Transcriptional variation in human malaria parasites and its association with drug resistance

by Mok, Sachel
Published 2013

Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

by Rocamora, Frances, Zhu, Lei, Liong, Kek Yee, Dondorp, Arjen, Miotto, Olivo, Mok, Sachel, Bozdech, Zbynek
Published 2018

Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa

by Simam, Joan, Rono, Martin, Ngoi, Joyce, Nyonda, Mary, Mok, Sachel, Marsh, Kevin, Bozdech, Zbynek, Mackinnon, Margaret
Published 2018

Plasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures

by Lapp, Stacey A, Mok, Sachel, Zhu, Lei, Wu, Hao, Preiser, Peter R, Bozdech, Zbynek, Galinski, Mary R
Published 2015

Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum

by Chin, Wai Hoe, Zhu, Lei, Mok, Sachel, Luah, Yen-Hoon, Lim, Eng-How, Bozdech, Zbynek, Gupta, Archna P.
Published 2013

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

by Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois, Tan, Kevin Shyong-Wei
Published 2013

New insights into the plasmodium vivax transcriptome using RNA-Seq

by Zhu, Lei, Mok, Sachel, Imwong, Mallika, Jaidee, Anchalee, Russell, Bruce, Nosten, Francois, Day, Nicholas P., White, Nicholas J., Bozdech, Zbynek, Preiser, Peter Rainer
Published 2018

Transcriptional variation in the malaria parasite Plasmodium falciparum

by Gupta, Archna P., Crowley, Valerie M., Rovira-Graells, Núria, Planet, Evarist, Mok, Sachel, Pouplana, Llús Ribas de, Preiser, Peter Rainer, Bozdech, Zbynek, Cortés, Alfred
Published 2013

Integrated analysis of the Plasmodium species transcriptome

by Hoo, Regina, Zhu, Lei, Amaladoss, Anburaj, Mok, Sachel, Natalang, Onguma, Lapp, Stacey A., Hu, Guangan, Liew, Kingsley, Galinski, Mary R., Bozdech, Zbynek, Preiser, Peter Rainer
Published 2018

Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmo...

by Kucharski, Michal, Wirjanata, Grennady, Nayak, Sourav, Boentoro, Josephine, Dziekan, Jerzy Michal, Assisi, Christina, van der Pluijm, Rob W., Miotto, Olivo, Mok, Sachel, Dondorp, Arjen M., Bozdech, Zbynek
Published 2023

The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background

by Zhu, Lei, Tripathi, Jaishree, Rocamora, Frances Maureen, Miotto, Olivo, van der Pluijm, Rob, Voss, Till S., Mok, Sachel, Kwiatkowski, Dominic P., Nosten, François, Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M., Bozdech, Zbynek
Published 2019

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

by Claessens, Antoine, Adams, Yvonne, Ghumra, Ashfaq, Lindergard, Gabriella, Andisi, Cheryl, Mok, Sachel, Turner, Louise, Arman, Mònica, Raza, Ahmed, Bozdech, Zbynek, Rowe, J. Alexandra, Buchan, Caitlin C., Bull, Peter C., Gupta, Archna P., Wang, Christian W.
Published 2013

Adaptation of Plasmodium falciparum to its transmission environment

by Rono, Martin K., Nyonda, Mary A., Simam, Joan J., Ngoi, Joyce M., Mok, Sachel, Kortok, Moses M., Abdullah, Abdullah S., Elfaki, Mohammed M., Waitumbi, John N., El-Hassan, Ibrahim M., Marsh, Kevin, Bozdech, Zbynek, Mackinnon, Margaret J.
Published 2020

Targeting the cell stress response of plasmodium falciparum to overcome artemisinin resistance

by Dogovski, Con, Xie, Stanley C., Burgio, Gaetan, Bridgford, Jess, Mok, Sachel, McCaw, James M., Chotivanich, Kesinee, Kenny, Shannon, Gnädig, Nina, Straimer, Judith, Bozdech, Zbynek, Fidock, David A., Simpson, Julie A., Dondorp, Arjen M., Foote, Simon, Klonis, Nectarios, Tilley, Leann
Published 2015

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

by Mok, Sachel, Mallika Imwong, มัลลิกา อิ่มวงศ์, Mackinnon, Margaret J., Sim, Joan, Ramadoss, Ramya, Yi, Poravuth, Mayfong Mayxay, Kesinee Chotivanich, เกศินี โชติวานิช, Liong, Kek-Yee, Russell, Bruce, Socheat, Duong, Newton, Paul N., Day, Nicholas P.J., White, Nicholas J., Preiser, Peter R., Nosten, François, Dondorp, Arjen M., Bozdech, Zbynek
Published 2013

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

by Mok, Sachel, Yeo, Tomas, Hong, Davin, Shears, Melanie J., Ross, Leila S., Ward, Kurt E., Dhingra, Satish K., Kanai, Mariko, Bridgford, Jessica L., Tripathi, Abhai K., Mlambo, Godfree, Burkhard, Anna Y., Ansbro, Megan R., Fairhurst, Kate J., Gil-Iturbe, Eva, Park, Heekuk, Rozenberg, Felix D., Kim, Jonathan, Mancia, Filippo, Fairhurst, Rick M., Quick, Matthias, Uhlemann, Anne-Catrin, Sinnis, Photini, Fidock, David A.
Published 2024