pfeil, Judy Peshu, Warunee Hanpithakpong, Anja Rippert, Elizabeth Juma, Benjamin Tsofa, Moses Mosobo, Brett Lowe, Faith Osier, Greg Fegan, Niklas Lindegårdh, Alexis Nzila, Norbert Peshu, Margaret Mackinnon, Kevin Marsh
Published 2018

Plasmo View: A web-based resource to visualise global Plasmodium falciparum genomic variation

by Mark D. Preston, Samuel A. Assefa, Harold Ocholla, Colin J. Sutherland, Steffen Borrmann, Alexis Nzila, Pascal Michon, Tran Tinh Hien, Teun Bousema, Christopher J. Drakeley, Issaka Zongo, Jean Bosco Ouédraogo, Abdoulaye A. Djimde, Ogobara K. Doumbo, Francois Nosten, Rick M. Fairhurst, David J. Conway, Cally Roper, Taane G. Clark
Published 2018

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

by Jennifer A. Flegg, Philippe J. Guérin, Francois Nosten, Elizabeth A. Ashley, Aung Pyae Phyo, Arjen M. Dondorp, Rick M. Fairhurst, Duong Socheat, Steffen Borrmann, Anders Björkman, Andreas Mårtensson, Mayfong Mayxay, Paul N. Newton, Delia Bethell, Youry Se, Harald Noedl, Mahamadou Diakite, Abdoulaye A. Djimde, Tran T. Hien, Nicholas J. White, Kasia Stepniewska
Published 2018

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains

by Mark D. Preston, Susana Campino, Samuel A. Assefa, Diego F. Echeverry, Harold Ocholla, Alfred Amambua-Ngwa, Lindsay B. Stewart, David J. Conway, Steffen Borrmann, Pascal Michon, Issaka Zongo, Jean Bosco Ouédraogo, Abdoulaye A. Djimde, Ogobara K. Doumbo, Francois Nosten, Arnab Pain, Teun Bousema, Chris J. Drakeley, Rick M. Fairhurst, Colin J. Sutherland, Cally Roper, Taane G. Clark
Published 2018

Whole-genome scans provide evidence of adaptive evolution in malawian Plasmodium falciparum isolates

by Harold Ocholla, Mark D. Preston, Mwapatsa Mipando, Anja T.R. Jensen, Susana Campino, Bronwyn Macinnis, Daniel Alcock, Anja Terlouw, Issaka Zongo, Jean Bosco Oudraogo, Abdoulaye A. Djimde, Samuel Assefa, Ogobara K. Doumbo, Steffen Borrmann, Alexis Nzila, Kevin Marsh, Rick M. Fairhurst, Francois Nosten, Tim J.C. Anderson, Dominic P. Kwiatkowski, Alister Craig, Taane G. Clark, Jacqui Montgomery
Published 2018

Population genetic analysis of plasmodium falciparum parasites using a customized illumina goldengate genotyping assay

by Susana Campino, Sarah Auburn, Katja Kivinen, Issaka Zongo, Jean Bosco Ouedraogo, Valentina Mangano, Abdoulaye Djimde, Ogobara K. Doumbo, Steven M. Kiara, Alexis Nzila, Steffen Borrmann, Kevin Marsh, Pascal Michon, Ivo Mueller, Peter Siba, Hongying Jiang, Xin Zhuan Su, Chanaki Amaratunga, Duong Socheat, Rick M. Fairhurst, Mallika Imwong, Timothy Anderson, François Nosten, Nicholas J. White, Rhian Gwilliam, Panos Deloukas, Bronwyn MacInnis, Christopher I. Newbold, Kirk Rockett, Taane G. Clark, Dominic P. Kwiatkowski
Published 2018

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

by Frank Kloprogge, Lesley Workman, Steffen Borrmann, Mamadou Tékété, Gilbert Lefèvre, Kamal Hamed, Patrice Piola, Johan Ursing, Poul Erik Kofoed, Andreas Mårtensson, Billy Ngasala, Anders Björkman, Michael Ashton, Sofia Friberg Hietala, Francesca Aweeka, Sunil Parikh, Leah Mwai, Timothy M.E. Davis, Harin Karunajeewa, Sam Salman, Francesco Checchi, Carole Fogg, Paul N. Newton, Mayfong Mayxay, Philippe Deloron, Jean François Faucher, François Nosten, Elizabeth A. Ashley, Rose McGready, Michele van Vugt, Stephane Proux, Ric N. Price, Juntra Karbwang, Farkad Ezzet, Rajesh Bakshi, Kasia Stepniewska, Nicholas J. White, Philippe J. Guerin, Karen I. Barnes, Joel Tarning
Published 2019

Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic respons...

by Elizabeth A. Ashley, Francesca Aweeka, Karen I. Barnes, Quique Bassat, Steffen Borrmann, Prabin Dahal, Timothy M.E. Davis, Mey Bouth Denis, Abdoulaye A. Djimde, Jean François Faucher, Blaise Genton, Philippe J. Guérin, Kamal Hamed, Eva Maria Hodel, Liusheng Huang, Vincent Jullien, Harin A. Karunajeewa, Jean René Kiechel, Poul Erik Kofoed, Gilbert Lefèvre, Niklas Lindegardh Lindegardh, Andreas Mårtensson, Mayfong Mayxay, Rose Mcgready, Clarissa Moreira, Paul N. Newton, Billy E. Ngasala, Francois Nosten, Christian Nsanzabana, Sunil Parikh, Patrice Piola, Ric N. Price, Pascal Ringwald, Lars Rombo, Birgit Schramm, Carol Hopkins Sibley, Kasia Stepniewska, Joel Tarning, Johan Ursing, Michele Van Vugt, Nicholas J. White, Lesley J. Workman, Philippe Deloron, Kevin Marsh
Published 2018

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: An individual patient data meta-analysis

by Salim Abdulla, Elizabeth A. Ashley, Quique Bassat, Delia Bethell, Anders Björkman, Steffen Borrmann, Umberto D’Alessandro, Prabin Dahal, Nicholas P. Day, Mahamadou Diakite, Abdoulaye A. Djimde, Arjen M. Dondorp, Socheat Duong, Michael D. Edstein, Rick M. Fairhurst, M. Abul Faiz, Catherine Falade, Jennifer A. Flegg, Carole Fogg, Raquel Gonzalez, Brian Greenwood, Philippe J. Guérin, Jean Paul Guthmann, Kamal Hamed, Tran Tinh Hien, Ye Htut, Elizabeth Juma, Pharath Lim, Andreas Mårtensson, Mayfong Mayxay, Olugbenga A. Mokuolu, Clarissa Moreira, Paul Newton, Harald Noedl, Francois Nosten, Bernhards R. Ogutu, Marie A. Onyamboko, Seth Owusu-Agyei, Aung Pyae Phyo, Zul Premji, Ric N. Price, Sasithon Pukrittayakamee, Michael Ramharter, Issaka Sagara, Youry Se, Seila Suon, Kasia Stepniewska, Stephen A. Ward, Nicholas J. White, Peter A. Winstanley
Published 2018

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

by Magnus Manske, Olivo Miotto, Susana Campino, Sarah Auburn, Jacob Almagro-Garcia, Gareth Maslen, Jack O'Brien, Abdoulaye Djimde, Ogobara Doumbo, Issaka Zongo, Jean Bosco Ouedraogo, Pascal Michon, Ivo Mueller, Peter Siba, Alexis Nzila, Steffen Borrmann, Steven M. Kiara, Kevin Marsh, Hongying Jiang, Xin Zhuan Su, Chanaki Amaratunga, Rick Fairhurst, Duong Socheat, Francois Nosten, Mallika Imwong, Nicholas J. White, Mandy Sanders, Elisa Anastasi, Dan Alcock, Eleanor Drury, Samuel Oyola, Michael A. Quail, Daniel J. Turner, Valentin Ruano-Rubio, Dushyanth Jyothi, Lucas Amenga-Etego, Christina Hubbart, Anna Jeffreys, Kate Rowlands, Colin Sutherland, Cally Roper, Valentina Mangano, David Modiano, John C. Tan, Michael T. Ferdig, Alfred Amambua-Ngwa, David J. Conway, Shannon Takala-Harrison, Christopher V. Plowe, Julian C. Rayner, Kirk A. Rockett, Taane G. Clark, Chris I. Newbold, Matthew Berriman, Bronwyn MacInnis, Dominic P. Kwiatkowski
Published 2018

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: Parasite risk factors that affect treatment outcomes for P. falciparum m...

