Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

• المؤلفون الرئيسيون: Rocamora, Frances, Zhu, Lei, Liong, Kek Yee, Dondorp, Arjen, Miotto, Olivo, Mok, Sachel, Bozdech, Zbynek
• مؤلفون آخرون: Cooper, Roland
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Artemisinin Resistance; Parasites
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/89168; http://hdl.handle.net/10220/44831
• المؤسسة: Nanyang Technological University

Due to their remarkable parasitocidal activity, artemisinins represent the key components of first-line therapies against Plasmodium falciparum malaria. However, the decline in efficacy of artemisinin-based drugs jeopardizes global efforts to control and ultimately eradicate the disease. To better u...