Declining responsiveness of plasmodium falciparum infections to Artemisinin-Based combination treatments on the Kenyan coast

• Main Authors: Steffen Borrmann, Philip Sasi, Leah Mwai, Mahfudh Bashraheil, Ahmed Abdallah, Steven Muriithi, Henrike Frühauf, Barbara Schaub, Johannes Pfeil, Judy Peshu, Warunee Hanpithakpong, Anja Rippert, Elizabeth Juma, Benjamin Tsofa, Moses Mosobo, Brett Lowe, Faith Osier, Greg Fegan, Niklas Lindegårdh, Alexis Nzila, Norbert Peshu, Margaret Mackinnon, Kevin Marsh
• Other Authors: Kenya Medical Research Institute
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11239
• Institution: Mahidol University

Background: The emergence of artemisinin-resistant P. falciparum malaria in South-East Asia highlights the need for continued global surveillance of the efficacy of artemisinin-based combination therapies. Methods: On the Kenyan coast we studied the treatment responses in 474 children 6-59 months ol...