Understanding early molecular mechanisms of abnormal myelination in neurological conditions by characterising Ermin deficiency

by Oh, Sher Li, Ziaei, Amin, Tan, Liang Juin, Utami, Kagistia Hana, Pouladi, Mahmoud A., Langley, Sarah Raye
Published 2024

The habenula clock influences response to a stressor

by Basnakova, Adriana, Cheng, Ruey-Kuang, Chia, Joanne Shu Ming, D'Agostino, Giuseppe, Suryadi, Tan, Germaine Jia Hui, Langley, Sarah Raye, Jesuthasan, Suresh
Published 2022

Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease

by Tano, Vincent, Utami, Kagistia Hana, Nur Amirah Binte Mohammad Yusof, Bégin, Jocelyn, Tan, Willy Wei Li, Pouladi, Mahmoud A., Langley, Sarah Raye
Published 2023

Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease

by Fairley, Lauren H., Lai, Kei Onn, Wong, Jia Hui, Chong, Wei Jing, Vincent, Anselm Salvatore, D'Agostino, Giuseppe, Wu, Xiaoting, Naik, Roshan R., Jayaraman, Anusha, Langley, Sarah Raye, Ruedl, Christiane, Barron, Anna M.
Published 2023

Unbiased profiling of isogenic huntington disease hPSC-derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects

by Ziaei, Amin, Zeng, Ruizhu, Low, Donovan, Aminkeng, Folefac, Sobota, Radoslaw M., Ginhoux, Florent, Petretto, Enrico, Pouladi, Mahmoud A., Langley, Sarah Raye, Ooi, Jolene, Xu, Xiaohong, Utami, Kagistia H., Sim, Bernice, Huang, Yihui, Harmston, Nathan P., Tay, Yi Lin
Published 2019

Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease

by Bardile, Costanza Ferrari, Garcia-Miralles, Marta, Caron, Nicholas S., Rayan, Nirmala Arul, Langley, Sarah Raye, Harmston, Nathan, Rondelli, Ana Maria, Teo, Roy Tang Yi, Waltl, Sabine, Anderson, Lisa M., Bae, Han-Gyu, Jung, Sangyong, Williams, Anna, Prabhakar, Shyam, Petretto, Enrico, Hayden, Michael R., Pouladi, Mahmoud A.
Published 2020