Caspase proteases mediate apoptosis induced by anticancer agent preactivated MC540 in human tumor cell lines

by Pervaiz, S., Hirpara, J.L., Clement, M.-V.
Published 2011

Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria

by Clement, M.-V., Hirpara, J.L., Pervaiz, S.
Published 2011

LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization

by Poh, T.W., Huang, S., Hirpara, J.L., Pervaiz, S.
Published 2011

Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells

by Clement, M.-V., Hirpara, J.L., Chawdhury, S.-H., Pervaiz, S.
Published 2011

Superoxide anion inhibits drug-induced tumor cell death

by Pervaiz, S., Hirpara, J.L., Ramalingam, J.K., Clement, M.-V.
Published 2011

Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas

by Hirpara, J.L, Loh, T, Ng, S.B, Chng, W.J, Pervaiz, S
Published 2020

Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-Myc

by Raman, D., Chong, Stephen J. F., Iskandar, K., Hirpara, J.L., Pervaiz, S.
Published 2021

FLIP: A flop for execution signals

by Subramaniam, K., Hirpara, J.L., Tucker-Kellogg, L., Tucker-Kellogg, G., Pervaiz, S.
Published 2014

Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatinresistant cancer cells

by Seah, S, Low, I, Hirpara, J.L, Sachaphibulkij, K, Kroemer, G, Brenner, C, Pervaiz, S
Published 2020

Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase 8-dependent apoptosis in human leukemia and melanoma cells

by Pervaiz, S., Seyed, M.A., Hirpara, J.L., Clement, M.-V., Loh, K.W.
Published 2011

Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of bax during drug-induced apoptosis of tumor cells

by Ahmad, K.A., Iskandar, K.B., Hirpara, J.L., Pervaiz, S., Clement, M.-V.
Published 2011

Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation

by Wong, C.H., Iskandar, K.B., Yadav, S.K., Hirpara, J.L., Loh, T., Pervaiz, S.
Published 2014

Do STAT3 inhibitors have potential in the future for cancer therapy?

by Andrea Wong, Gautam Sethi, Boon-Cher Goh, Hirpara J.L., Pervaiz S., Eu J.Q.
Published 2018

Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells

by Hirpara, J.L., Seyed, M.A., Loh, K.W., Dong, H., Kini, R.M., Pervaiz, S.
Published 2016

Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors

by Lee M., Hirpara J.L., Eu J.-Q., Sethi G., Wang L., Goh B.-C., Wong A.L.
Published 2020

Cleavage of misfolded nuclear receptor corepressor confers resistance to unfolded protein response-induced apoptosis

by Ng, A.P.P., Fong, J.H., Nin, D.S., Chen, C.-S., Pervaiz, S., Khan, M., Hirpara, J.L., Asou, N.
Published 2011

The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity

by Velaithan, R., Kang, J., Hirpara, J.L., Loh, T., Goh, B.C., Le Bras, M., Brenner, C., Clement, M.-V., Pervaiz, S.
Published 2014

Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide

by Kang, J, Fei Chong, S.J, Qi Ooi, V.Z, Vali, S, Kumar, A, Kapoor, S, Abbasi, T, Hirpara, J.L, Loh, T, Goh, B.C, Pervaiz, S
Published 2020