Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: implications for prevention, treatment and elimination strategies

• Main Authors: Rupam Tripura, Peto, Thomas J., Jeremy Chalk, Lee, Sue J., Pasathorn Sirithiranont, Chea Nguon, Mehul Dhorda, Seidlein, Lorenz von, Maude, Richard J., Day, Nicholas P. J., Mallika Imwong, White, Nicholas J., Dondorp, Arjen M.
• Other Authors: Mahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research Unit
• Format: Article
• Language: English
• Published: 2017
• Subjects: Open Access article; Malaria; Persistence; Cohort; Plasmodium; Falciparum; Vivax; Clearance; Artemisinins; Resistance; Pailin; Cambodia; PCR
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/3149
• Institution: Mahidol University

Background: Subclinical Plasmodium parasitaemia is an important reservoir for the transmission and persistence of malaria, particularly in low transmission areas. Methods: Using ultrasensitive quantitative PCR (uPCR) for the detection of parasitaemia, the entire population of three Cambodian vill...