A retrospective analysis of the haemodynamic and metabolic effects of fluid resuscitation in vietnamese adults with severe falciparum malaria

by Hoan Phu Nguyen, Josh Hanson, Delia Bethell, Thi Hoang Nguyen, Thi Hong Tran, Van Chuong Ly, Phu Loc Pham, Dinh Xuan Sinh, Arjen Dondorp, Nicholas White, Tran Tinh Hien, Nicholas Day
Published 2018

Fatal Plasmodium falciparum malaria causes specific patterns of splenic architectural disorganization

by Britta C. Urban, Tran T. Hien, Nicholas P. Day, Nguyen H. Phu, Rachel Roberts, Emsri Pongponratn, Margret Jones, Nguyen T.H. Mai, Delia Bethell, Gareth D.H. Turner, David Ferguson, Nicholas J. White, David J. Roberts
Published 2018

Ex vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia compared to Thailand

by Suwanna Chaorattanakawee, Chanthap Lon, Krisada Jongsakul, Jariyanart Gawee, Somethy Sok, Siratchana Sundrakes, Nareth Kong, Chatchadaporn Thamnurak, Soklyda Chann, Sorayut Chattrakarn, Chantida Praditpol, Nillawan Buathong, Nichapat Uthaimongkol, Philip Smith, Narongrid Sirisopana, Rekol Huy, Satharath Prom, Mark M. Fukuda, Delia Bethell, Douglas S. Walsh, Charlotte Lanteri, David Saunders
Published 2018

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

by Jennifer A. Flegg, Philippe J. Guérin, Francois Nosten, Elizabeth A. Ashley, Aung Pyae Phyo, Arjen M. Dondorp, Rick M. Fairhurst, Duong Socheat, Steffen Borrmann, Anders Björkman, Andreas Mårtensson, Mayfong Mayxay, Paul N. Newton, Delia Bethell, Youry Se, Harald Noedl, Mahamadou Diakite, Abdoulaye A. Djimde, Tran T. Hien, Nicholas J. White, Kasia Stepniewska
Published 2018

Evaluation of In Vitro Cross-Reactivity to Avian H5N1 and Pandemic H1N1 2009 Influenza Following Prime Boost Regimens of Seasonal Influenza Vaccination in Healthy Human Subjects: A...

by Delia Bethell, David Saunders, Anan Jongkaewwattana, Jarin Kramyu, Arunee Thitithayanont, Suwimon Wiboon-ut, Kosol Yongvanitchit, Amporn Limsalakpetch, Utaiwan Kum-Arb, Nichapat Uthaimongkol, Jean Michel Garcia, Ans E. Timmermans, Malik Peiris, Stephen Thomas, Anneke Engering, Richard G. Jarman, Duangrat Mongkolsirichaikul, Carl Mason, Nuanpan Khemnu, Stuart D. Tyner, Mark M. Fukuda, Douglas S. Walsh, Sathit Pichyangkul
Published 2018

Efficacy of two versus three-day regimens of dihydroartemisinin-piperaquine for uncomplicated malaria in military personnel in Northern Cambodia: An open-label randomized trial

by Chanthap Lon, Jessica E. Manning, Pattaraporn Vanachayangkul, Mary So, Darapiseth Sea, Youry Se, Panita Gosi, Charlotte Lanteri, Suwanna Chaorattanakawee, Sabaithip Sriwichai, Soklyda Chann, Worachet Kuntawunginn, Nillawan Buathong, Samon Nou, Douglas S. Walsh, Stuart D. Tyner, Jonathan J. Juliano, Jessica Lin, Michele Spring, Delia Bethell, Jaranit Kaewkungwal, Douglas Tang, Char Meng Chuor, Prom Satharath, David Saunders
Published 2018

Genetic loci associated with delayed clearance of plasmodium falciparum following artemisinin

by Shannon Takala-Harrison, Taane G. Clark, Christopher G. Jacob, Michael P. Cummings, Olivo Miotto, Arjen M. Dondorpe, Mark M. Fukuda, Francois Nosten, Harald Noedl, Mallika Imwong, Delia Bethell, Youry Se, Chanthap Lon, Stuart D. Tyner, David L. Saunders, Duong Socheat, Frederic Ariey, Aung Pyae Phyo, Peter Starzengruber, Hans Peter Fuehrer, Paul Swoboda, Kasia Stepniewska, Jennifer Flegg, Cesar Arze, Gustavo C. Cerqueira, Joana C. Silva, Stacy M. Ricklefs, Stephen F. Porcella, Robert M. Stephens, Matthew Adams, Leo J. Kenefic, Susana Campino, Sarah Auburn, Bronwyn MacInnis, Dominic P. Kwiatkowskid, Xin Zhuan Su, Nicholas J. White, Pascal Ringwald, Christopher V. Plowe
Published 2018

