Ex-vivo cytoadherence phenotypes of Plasmodium falciparum strains from Malian children with hemoglobins A,S, and C.
Sickle hemoglobin (Hb) S and HbC may protect against malaria by reducing the expression of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) on the surface of parasitized red blood cells (RBCs), thereby weakening their cytoadherence to microvascular endothelial cells (MVECs) and impai...
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Main Authors: | Beaudry, Jeanette T., Krause, Michael A., Diakite, Seidina A. S., Fay, Michael P., Joshi, Gyan, Diakite, Mahamadou, White, Nicholas J., Fairhurst, Rick M. |
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Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/824 |
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Institution: | Mahidol University |
Language: | English |
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