Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast.

• Main Authors: Borrmann, Steffen, Sasi, Philip, Mwai, Leah, Bashraheil, Mahfudh, Abdallah, Ahmed, Muriith, Steven, Frühauf, Henrike, Schaub, Barbara, Pfeil, Johannes, Peshu, Judy, Warunee Hanpithakpong, วารุณี หาญพิทักษ์พงศ์, Rippert, Anja, Juma, Elizabeth, Tsofa, Benjamin, Mosobo, Moses, Lowe, Brett, Osier, Faith, Fegan, Greg, Lindegårdh, Niklas, Nzila, Alexis, Peshu, Norbert, Mackinnon, Margaret, Marsh, Kevin
• Format: Article
• Language: English
• Published: 2015
• Subjects: Antimalarials; Child, Preschool; Drug combinations; Fluorenes; Kenya; Malaria, Falciparum/drug therapy; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/799
• Institution: Mahidol University

BACKGROUND: The emergence of artemisinin-resistant P. falciparum malaria in South-East Asia highlights the need for continued global surveillance of the efficacy of artemisinin-based combination therapies. METHODS: On the Kenyan coast we studied the treatment responses in 474 children 6-59 months ol...