Ex-vivo cytoadherence phenotypes of Plasmodium falciparum strains from Malian children with hemoglobins A,S, and C.
Sickle hemoglobin (Hb) S and HbC may protect against malaria by reducing the expression of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) on the surface of parasitized red blood cells (RBCs), thereby weakening their cytoadherence to microvascular endothelial cells (MVECs) and impai...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/824 |
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Institution: | Mahidol University |
Language: | English |