Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

Due to their remarkable parasitocidal activity, artemisinins represent the key components of first-line therapies against Plasmodium falciparum malaria. However, the decline in efficacy of artemisinin-based drugs jeopardizes global efforts to control and ultimately eradicate the disease. To better u...

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Bibliographic Details
Main Authors: Rocamora, Frances, Zhu, Lei, Liong, Kek Yee, Dondorp, Arjen, Miotto, Olivo, Mok, Sachel, Bozdech, Zbynek
Other Authors: Cooper, Roland
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/89168
http://hdl.handle.net/10220/44831
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Institution: Nanyang Technological University
Language: English