Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Abstract. Background: The emergence of Plasmodium falciparum resistance to artemisinins in Southeast Asia threatens the control of malaria worldwide. The pharmacodynamic hallmark of artemisinin derivatives is rapid parasite clearance (a short parasite half-life), therefore, the in vivo phenotype of...

Full description

Saved in:
Bibliographic Details
Main Authors: Jennifer A. Flegg, Philippe J. Guérin, Francois Nosten, Elizabeth A. Ashley, Aung Pyae Phyo, Arjen M. Dondorp, Rick M. Fairhurst, Duong Socheat, Steffen Borrmann, Anders Björkman, Andreas Mårtensson, Mayfong Mayxay, Paul N. Newton, Delia Bethell, Youry Se, Harald Noedl, Mahamadou Diakite, Abdoulaye A. Djimde, Tran T. Hien, Nicholas J. White, Kasia Stepniewska
Other Authors: University of Oxford
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31839
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University

Internet

https://repository.li.mahidol.ac.th/handle/123456789/31839

Similar Items