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): An open-label, randomised trial

by Arjen M. Dondorp, Caterina I. Fanello, Ilse Ce Hendriksen, Ermelinda Gomes, Amir Seni, Kajal D. Chhaganlal, Kalifa Bojang, Rasaq Olaosebikan, Nkechinyere Anunobi, Kathryn Maitland, Esther Kivaya, Tsiri Agbenyega, Samuel Blay Nguah, Jennifer Evans, Samwel Gesase, Catherine Kahabuka, George Mtove, Behzad Nadjm, Jacqueline Deen, Juliet Mwanga-Amumpaire, Margaret Nansumba, Corine Karema, Noella Umulisa, Aline Uwimana, Olugbenga A. Mokuolu, Olanrewaju T. Adedoyin, Wahab Br Johnson, Antoinette K. Tshefu, Marie A. Onyamboko, Tharisara Sakulthaew, Wirichada Pan Ngum, Kamolrat Silamut, Kasia Stepniewska, Charles J. Woodrow, Delia Bethell, Bridget Wills, Martina Oneko, Tim E. Peto, Lorenz Von Seidlein, Nicholas Pj Day, Nicholas J. White
Published 2018

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: An individual patient data meta-analysis

by Salim Abdulla, Elizabeth A. Ashley, Quique Bassat, Delia Bethell, Anders Björkman, Steffen Borrmann, Umberto D’Alessandro, Prabin Dahal, Nicholas P. Day, Mahamadou Diakite, Abdoulaye A. Djimde, Arjen M. Dondorp, Socheat Duong, Michael D. Edstein, Rick M. Fairhurst, M. Abul Faiz, Catherine Falade, Jennifer A. Flegg, Carole Fogg, Raquel Gonzalez, Brian Greenwood, Philippe J. Guérin, Jean Paul Guthmann, Kamal Hamed, Tran Tinh Hien, Ye Htut, Elizabeth Juma, Pharath Lim, Andreas Mårtensson, Mayfong Mayxay, Olugbenga A. Mokuolu, Clarissa Moreira, Paul Newton, Harald Noedl, Francois Nosten, Bernhards R. Ogutu, Marie A. Onyamboko, Seth Owusu-Agyei, Aung Pyae Phyo, Zul Premji, Ric N. Price, Sasithon Pukrittayakamee, Michael Ramharter, Issaka Sagara, Youry Se, Seila Suon, Kasia Stepniewska, Stephen A. Ward, Nicholas J. White, Peter A. Winstanley
Published 2018

Genetic architecture of artemisinin-resistant Plasmodium falciparum

by Olivo Miotto, Roberto Amato, Elizabeth A. Ashley, Bronwyn Macinnis, Jacob Almagro-Garcia, Chanaki Amaratunga, Pharath Lim, Daniel Mead, Samuel O. Oyola, Mehul Dhorda, Mallika Imwong, Charles Woodrow, Magnus Manske, Jim Stalker, Eleanor Drury, Susana Campino, Lucas Amenga-Etego, Thuy Nhien Nguyen Thanh, Hien Tinh Tran, Pascal Ringwald, Delia Bethell, Francois Nosten, Aung Pyae Phyo, Sasithon Pukrittayakamee, Kesinee Chotivanich, Char Meng Chuor, Chea Nguon, Seila Suon, Sokunthea Sreng, Paul N. Newton, Mayfong Mayxay, Maniphone Khanthavong, Bouasy Hongvanthong, Ye Htut, Kay Thwe Han, Myat Phone Kyaw, Md Abul Faiz, Caterina I. Fanello, Marie Onyamboko, Olugbenga A. Mokuolu, Christopher G. Jacob, Shannon Takala-Harrison, Christopher V. Plowe, Nicholas P. Day, Arjen M. Dondorp, Chris C.A. Spencer, Gilean Mcvean, Rick M. Fairhurst, Nicholas J. White, Dominic P. Kwiatkowski
Published 2018

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

by Olivo Miotto, Jacob Almagro-Garcia, Magnus Manske, Bronwyn MacInnis, Susana Campino, Kirk A. Rockett, Chanaki Amaratunga, Pharath Lim, Seila Suon, Sokunthea Sreng, Jennifer M. Anderson, Socheat Duong, Chea Nguon, Char Meng Chuor, David Saunders, Youry Se, Chantap Lon, Mark M. Fukuda, Lucas Amenga-Etego, Abraham V.O. Hodgson, Victor Asoala, Mallika Imwong, Shannon Takala-Harrison, François Nosten, Xin Zhuan Su, Pascal Ringwald, Frédéric Ariey, Christiane Dolecek, Tran Tinh Hien, Maciej F. Boni, Cao Quang Thai, Alfred Amambua-Ngwa, David J. Conway, Abdoulaye A. Djimdé, Ogobara K. Doumbo, Issaka Zongo, Jean Bosco Ouedraogo, Daniel Alcock, Eleanor Drury, Sarah Auburn, Oliver Koch, Mandy Sanders, Christina Hubbart, Gareth Maslen, Valentin Ruano-Rubio, Dushyanth Jyothi, Alistair Miles, John O'Brien, Chris Gamble, Samuel O. Oyola, Julian C. Rayner, Chris I. Newbold, Matthew Berriman, Chris C.A. Spencer, Gilean McVean, Nicholas P. Day, Nicholas J. White, Delia Bethell, Arjen M. Dondorp, Christopher V. Plowe, Rick M. Fairhurst, Dominic P. Kwiatkowski
Published 2018