by Meera Venkatesan, Nahla B. Gadalla, Kasia Stepniewska, Prabin Dahal, Christian Nsanzabana, Clarissa Moriera, Ric N. Price, Andreas Ma˚rtensson, Philip J. Rosenthal, Grant Dorsey, Colin J. Sutherland, Philippe Guérin, Timothy M.E. Davis, Didier Ménard, Ishag Adam, George Ademowo, Cesar Arze, Frederick N. Baliraine, Nicole Berens-Riha, Anders Björkman, Steffen Borrmann, Francesco Checchi, Meghna Desai, Mehul Dhorda, Abdoulaye A. Djimdé, Badria B. El-Sayed, Teferi Eshetu, Frederick Eyase, Catherine Falade, Jean Franc¸ois Faucher, Gabrielle Fröberg, Anastasia Grivoyannis, Sally Hamour, Sandrine Houzé, Jacob Johnson, Erasmus Kamugisha, Simon Kariuki, Jean René Kiechel, Fred Kironde, Poul Erik Kofoed, Jacques LeBras, Maja Malmberg, Leah Mwai, Billy Ngasala, Francois Nosten, Samuel L. Nsobya, Alexis Nzila, Mary Oguike, Sabina Dahlström Otienoburu, Bernhards Ogutu, Jean Bosco Ouédraogo, Patrice Piola, Lars Rombo, Birgit Schramm, A. Fabrice Somé, Julie Thwing, Johan Ursing, Rina P.M. Wong, Ahmed Zeynudin, Issaka Zongo, Christopher V. Plowe, Carol Hopkins Sibley
Published 2018

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: A meta-analysis of individual patient data

by Martin A. Adjuik, Richard Allan, Anupkumar R. Anvikar, Elizabeth A. Ashley, Mamadou S. Ba, Hubert Barennes, Karen I. Barnes, Quique Bassat, Elisabeth Baudin, Anders Björkman, François Bompart, Maryline Bonnet, Steffen Borrmann, Philippe Brasseur, Hasifa Bukirwa, Francesco Checchi, Michel Cot, Prabin Dahal, Umberto D'Alessandro, Philippe Deloron, Meghna Desai, Graciela Diap, Abdoulaye A. Djimde, Grant Dorsey, Ogobara K. Doumbo, Emmanuelle Espié, Jean Francois Etard, Caterina I. Fanello, Jean François Faucher, Babacar Faye, Jennifer A. Flegg, Oumar Gaye, Peter W. Gething, Raquel González, Francesco Grandesso, Philippe J. Guerin, Jean Paul Guthmann, Sally Hamour, Armedy Ronny Hasugian, Simon I. Hay, Georgina S. Humphreys, Vincent Jullien, Elizabeth Juma, Moses R. Kamya, Corine Karema, Jean R. Kiechel, Peter G. Kremsner, Sanjeev Krishna, Valérie Lameyre, Laminou M. Ibrahim, Sue J. Lee, Bertrand Lell, Andreas Martensson, Achille Massougbodji, Hervé Menan, Didier Ménard, Clara Menéndez, Martin Meremikwu, Clarissa Moreira, Carolyn Nabasumba, Michael Nambozi, Jean Louis Ndiaye, Frederic Nikiema, Christian Nsanzabana, Francine Ntoumi, Bernhards R. Ogutu, Piero Olliaro, Lyda Osorio, Jean Bosco Ouédraogo, Louis K. Penali, Mbaye Pene
Published 2018

The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data

by Jane Achan, Ishag Adam, Emmanuel Arinaitwe, Elizabeth A. Ashley, Ghulam Rahim Awab, Mamadou S. Ba, Karen I. Barnes, Quique Bassat, Steffen Borrmann, Teun Bousema, Prabin Dahal, Umberto D'Alessandro, Timothy M.E. Davis, Arjen M. Dondorp, Grant Dorsey, Chris J. Drakeley, Caterina I. Fanello, Babacar Faye, Jennifer A. Flegg, Oumar Gaye, Peter W. Gething, Raquel González, Philippe J. Guerin, Simon I. Hay, Tran T. Hien, Bart Janssens, Moses R. Kamya, Corine Karema, Harin A. Karunajeewa, Moussa Koné, Bertrand Lell, Kevin Marsh, Mayfong Mayxay, Clara Menéndez, Petra F. Mens, Martin Meremikwu, Clarissa Moreira, Ivo Mueller, Carolyn Nabasumba, Michael Nambozi, Jean Louis Ndiaye, Paul N. Newton, Thuy Nhien Nguyen, Francois Nosten, Christian Nsanzabana, Sabah A. Omar, Jean Bosco Ouédraogo, Louis K. Penali, Mbaye Pene, Aung Pyae Phyo, Patrice Piola, Ric N. Price, P. Sasithon, Philip J. Rosenthal, Albert Same-Ekobo, Patrick Sawa, Henk D.F.H. Schallig, Seif A. Shekalaghe, Carol Hopkins Sibley, Jeff Smith, Frank Smithuis, Anyirékun Fabrice Somé, Kasia Stepniewska, Ambrose O. Talisuna, Joel Tarning, Emiliana Tjitra, Roger C.K. Tine
Published 2018

