Genetic loci associated with delayed clearance of plasmodium falciparum following artemisinin

• Main Authors: Shannon Takala-Harrison, Taane G. Clark, Christopher G. Jacob, Michael P. Cummings, Olivo Miotto, Arjen M. Dondorpe, Mark M. Fukuda, Francois Nosten, Harald Noedl, Mallika Imwong, Delia Bethell, Youry Se, Chanthap Lon, Stuart D. Tyner, David L. Saunders, Duong Socheat, Frederic Ariey, Aung Pyae Phyo, Peter Starzengruber, Hans Peter Fuehrer, Paul Swoboda, Kasia Stepniewska, Jennifer Flegg, Cesar Arze, Gustavo C. Cerqueira, Joana C. Silva, Stacy M. Ricklefs, Stephen F. Porcella, Robert M. Stephens, Matthew Adams, Leo J. Kenefic, Susana Campino, Sarah Auburn, Bronwyn MacInnis, Dominic P. Kwiatkowskid, Xin Zhuan Su, Nicholas J. White, Pascal Ringwald, Christopher V. Plowe
• Other Authors: University of Maryland School of Medicine
• Format: Article
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/32834
• Institution: Mahidol University

The recent emergence of artemisinin-resistant Plasmodium falciparum malaria in western Cambodia could threaten prospects for malaria elimination. Identification of the genetic basis of resistance would provide tools for molecular surveillance, aiding efforts to contain resistance. Clinical trials of...