Reply: Normalization procedures and detection of linkage signal in genetical-genomics experiments [6]

by Petretto E., Mangion J., Cook S.A., Aitman T.J., Pravenec M., Schulz H., Fischer J., Hubner N.
Published 2018

Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat

by Mancini M., Petretto E., Kleinert C., Scavone A., De T., Cook S., Silhavy J., Zidek V., Pravenec M., D'Amati G., Camici P.G.
Published 2018

Genome-wide co-expression analysis in multiple tissues

by Grieve I.C., Dickens N.J., Pravenec M., Kren V., Hubner N., Cook S.A., Aitman T.J., Petretto E., Mangion J.
Published 2018

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans

by Langley S.R., Bottolo L., Kunes J., Zicha J., Zidek V., Hubner N., Cook S.A., Pravenec M., Aitman T.J., Petretto E.
Published 2018

New insights into the genetic control of gene expression using a bayesian multi-tissue approach

by Petretto E., Bottolo L., Langley S.R., Heinig M., McDermott-Roe C., Sarwar R., Pravenec M., Hübner N., Aitman T.J., Cook S.A., Richardson S.
Published 2018

Distribution and functional impact of DNA copy number variation in the rat

by Guryev V., Saar K., Adamovic T., Verheul M., Van Heesch S.A.A.C., Cook S., Pravenec M., Aitman T., Jacob H., Shull J.D., Hubner N., Cuppen E.
Published 2018

Heritability and tissue specificity of expression quantitative trait loci

by Petretto E., Mangion J., Dickens N.J., Cook S.A., Kumaran M.K., Lu H., Fischer J., Maatz H., Kren V., Pravenec M., Hubner N., Aitman T.J.
Published 2018

Translational regulation shapes the molecular landscape of complex disease phenotypes

by Schafer S., Adami E., Heinig M., Rodrigues K.E.C., Kreuchwig F., Silhavy J., Van Heesch S., Simaite D., Rajewsky N., Cuppen E., Pravenec M., Vingron M., Cook S.A., Hubner N.
Published 2016

Natural variation of histone modification and its impact on gene expression in the rat genome

by Rintisch C., Heinig M., Bauerfeind A., Schafer S., Mieth C., Patone G., Hummel O., Chen W., Cook S., Cuppen E., Colom‚-Tatch‚ M., Johannes F., Jansen R.C., Neil H., Werner M., Pravenec M., Vingron M., Hubner N.
Published 2019

Genetic Analysis of the Cardiac Methylome at Single Nucleotide Resolution in a Model of Human Cardiovascular Disease

by Johnson M.D., Mueller M., Adamowicz-Brice M., Collins M.J., Gellert P., Maratou K., Srivastava P.K., Rotival M., Butt S., Game L., Atanur S.S., Silver N., Norsworthy P.J., Langley S.R., Petretto E., Pravenec M., Aitman T.J.
Published 2018

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease

by Hubner N., Wallace C.A., Zimdahl H., Petretto E., Schulz H., Maciver F., Mueller M., Hummel O., Monti J., Zidek V., Musilova A., Kren V., Causton H., Game L., Born G., Schmidt S., M�ller A., Cook S.A., Kurtz T.W., Whittaker J., Pravenec M., Aitman T.J.
Published 2018

Ethnicity-Specific Skeletal Muscle Transcriptional Signatures and Their Relevance to Insulin Resistance in Singapore

by Tan A.L.M., Langley S.R., Tan C.F., Chai J.F., Khoo C.M., Leow M.K.-S., Khoo E.Y.H., Moreno-Moral A., Pravenec M., Rotival M., Sadananthan S.A., Velan S.S., Venkataraman K., Chong Y.S., Lee Y.S., Sim X., Stunkel W., Liu M.H., Tai E.S., Petretto E.
Published 2020

Wars2 is a determinant of angiogenesis

by Wang M., Sips P., Khin E., Rotival M., Sun X., Ahmed R., Widjaja A.A., Schafer S., Yusoff P., Choksi P.K., Ko N.S.J., Singh M.K., Epstein D., Guan Y., Houštěk J., Mracek T., Nuskova H., Mikell B., Tan J., Pesce F., Kolar F., Bottolo L., Mancini M., Hubner N., Pravenec M., Petretto E., Macrae C., Cook S.A.
Published 2019

Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass

by Petretto E., Sarwar R., Grieve I., Lu H., Kumaran M.K., Muckett P.J., Mangion J., Schroen B., Benson M., Punjabi P.P., Prasad S.K., Pennell D.J., Kiesewetter C., Tasheva E.S., Corpuz L.M., Webb M.D., Conrad G.W., Kurtz T.W., Kren V., Fischer J., Hubner N., Pinto Y.M., Pravenec M., Aitman T.J., Cook S.A.
Published 2018

Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function

by McDermott-Roe C., Ye J., Ahmed R., Sun X.-M., Serafín A., Ware J., Bottolo L., Muckett P., Cañas X., Zhang J., Rowe G.C., Buchan R., Lu H., Braithwaite A., Mancini M., Hauton D., Martí R., García-Arumí E., Hubner N., Jacob H., Serikawa T., Zidek V., Papousek F., Kolar F., Cardona M., Ruiz-Meana M., García-Dorado D., Comella J.X., Felkin L.E., Barton P.J.R., Arany Z., Pravenec M., Petretto E., Sanchis D., Cook S.A.
Published 2018

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

by Heinig M., Petretto E., Wallace C., Bottolo L., Rotival M., Lu H., Li Y., Sarwar R., Langley S.R., Bauerfeind A., Hummel O., Lee Y.-A., Paskas S., Rintisch C., Saar K., Cooper J., Buchan R., Gray E.E., Cyster J.G., Jeanette Erdmann, Hengstenberg C., Maouche S., Ouwehand W.H., Rice C.M., Samani N.J., Schunkert H., Goodall A.H., Schulz H., Roider H.G., Vingron M., Blankenberg S., M�nzel T., Zeller T., Szymczak S., Ziegler A., Tiret L., Smyth D.J., Pravenec M., Aitman T.J., Cambien F., Clayton D., Todd J.A., Hubner N., Cook S.A., Braund P., Gracey J., Krishnan U., Moore J.S., Nelson C.P., Pollard H., Attwood T., Crisp-Hihn A., Foad N., Jolley J., Lloyd-Jones H., Muir D., Murray E., O'Leary K., Rankin A., Sambrook J., Godfroy T., Brocheton J., Proust C., Schmitz G., Heimerl S., Lugauer I., Belz S., Gulde S., Linsel-Nitschke P., Sager H., Schroeder L., Lundmark P., Syvannen A.-C., Neudert J., Scholz M., Deloukas P., Gray E., Gwilliams R., Niblett D.
Published 2018