Human alpha cell transcriptomic signatures of types 1 and 2 diabetes highlight disease-specific dysfunction pathways

by Bosi, Emanuele, Marchetti, Piero, Rutter, Guy Allen, Eizirik, Decio Laks
Published 2023

Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

by Ghiasi, Seyed M., Marchetti, Piero, Piemonti, Lorenzo, Nielsen, Jens H., Porse, Bo T., Mandrup-Poulsen, Thomas, Rutter, Guy A.
Published 2024

Automated assessment of β-cell area and density per islet and patient using TMEM27 and BACE2 immunofluorescence staining in human pancreatic β-cells

by Rechsteiner, Markus P., Floros, Xenofon, Boehm, Bernhard O., Marselli, Lorella, Marchetti, Piero, Stoffel, Markus, Moch, Holger, Spinas, Giatgen A.
Published 2014

Persistent or transient human β cell dysfunction induced by metabolic stress : specific signatures and shared gene expression with type 2 diabetes

by Marselli, Lorella, Piron, Anthony, Suleiman, Mara, Colli, Maikel L., Yi, Xiaoyan, Khamis, Amna, Carrat, Gaelle R., Rutter, Guy A., Bugliani, Marco, Giusti, Laura, Ronci, Maurizio, Ibberson, Mark, Turatsinze, Jean-Valery, Boggi, Ugo, de Simone, Paolo, de Tata, Vincenzo, Lopes, Miguel, Nasteska, Daniela, de Luca, Carmela, Tesi, Marta, Bosi, Emanuele, Singh, Pratibha, Campani, Daniela, Schulte, Anke M., Solimena, Michele, Hecht, Peter, Rady, Brian, Bakaj, Ivona, Pocai, Alessandro, Norquay, Lisa, Thorens, Bernard, Canouil, Mickaël, Froguel, Philippe, Eizirik, Decio L., Cnop, Miriam, Marchetti, Piero
Published 2021