Ex-vivo cytoadherence phenotypes of Plasmodium falciparum strains from Malian children with hemoglobins A,S, and C.

Sickle hemoglobin (Hb) S and HbC may protect against malaria by reducing the expression of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) on the surface of parasitized red blood cells (RBCs), thereby weakening their cytoadherence to microvascular endothelial cells (MVECs) and impai...

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Bibliographic Details
Main Authors: Beaudry, Jeanette T., Krause, Michael A., Diakite, Seidina A. S., Fay, Michael P., Joshi, Gyan, Diakite, Mahamadou, White, Nicholas J., Fairhurst, Rick M.
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/824
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Institution: Mahidol University
Language: English