Kill502, a novel multitargeted receptor tyrosine kinase inhibitor, induces growth arrest and apoptosis of human leukemia cells in vitro and in vivo

by Nishioka, C, Ikezoe, T, Yang, J, Miwa, A, Tasaka, T, Kuwayama, Y, Togitani, K, Koeffler, H.P, Yokoyama, A
Published 2020

Expression of p-JAK2 predicts clinical outcome and is a potential molecular target of acute myelogenous leukemia

by Ikezoe, T., Kojima, S., Furihata, M., Yang, J., Nishioka, C., Takeuchi, A., Isaka, M., Koeffler, H.P., Yokoyama, A.
Published 2016

Clinical significance of aberrant DNA methylation in childhood acute lymphoblastic leukemia

by Takeuchi, S., Matsushita, M., Zimmermann, M., Ikezoe, T., Komatsu, N., Seriu, T., Schrappe, M., Bartram, C.R., Koeffler, H.P.
Published 2016

Inhibition of IRE1?-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

by Sun, H, Lin, D.-C, Guo, X, Masouleh, B.K, Gery, S, Cao, Q, Alkan, S, Ikezoe, T, Akiba, C, Paquette, R, Chien, W, Müller-Tidow, C, Jing, Y, Agelopoulos, K, Müschen, M, Koeffler, H.P
Published 2020

Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia (vol 30, pg 1672, 2016)

by Madan, V, Shyamsunder, P, Han, L, Mayakonda, A, Nagata, Y, Sundaresan, J, Kanojia, D, Yoshida, K, Ganesan, S, Hattori, N, Fulton, N, Tan, KT, Alpermann, T, Kuo, MC, Rostami, S, Matthews, J, Sanada, M, Liu, L-Z, Shiraishi, Y, Miyano, S, Chendamarai, E, Hou, HA, Malnassy, G, Ma, T, Garg, M, Ding, LW, Sun, QY, Chien, W, Ikezoe, T, Lill, M, Biondi, A, Larson, RA, Powell, BL, Lubbert, M, Chng, WJ, Tien, HF, Heuser, M, Ganser, A, Koren-Michowitz, M, Kornblau, SM, Kantarjian, HM, Nowak, D, Hofmann, WK, Yang, H, Stock, W, Ghavamzadeh, A, Alimoghaddam, K, Haferlach, T, Ogawa, S, Shih, LY, Mathews, V, Koeffler, HP
Published 2023

Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia

by Madan, V, Shyamsunder, P, Han, L, Mayakonda, A, Nagata, Y, Sundaresan, J, Kanojia, D, Yoshida, K, Ganesan, S, Hattori, N, Fulton, N, Tan, KT, Alpermann, T, Kuo, MC, Rostami, S, Matthews, J, Sanada, M, Liu, L-Z, Shiraishi, Y, Miyano, S, Chendamarai, E, Hou, HA, Malnassy, G, Ma, T, Garg, M, Ding, LW, Sun, QY, Chien, W, Ikezoe, T, Lill, M, Biondi, A, Larson, RA, Powell, BL, Lubbert, M, Chng, WJ, Tien, HF, Heuser, M, Ganser, A, Koren-Michowitz, M, Kornblau, SM, Kantarjian, HM, Nowak, D, Hofmann, WK, Yang, H, Stock, W, Ghavamzadeh, A, Alimoghaddam, K, Haferlach, T, Ogawa, S, Shih, LY, Mathews, V, Koeffler, HP
Published 2022

Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia (vol 30, pg 1672, 2016)

by Madan, V, Shyamsunder, P, Han, L, Mayakonda, A, Nagata, Y, Sundaresan, J, Kanojia, D, Yoshida, K, Ganesan, S, Hattori, N, Fulton, N, Tan, KT, Alpermann, T, Kuo, MC, Rostami, S, Matthews, J, Sanada, M, Liu, L-Z, Shiraishi, Y, Miyano, S, Chendamarai, E, Hou, HA, Malnassy, G, Ma, T, Garg, M, Ding, LW, Sun, QY, Chien, W, Ikezoe, T, Lill, M, Biondi, A, Larson, RA, Powell, BL, Lubbert, M, Chng, WJ, Tien, HF, Heuser, M, Ganser, A, Koren-Michowitz, M, Kornblau, SM, Kantarjian, HM, Nowak, D, Hofmann, WK, Yang, H, Stock, W, Ghavamzadeh, A, Alimoghaddam, K, Haferlach, T, Ogawa, S, Shih, LY, Mathews, V, Koeffler, HP
Published 2022

Long-term safety and efficacy of ravulizumab in patients with paroxysmal nocturnal hemoglobinuria: 2-year results from two pivotal phase 3 studies

by Kulasekararaj, AG, Griffin, M, Langemeijer, S, Usuki, K, Kulagin, A, Ogawa, M, Yu, J, Mujeebuddin, A, Nishimura, JI, Lee, JW, Peffault de Latour, R, 301/302 Study Group, Latypova, A, Barcellini, W, Barraco, F, Beam, D, Bettelheim, P, Borisenkova, E, Brodsky, A, Carnley, B, Cermak, J, Chen, TY, Chew, LP, Chew, TK, Choi, CW, Choi, Y, Chung, JS, De Guibert, S, Devos, T, Dunaev, Y, Dwilewicz-Trojaczek, J, Edahiro, Y, Elykomov, I, Engelberger, MI, Pomponi, F, Fuereder, W, Fujii, N, Fujiwara, S, Galieni, P, Gaya Valls, A, Girault, S, Gomez Almaguer, D, Gonzalez Fernandez, FA, Gritsaev, S, Gunduz, E, Hantaweepant, C, Harada, H, Höglund, M, Huang, WH, Husin, A, Ikezoe, T, Ishiyama, K, Ito, Y, Jang, JH, Jo, DY, Kang, KW, Kennedy, J, Kim, HJ, Kim, JA, Kim, JS, Kimura, F, Kobune, M, Kosugi, H, Kulasekararaj, A, Lai, KM, Larratt, L, Lee, GW, Lee, JH, Lee, JH, Lee, JW, Lin, CC, Lukina, E, Martynova, E, Matsumura, I, Meike, G, Menosi Gualandro, SF, Minaeva, N, Mori, Y, Morita, K, Morselli Ramalho, FM, Mun, YC, Muus, P, Myasnikov, A, Naito, K, Ninomiya, H, Nogami, A, Notaro, R, Ojeda Gutierrez, E, Okada, M, Okamoto, S, Olkhovik, T, Pane, F, Paquette, R, Park, JS, Peffault de la Tour, R, Piatek, C, Piekarska, A, Pontes Reis, ML, Pospelova, T, Ptushkin, V, Roeth, A
Published 2023