Genomic epidemiology of artemisinin resistant malaria

by Roberto Amato, Olivo Miotto, Charles J. Woodrow, Jacob Almagro-Garcia, Ipsita Sinha, Susana Campino, Daniel Mead, Eleanor Drury, Mihir Kekre, Mandy Sanders, Alfred Amambua-Ngwa, Chanaki Amaratunga, Lucas Amenga-Etego, Voahangy Andrianaranjaka, Tobias Apinjoh, Elizabeth Ashley, Sarah Auburn, Gordon A. Awandare, Vito Baraka, Alyssa Barry, Maciej F. Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter C. Bull, Kesinee Chotivanich, David J. Conway, Alister Craig, Nicholas P. Day, Abdoulaye Djimdé, Christiane Dolecek, Arjen M. Dondorp, Chris Drakeley, Patrick Duffy, Diego F. Echeverry, Thomas G. Egwang, Rick M. Fairhurst, Abul Faiz, Caterina I. Fanello, Tran Tinh Hien, Abraham Hodgson, Mallika Imwong, Deus Ishengoma, Pharath Lim, Chanthap Lon, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Pascal Michon, Victor Mobegi, Olugbenga A. Mokuolu, Jacqui Montgomery, Ivo Mueller, Myat Phone Kyaw, Paul N. Newton, Francois Nosten, Rintis Noviyanti, Alexis Nzila, Harold Ocholla, Abraham Oduro, Marie Onyamboko, Jean Bosco Ouedraogo, Aung Pyae P. Phyo, Christopher Plowe, Ric N. Price, Sasithon Pukrittayakamee, Milijaona Randrianarivelojosia, Pascal Ringwald, Lastenia Ruiz, David Saunders, Alex Shayo, Peter Siba, Shannon Takala-Harrison, Thuy Nhien N. Thanh, Vandana Thathy, Federica Verra, Jason Wendler
Published 2018

Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: A literature review and meta-analysis of individual patie...

by Salim Abdulla, Ishag Adam, George O. Adjei, Martin A. Adjuik, Bereket Alemayehu, Richard Allan, Emmanuel Arinaitwe, Elizabeth A. Ashley, Mamadou S. Ba, Hubert Barennes, Karen I. Barnes, Quique Bassat, Elisabeth Baudin, Nicole Berens-Riha, Anders Björkman, François Bompart, Maryline Bonnet, Steffen Borrmann, Teun Bousema, Philippe Brasseur, Hasifa Bukirwa, Francesco Checchi, Prabin Dahal, Umberto D'Alessandro, Meghna Desai, Alassane Dicko, Abdoulaye A. Djimdé, Grant Dorsey, Ogobara K. Doumbo, Chris J. Drakeley, Stephan Duparc, Teferi Eshetu, Emmanuelle Espié, Jean François Etard, Abul M. Faiz, Catherine O. Falade, Caterina I. Fanello, Jean François Faucher, Babacar Faye, Oumar Faye, Scott Filler, Jennifer A. Flegg, Bakary Fofana, Carole Fogg, Nahla B. Gadalla, Oumar Gaye, Blaise Genton, Peter W. Gething, José P. Gil, Raquel González, Francesco Grandesso, Bryan Greenhouse, Brian Greenwood, Anastasia Grivoyannis, Philippe J. Guerin, Jean Paul Guthmann, Kamal Hamed, Sally Hamour, Simon I. Hay, Eva Maria Hodel, Georgina S. Humphreys, Jimee Hwang, Maman L. Ibrahim, Daddi Jima, Joel J. Jones, Vincent Jullien, Elizabeth Juma, Patrick S. Kachur, Piet A. Kager, Erasmus Kamugisha, Moses R. Kamya, Corine Karema
Published 2018

