Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice

by Lim, W.-W., Ng, B., Widjaja, A., Xie, C., Su, L., Ko, N., Lim, S.-Y., Kwek, X.-Y., Lim, S., Cook, S.A., Schafer, S.
Published 2021

Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo

by Zhou J, Ng B., Ko N.S.J., Fiedler L.R., Khin E., Lim A., Sahib N.E., Wu Y., Chothani S.P., Schafer S., Bay B.-H., Sinha R.A., Cook S.A., Yen P.M.
Published 2020

Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models

by Lim, W.-W., Corden, B., Ng, B., Vanezis, K., D’Agostino, G., Widjaja, A.A., Song, W.-H., Xie, C., Su, L., Kwek, X.-Y., Tee, N.G.Z., Dong, J., Ko, N.S.J., Wang, M., Pua, C.J., Jamal, M.H., Soh, B., Viswanathan, S., Schafer, S., Cook, S.A.
Published 2021

Wars2 is a determinant of angiogenesis

by Wang M., Sips P., Khin E., Rotival M., Sun X., Ahmed R., Widjaja A.A., Schafer S., Yusoff P., Choksi P.K., Ko N.S.J., Singh M.K., Epstein D., Guan Y., Houštěk J., Mracek T., Nuskova H., Mikell B., Tan J., Pesce F., Kolar F., Bottolo L., Mancini M., Hubner N., Pravenec M., Petretto E., Macrae C., Cook S.A.
Published 2019

Titin-truncating variants affect heart function in disease cohorts and the general population

by Schafer S., De Marvao A., Adami E., Fiedler L.R., Ng B., Khin E., Rackham O.J.L., Van Heesch S., Pua C.J., Kui M., Walsh R., Tayal U., Prasad S.K., Dawes T.J.W., Ko N.S.J., Sim D., Chan L.L.H., Chin C.W.L., Mazzarotto F., Barton P.J., Kreuchwig F., De Kleijn D.P.V., Totman T., Biffi C., Tee N., Rueckert D., Schneider V., Faber A., Regitz-Zagrosek V., Seidman J.G., Seidman C.E., Linke W.A., Kovalik J.-P., O'Regan D., Ware J.S., Hubner N., Cook S.A.
Published 2019

IL-11 is a crucial determinant of cardiovascular fibrosis

by Schafer S., Viswanathan S., Widjaja A.A., Lim W.-W., Moreno-Moral A., DeLaughter D.M., Ng B., Patone G., Chow K., Khin E., Tan J., Chothani S.P., Ye L., Rackham O.J.L., Ko N.S.J., Sahib N.E., Pua C.J., Zhen N.T.G., Xie C., Wang M., Maatz H., Lim S., Saar K., Blachut S., Petretto E., Schmidt S., Putoczki T., Guimarães-Camboa N., Wakimoto H., Van Heesch S., Sigmundsson K., Lim S.L., Soon J.L., Chao V.T.T., Chua Y.L., Tan T.E., Evans S.M., Loh Y.J., Jamal M.H., Ong K.K., Chua K.C., Ong B.-H., Chakaramakkil M.J., Seidman J.G., Seidman C.E., Hubner N., Sin K.Y.K., Cook S.A.
Published 2019