Plasmodium falciparum rosetting protects schizonts against artemisinin

• Main Authors: Lee, Wenn-Chyau, Russell, Bruce, Lee, Bernett, Chu, Cindy S., Phyo, Aung Pyae, Sriprawat, Kanlaya, Lau, Yee-Ling, Nosten, François, Rénia, Laurent
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Medicine; Science::Biological sciences; Artemisinin Resistance; Plasmodium Falciparum
• 在線閱讀: https://hdl.handle.net/10356/154208
• 機構: Nanyang Technological University

Background: Artemisinin (ART) resistance in Plasmodium falciparum is thought to occur during the early stage of the parasite's erythrocytic cycle. Here, we identify a novel factor associated with the late stage parasite development that contributes to ART resistance. Methods: Rosetting rates o...