Laboratory Detection of Artemisinin-Resistant Plasmodium falciparum.

• Main Authors: Kesinee Chotivanich, เกศินี โชติวานิช, Tripura, Rupam, Das, Debashish, Poravuth Yi,c, Day, Nicholas P. J., Sasithon Pukrittayakamee, ศศิธร ผู้กฤตยาคามี, Chuor, Char Meng, Socheat, Duong, Dondorp, Arjen M., White, Nicholas J.
• Format: Article
• Language: English
• Published: 2014
• Subjects: Artemisinin-Resistant; Plasmodium falciparum; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/743
• Institution: Mahidol University

Conventional 48-h in vitro susceptibility tests have low sensitivity in identifying artemisinin-resistant Plasmodium falciparum, defined phenotypically by low in vivo parasite clearance rates. We hypothesized originally that this discrepancy was explained by a loss of ring-stage susceptibility and s...