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

by Malaria Gen, Ambroise Ahouidi, Mozam Ali, Jacob Almagro-Garcia, Alfred Amambua-Ngwa, Chanaki Amaratunga, Roberto Amato, Lucas Amenga-Etego, Ben Andagalu, Tim J.C. Anderson, Voahangy Andrianaranjaka, Tobias Apinjoh, Cristina Ariani, Elizabeth A. Ashley, Sarah Auburn, Gordon A. Awandare, Hampate Ba, Vito Baraka, Alyssa E. Barry, Philip Bejon, Gwladys I. Bertin, Maciej F. Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter C. Bull, George B.J. Busby, Thanat Chookajorn, Kesinee Chotivanich, Antoine Claessens, David Conway, Alister Craig, Umberto D'Alessandro, Souleymane Dama, Nicholas PJ Day, Brigitte Denis, Mahamadou Diakite, Abdoulaye Djimdé, Christiane Dolecek, Arjen M. Dondorp, Chris Drakeley, Eleanor Drury, Patrick Duffy, Diego F. Echeverry, Thomas G. Egwang, Berhanu Erko, Rick M. Fairhurst, Abdul Faiz, Caterina A. Fanello, Mark M. Fukuda, Dionicia Gamboa, Anita Ghansah, Lemu Golassa, Sonia Goncalves, William L. Hamilton, G. L.Abby Harrison, Lee Hart, Christa Henrichs, Tran Tinh Hien, Catherine A. Hill, Abraham Hodgson, Christina Hubbart, Mallika Imwong, Deus S. Ishengoma, Scott A. Jackson, Chris G. Jacob, Ben Jeffery, Anna E. Jeffreys, Kimberly J. Johnson, Dushyanth Jyothi, Claire Kamaliddin, Edwin Kamau, Mihir Kekre, Krzysztof Kluczynski, Theerarat Kochakarn, Abibatou Konaté, Dominic P. Kwiatkowski, Myat Phone Kyaw, Pharath Lim, Chanthap Lon, Kovana M. Loua, Oumou Maïga-Ascofaré, Cinzia Malangone, Magnus Manske, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Alistair Miles, Olivo Miotto, Victor Mobegi, Olugbenga A. Mokuolu, Jacqui Montgomery, Ivo Mueller, Paul N. Newton, Thuy Nguyen, Thuy Nhien Nguyen, Harald Noedl, François Nosten, Rintis Noviyanti, Alexis Nzila
Published 2022

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

by Ambroise Ahouidi, Mozam Ali, Jacob Almagro-Garcia, Alfred Amambua-Ngwa, Chanaki Amaratunga, Roberto Amato, Lucas Amenga-Etego, Ben Andagalu, Tim J.C. Anderson, Voahangy Andrianaranjaka, Tobias Apinjoh, Cristina Ariani, Elizabeth A. Ashley, Sarah Auburn, Gordon Awandare, Hampate Ba, Vito Baraka, Alyssa E. Barry, Philip Bejon, Gwladys I. Bertin, Maciej F. Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter C. Bull, George B.J. Busby, Thanat Chookajorn, Kesinee Chotivanich, Antoine Claessens, David Conway, Alister Craig, Umberto D'Alessandro, Souleymane Dama, Nicholas P.J. Day, Brigitte Denis, Mahamadou Diakite, Abdoulaye Djimdé, Christiane Dolecek, Arjen M. Dondorp, Chris Drakeley, Eleanor Drury, Patrick Duffy, Diego F. Echeverry, Thomas G. Egwang, Berhanu Erko, Rick M. Fairhurst, Abdul Faiz, Caterina A. Fanello, Mark M. Fukuda, Dionicia Gamboa, Anita Ghansah, Lemu Golassa, Sonia Goncalves, William L. Hamilton, G. L.Abby Harrison, Lee Hart, Christa Henrichs, Tran Tinh Hien, Catherine A. Hill, Abraham Hodgson, Christina Hubbart, Mallika Imwong, Deus S. Ishengoma, Scott A. Jackson, Chris G. Jacob, Ben Jeffery, Anna E. Jeffreys, Kimberly J. Johnson, Dushyanth Jyothi, Claire Kamaliddin, Edwin Kamau, Mihir Kekre, Krzysztof Kluczynski, Theerarat Kochakarn, Abibatou Konaté, Dominic P. Kwiatkowski, Myat Phone Kyaw, Pharath Lim, Chanthap Lon, Kovana M. Loua, Oumou Maïga-Ascofaré, Cinzia Malangone, Magnus Manske, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Alistair Miles, Olivo Miotto, Victor Mobegi, Olugbenga A. Mokuolu, Jacqui Montgomery, Ivo Mueller, Paul N. Newton, Thuy Nguyen, Thuy Nhien Nguyen, Harald Noedl, Francois Nosten, Rintis Noviyanti, Alexis Nzila, Lynette I. Ochola-Oyier
Published 2022