Plasmodium falciparum drug resistance phenotype as assessed by patient antimalarial drug levels and its association with pfmdr1 polymorphisms

by Maja Malmberg, Pedro E. Ferreira, Joel Tarning, Johan Ursing, Billy Ngasala, Anders Björkman, Andreas Mårtensson, José P. Gil
Published 2018

Population pharmacokinetics and pharmacodynamics of artemether and lumefantrine during combination treatment in children with uncomplicated falciparum malaria in Tanzania

by Sofia Friberg Hietala, Andreas Mårtensson, Billy Ngasala, Sabina Dahlström, Niklas Lindegårdh, Anna Annerberg, Zul Premji, Anna Färnert, Pedro Gil, Anders Björkman, Michael Ashton
Published 2018

Single nucleotide polymorphisms in Plasmodium falciparum V type H⁺pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms

by Irina Tatiana Jovel, Pedro Eduardo Ferreira, Maria Isabel Veiga, Maja Malmberg, Andreas Mårtensson, Akira Kaneko, Sedigheh Zakeri, Claribel Murillo, Francois Nosten, Anders Björkman, Johan Ursing
Published 2018

A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting - High coverage and safety, but no significant impact...

by Ulrika Morris, Mwinyi I. Msellem, Humphrey Mkali, Atiqul Islam, Berit Aydin-Schmidt, Irina Jovel, Shija Joseph Shija, Mwinyi Khamis, Safia Mohammed Ali, Lamija Hodzic, Ellinor Magnusson, Eugenie Poirot, Adam Bennett, Michael C. Sachs, Joel Tarning, Andreas Mårtensson, Abdullah S. Ali, Anders Björkman
Published 2019

Arterolane, a new synthetic trioxolane for treatment of uncomplicated Plasmodium falciparum malaria: A phase II, multicenter, randomized, dose-finding clinical trial

by Neena Valecha, Sornchai Looareesuwan, Andreas Martensson, Salim Mohammed Abdulla, Srivicha Krudsood, Noppadon Tangpukdee, Sanjib Mohanty, Saroj K. Mishra, P. K. Tyagi, S. K. Sharma, Joerg Moehrle, Anirudh Gautam, Arjun Roy, Jyoti K. Paliwal, Monica Kothari, Nilanjan Saha, Aditya P. Dash, Anders Björkman
Published 2018

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

by Jennifer A. Flegg, Philippe J. Guérin, Francois Nosten, Elizabeth A. Ashley, Aung Pyae Phyo, Arjen M. Dondorp, Rick M. Fairhurst, Duong Socheat, Steffen Borrmann, Anders Björkman, Andreas Mårtensson, Mayfong Mayxay, Paul N. Newton, Delia Bethell, Youry Se, Harald Noedl, Mahamadou Diakite, Abdoulaye A. Djimde, Tran T. Hien, Nicholas J. White, Kasia Stepniewska
Published 2018

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

by Frank Kloprogge, Lesley Workman, Steffen Borrmann, Mamadou Tékété, Gilbert Lefèvre, Kamal Hamed, Patrice Piola, Johan Ursing, Poul Erik Kofoed, Andreas Mårtensson, Billy Ngasala, Anders Björkman, Michael Ashton, Sofia Friberg Hietala, Francesca Aweeka, Sunil Parikh, Leah Mwai, Timothy M.E. Davis, Harin Karunajeewa, Sam Salman, Francesco Checchi, Carole Fogg, Paul N. Newton, Mayfong Mayxay, Philippe Deloron, Jean François Faucher, François Nosten, Elizabeth A. Ashley, Rose McGready, Michele van Vugt, Stephane Proux, Ric N. Price, Juntra Karbwang, Farkad Ezzet, Rajesh Bakshi, Kasia Stepniewska, Nicholas J. White, Philippe J. Guerin, Karen I. Barnes, Joel Tarning
Published 2019

Efficacy of Single-Dose Primaquine with Artemisinin Combination Therapy on Plasmodium falciparum Gametocytes and Transmission: An Individual Patient Meta-Analysis

by Kasia Stepniewska, Georgina S. Humphreys, Bronner P. Gonçalves, Elaine Craig, Roly Gosling, Philippe J. Guerin, Ric N. Price, Karen I. Barnes, Jaishree Raman, Menno R. Smit, Umberto D'Alessandro, Will J.R. Stone, Anders Bjorkman, Aaron M. Samuels, Maria I. Arroyo-Arroyo, Guido J.H. Bastiaens, Joelle M. Brown, Alassane Dicko, Badria B. El-Sayed, Salah Eldin G. Elzaki, Alice C. Eziefula, Simon Kariuki, Titus K. Kwambai, Amanda E. Maestre, Andreas Martensson, Dominic Mosha, Richard O. Mwaiswelo, Billy E. Ngasala, Joseph Okebe, Michelle E. Roh, Patrick Sawa, Alfred B. Tiono, Ingrid Chen, Chris J. Drakeley, Teun Bousema
Published 2022

Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic respons...

by Elizabeth A. Ashley, Francesca Aweeka, Karen I. Barnes, Quique Bassat, Steffen Borrmann, Prabin Dahal, Timothy M.E. Davis, Mey Bouth Denis, Abdoulaye A. Djimde, Jean François Faucher, Blaise Genton, Philippe J. Guérin, Kamal Hamed, Eva Maria Hodel, Liusheng Huang, Vincent Jullien, Harin A. Karunajeewa, Jean René Kiechel, Poul Erik Kofoed, Gilbert Lefèvre, Niklas Lindegardh Lindegardh, Andreas Mårtensson, Mayfong Mayxay, Rose Mcgready, Clarissa Moreira, Paul N. Newton, Billy E. Ngasala, Francois Nosten, Christian Nsanzabana, Sunil Parikh, Patrice Piola, Ric N. Price, Pascal Ringwald, Lars Rombo, Birgit Schramm, Carol Hopkins Sibley, Kasia Stepniewska, Joel Tarning, Johan Ursing, Michele Van Vugt, Nicholas J. White, Lesley J. Workman, Philippe Deloron, Kevin Marsh
Published 2018

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: An individual patient data meta-analysis

by Salim Abdulla, Elizabeth A. Ashley, Quique Bassat, Delia Bethell, Anders Björkman, Steffen Borrmann, Umberto D’Alessandro, Prabin Dahal, Nicholas P. Day, Mahamadou Diakite, Abdoulaye A. Djimde, Arjen M. Dondorp, Socheat Duong, Michael D. Edstein, Rick M. Fairhurst, M. Abul Faiz, Catherine Falade, Jennifer A. Flegg, Carole Fogg, Raquel Gonzalez, Brian Greenwood, Philippe J. Guérin, Jean Paul Guthmann, Kamal Hamed, Tran Tinh Hien, Ye Htut, Elizabeth Juma, Pharath Lim, Andreas Mårtensson, Mayfong Mayxay, Olugbenga A. Mokuolu, Clarissa Moreira, Paul Newton, Harald Noedl, Francois Nosten, Bernhards R. Ogutu, Marie A. Onyamboko, Seth Owusu-Agyei, Aung Pyae Phyo, Zul Premji, Ric N. Price, Sasithon Pukrittayakamee, Michael Ramharter, Issaka Sagara, Youry Se, Seila Suon, Kasia Stepniewska, Stephen A. Ward, Nicholas J. White, Peter A. Winstanley
Published 2018

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: A meta-analysis of individual patient data

by Martin A. Adjuik, Richard Allan, Anupkumar R. Anvikar, Elizabeth A. Ashley, Mamadou S. Ba, Hubert Barennes, Karen I. Barnes, Quique Bassat, Elisabeth Baudin, Anders Björkman, François Bompart, Maryline Bonnet, Steffen Borrmann, Philippe Brasseur, Hasifa Bukirwa, Francesco Checchi, Michel Cot, Prabin Dahal, Umberto D'Alessandro, Philippe Deloron, Meghna Desai, Graciela Diap, Abdoulaye A. Djimde, Grant Dorsey, Ogobara K. Doumbo, Emmanuelle Espié, Jean Francois Etard, Caterina I. Fanello, Jean François Faucher, Babacar Faye, Jennifer A. Flegg, Oumar Gaye, Peter W. Gething, Raquel González, Francesco Grandesso, Philippe J. Guerin, Jean Paul Guthmann, Sally Hamour, Armedy Ronny Hasugian, Simon I. Hay, Georgina S. Humphreys, Vincent Jullien, Elizabeth Juma, Moses R. Kamya, Corine Karema, Jean R. Kiechel, Peter G. Kremsner, Sanjeev Krishna, Valérie Lameyre, Laminou M. Ibrahim, Sue J. Lee, Bertrand Lell, Andreas Martensson, Achille Massougbodji, Hervé Menan, Didier Ménard, Clara Menéndez, Martin Meremikwu, Clarissa Moreira, Carolyn Nabasumba, Michael Nambozi, Jean Louis Ndiaye, Frederic Nikiema, Christian Nsanzabana, Francine Ntoumi, Bernhards R. Ogutu, Piero Olliaro, Lyda Osorio, Jean Bosco Ouédraogo, Louis K. Penali, Mbaye Pene
Published 2018