Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

• Main Authors: Sachel Mok, Mallika Imwong, Margaret J. Mackinnon, Joan Sim, Ramya Ramadoss, Poravuth Yi, Mayfong Mayxay, Kesinee Chotivanich, Kek Yee Liong, Bruce Russell, Duong Socheat, Paul N. Newton, Nicholas P.J. Day, Nicholas J. White, Peter R. Preiser, François Nosten, Arjen M. Dondorp, Zbynek Bozdech
• Other Authors: Nanyang Technological University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11492
• Institution: Mahidol University

Background: Artemisinin resistance in Plasmodium falciparum malaria has emerged in Western Cambodia. This is a major threat to global plans to control and eliminate malaria as the artemisinins are a key component of antimalarial treatment throughout the world. To identify key features associated wit...