Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy

by Madan, B, McDonald, M.J, Foxa, G.E, Diegel, C.R, Williams, B.O, Virshup, D.M
Published 2020

NOTUM is a potential pharmacodynamic biomarker of wnt pathway inhibition

by Madan, B, Ke, Z, Lei, Z.D, Oliver, F.A, Oshima, M, Lee, M.A, Rozen, S, Virshup, D.M
Published 2020

Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts

by Kabiri Z., Greicius G., Madan B., Biechele S., Zhong Z., Zaribafzadeh H., Edison, Aliyev J., Wu Y., Bunte R., Williams B.O., Rossant J., Virshup D.M.
Published 2020

Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia

by Hart, S., Goh, K.C., Novotny-Diermayr, V., Tan, Y.C., Madan, B., Amalini, C., Ong, L.C., Kheng, B., Cheong, A., Zhou, J., Chng, W.J., Wood, J.M.
Published 2014

TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome

by Ribi, S, Baumhoer, D, Lee, K, Edison, Teo, A.S, Madan, B, Zhang, K, Kohlmann, W.K, Yao, F, Lee, W.H, Hoi, Q, Cai, S, Woo, X.Y, Tan, P, Jundt, G, Smida, J, Nathrath, M, Sung, W.-K, Schiffman, J.D, Virshup, D.M, Hillmer, A.M
Published 2016

VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer

by Hart, S., Novotny-Diermayr, V., Goh, K.C., Williams, M., Tan, Y.C., Ong, L.C., Cheong, A., Ng, B.K., Amalini, C., Madan, B., Nagaraj, H., Jayaraman, R., Pasha, K.M., Ethirajulu, K., Chng, W.J., Mustafa, N., Goh, B.C., Benes, C., McDermott, U., Garnett, M., Dymock, B., Wood, J.M.
Published 2016