Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes

by Tapsin, S, Sun, M, Shen, Y, Zhang, H, Lim, X.N, Susanto, T.T, Yang, S.L, Zeng, G.S, Lee, J, Lezhava, A, Ang, E.L, Zhang, L.H, Wang, Y, Zhao, H, Nagarajan, N, Wan, Y
Published 2020

Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723

by Sinha, S., Nge, C.-E., Leong, C.Y., Ng, V., Crasta, S., Alfatah, M., Goh, F., Low, K.-N., Zhang, H., Arumugam, P., Lezhava, A., Chen, S.L., Kanagasundaram, Y., Ng, S.B., Eisenhaber, F., Eisenhaber, B.
Published 2021

Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer

by Suzuki, Y, Ng, S.B, Chua, C, Leow, W.Q, Chng, J, Liu, S.Y, Ramnarayanan, K, Gan, A, Ho, D.L, Ten, R, Su, Y, Lezhava, A, Lai, J.H, Koh, D, Lim, K.H, Tan, P, Rozen, S.G, Tan, I.B
Published 2020

Identification and engineering of 32 membered antifungal macrolactone notonesomycins

by Goh, F., Zhang, M.M., Lim, T.R., Low, K.N., Nge, C.E., Heng, E., Yeo, W.L., Sirota, F.L., Crasta, S., Tan, Z., Ng, V., Leong, C.Y., Zhang, H., Lezhava, A., Chen, S.L., Hoon, S.S., Eisenhaber, F., Eisenhaber, B., Kanagasundaram, Y., Wong, F.T., Ng, S.B.
Published 2021

Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

by Chia, S, Low, J.-L, Zhang, X, Kwang, X.-L, Chong, F.-T, Sharma, A, Bertrand, D, Toh, S.Y, Leong, H.-S, Thangavelu, M.T, Hwang, J.S.G, Lim, K.-H, Skanthakumar, T, Tan, H.-K, Su, Y, Hui Choo, S, Hentze, H, Tan, I.B.H, Lezhava, A, Tan, P, Tan, D.S.W, Periyasamy, G, Koh, J.L.Y, Gopalakrishna Iyer, N, Dasgupta, R
Published 2020

VHL deficiency drives enhancer activation of oncogenes in clear cell renal cell carcinoma

by Yao, X, Tan, J, Lim, K.J, Koh, J, Ooi, W.F, Li, Z, Huang, D, Xing, M, Chan, Y.S, Qu, J.Z, Tay, S.T, Wijaya, G, Lam, Y.N, Hong, J.H, Lee-Lim, A.P, Guan, P, Ng, M.S.W, He, C.Z, Lin, J.S, Nandi, T, Qamra, A, Xu, C, Myint, S.S, Davies, J.O.J, Goh, J.Y, Loh, G, Tan, B.C, Rozen, S.G, Yu, Q, Tan, I.B.H, Cheng, C.W.S, Li, S, Chang, K.T.E, Tan, P.H, Silver, D.L, Lezhava, A, Steger, G, Hughes, J.R, Teh, B.T, Tan, P
Published 2020