Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

by Frances Rocamora, Lei Zhu, Kek Yee Liong, Arjen Dondorp, Olivo Miotto, Sachel Mok, Zbynek Bozdech
Published 2019

Reverse transcription PCR to detect low density malaria infections

by Peter Christensen, Zbynek Bozdech, Wanitda Watthanaworawit, Mallika Imwong, Laurent Rénia, Benoît Malleret, Clare Ling, François Nosten
Published 2022

A comprehensive RNA handling and transcriptomics guide for high-throughput processing of Plasmodium blood-stage samples

by Michal Kucharski, Jaishree Tripathi, Sourav Nayak, Lei Zhu, Grennady Wirjanata, Rob W. Van Der Pluijm, Mehul Dhorda, Arjen Dondorp, Zbynek Bozdech
Published 2020

The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites

by Zbynek Bozdech, Sachel Mok, Guangan Hu, Mallika Imwong, Anchalee Jaidee, Bruce Russell, Hagai Ginsburg, Francois Nosten, Nicholas P J Day, Nicholas J. White, Jane M. Carlton, Peter R. Preiser
Published 2018

Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

by Con Dogovski, Stanley C. Xie, Gaetan Burgio, Jess Bridgford, Sachel Mok, James M. McCaw, Kesinee Chotivanich, Shannon Kenny, Nina Gnädig, Judith Straimer, Zbynek Bozdech, David A. Fidock, Julie A. Simpson, Arjen M. Dondorp, Simon Foote, Nectarios Klonis, Leann Tilley
Published 2018

Comparative Heterochromatin Profiling Reveals Conserved and Unique Epigenome Signatures Linked to Adaptation and Development of Malaria Parasites

by Sabine A. Fraschka, Michael Filarsky, Regina Hoo, Igor Niederwieser, Xue Yan Yam, Nicolas M.B. Brancucci, Franziska Mohring, Annals T. Mushunje, Ximei Huang, Peter R. Christensen, Francois Nosten, Zbynek Bozdech, Bruce Russell, Robert W. Moon, Matthias Marti, Peter R. Preiser, Richárd Bártfai, Till S. Voss
Published 2019

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

by Sachel Mok, Mallika Imwong, Margaret J. Mackinnon, Joan Sim, Ramya Ramadoss, Poravuth Yi, Mayfong Mayxay, Kesinee Chotivanich, Kek Yee Liong, Bruce Russell, Duong Socheat, Paul N. Newton, Nicholas P.J. Day, Nicholas J. White, Peter R. Preiser, François Nosten, Arjen M. Dondorp, Zbynek Bozdech
Published 2018

Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors

by Aung Pyae Phyo, Elizabeth A. Ashley, Tim J.C. Anderson, Zbynek Bozdech, Verena I. Carrara, Kanlaya Sriprawat, Shalini Nair, Marina Mc Dew White, Jerzy Dziekan, Clare Ling, Stephane Proux, Kamonchanok Konghahong, Atthanee Jeeyapant, Charles J. Woodrow, Mallika Imwong, Rose McGready, Khin Maung Lwin, Nicholas P.J. Day, Nicholas J. White, Francois Nosten
Published 2018

The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background

by Lei Zhu, Jaishree Tripathi, Frances Maureen Rocamora, Olivo Miotto, Rob van der Pluijm, Till S. Voss, Sachel Mok, Dominic P. Kwiatkowski, François Nosten, Nicholas P.J. Day, Nicholas J. White, Arjen M. Dondorp, Zbynek Bozdech, Aung Pyae Phyo, Elizabeth A. Ashley, Frank Smithuis, Khin Lin, Kyaw Myo Tun, M. Abul Faiz, Mayfong Mayxay, Mehul Dhorda, Nguyen Thanh Thuy-Nhien, Paul N. Newton, Sasithon Pukrittayakamee, Tin M. Hlaing, Tran Tinh Hien, Ye Htut
Published 2019

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

by Lei Zhu, Rob W. van der Pluijm, Michal Kucharski, Sourav Nayak, Jaishree Tripathi, Nicholas J. White, Nicholas P.J. Day, Abul Faiz, Aung Pyae Phyo, Chanaki Amaratunga, Dysoley Lek, Elizabeth A. Ashley, François Nosten, Frank Smithuis, Hagai Ginsburg, Lorenz von Seidlein, Khin Lin, Mallika Imwong, Kesinee Chotivanich, Mayfong Mayxay, Mehul Dhorda, Hoang Chau Nguyen, Thuy Nhien Thanh Nguyen, Olivo Miotto, Paul N. Newton, Podjanee Jittamala, Rupam Tripura, Sasithon Pukrittayakamee, Thomas J. Peto, Tran Tinh Hien, Arjen M. Dondorp, Zbynek Bozdech
Published 2022

Screening and characterization of antimalarial resistance related genetic structural variations in P. falciparum

by Assisi, Christina
Published 2022

Characterizing the role of Cyp19B as a contributing factor to artemisinin resistance in Plasmodium falciparum

by Toh, Victoria Le Yi
Published 2022

Regulation of gene expression during DNA damage response in Plasmodium falciparum

by Gupta, Devendra Kumar
Published 2016

Drug target discovery in human malaria; inhibition of histone deacetylases (HDAC) in Plasmodium falciparum.

by Chua, Rui Jing.
Published 2012

Characterisation of the mediator complex in the malarial parasite Plasmodium falciparum

by Uthra Balasubramaniyan Iyer
Published 2018

"Transcriptional regulation and transcription factors as novel drugs targets for human malaria".

by Sakinah Mulyana.
Published 2012

Cellular characterization of artemisinin resistance in human malaria.

by Low, Kum Yong.
Published 2013

Transcriptional variation in human malaria parasites and its association with drug resistance

by Mok, Sachel
Published 2013

System biology approach for functional annotation of the genome of human malaria parasite plasmodium falciparum and antimalarial drug discovery

by Naw, Wah Wah
Published 2015

Exploration of the traditional Chinese medicine extracts as antimalaria drugs.

by Kua, Baohe.
Published 2013