Long non-coding RNAs as key modulators of pancreatic β-cell mass and function

by López-Noriega, Livia, Rutter, Guy A.
Published 2021

New-onset type 1 diabetes and severe acute respiratory syndrome coronavirus 2 infection

by Anindya, Roy, Rutter, Guy A., Meur, Gargi
Published 2023

Optimized protocol for generating functional pancreatic insulin-secreting cells from human pluripotent stem cells

by Cherkaoui, Ines, Du, Qian, Egli, Dieter, Misra, Shivani, Rutter, Guy A.
Published 2024

Mechanisms of weight loss after obesity surgery

by Akalestou, Elina, Miras, Alexander D., Rutter, Guy A., le Roux, Carel W.
Published 2022

Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy

by So, Wing Yan, Liao, Yilie, Liu, Wai Nam, Rutter, Guy A., Han, Weiping
Published 2024

Covid-19 and diabetes : a complex bidirectional relationship

by Muniangi-Muhitu, Hermine, Akalestou, Elina, Salem, Victoria, Misra, Shivani, Oliver, Nicholas S., Rutter, Guy A.
Published 2021

Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice

by Akalestou, Elina, Lopez-Noriega, Livia, Christakis, Ioannis, Hu, Ming, Miras, Alexander D., Leclerc, Isabelle, Rutter, Guy A.
Published 2023

Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

by Ghiasi, Seyed M., Marchetti, Piero, Piemonti, Lorenzo, Nielsen, Jens H., Porse, Bo T., Mandrup-Poulsen, Thomas, Rutter, Guy A.
Published 2024

ZnT8 loss of function mutation increases resistance of human embryonic stem cell-derived beta cells to apoptosis in low zinc condition

by Sui, Lina, Du, Qian, Romer, Anthony, Su, Qi, Chabosseau, Pauline L., Xin, Yurong, Kim, Jinrang, Kleiner, Sandra, Rutter, Guy A., Egli, Dieter
Published 2023

Divergent acute versus prolonged pharmacological GLP-1R responses in adult β cell-specific β-arrestin 2 knockout mice

by Bitsi, Stavroula, El Eid, Liliane, Manchanda, Yusman, Oqua, Affiong I., Mohamed, Nimco, Hansen, Ben, Suba, Kinga, Rutter, Guy A., Salem, Victoria, Jones, Ben, Tomas, Alejandra
Published 2023

Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine-induced cell death

by Karsai, Maria, Zuellig, Richard A., Lehmann, Roger, Cuozzo, Federica, Nasteska, Daniela, Luca, Edlira, Hantel, Constanze, Hodson, David J., Spinas, Giatgen A., Rutter, Guy A., Gerber, Philipp A.
Published 2022

Autotaxin signaling facilitates β cell dedifferentiation and dysfunction induced by Sirtuin 3 deficiency

by Cao, Huanyi, Chung, Arthur C. K., Ming, Xing, Mao, Dandan, Lee, Heung Man, Cao, Xiaoyun, Rutter, Guy A., Chan, Juliana C. N., Tian, Xiao Yu, Kong, Alice P. S.
Published 2023

Impact of COVID-19 during pregnancy on placental pathology, maternal and neonatal outcome - a cross-sectional study on anemic term pregnant women from a tertiary care hospital in s...

by Surekha, M. V., Suneetha, N., Balakrishna, N., Putcha, Uday Kumar, Satyanarayana, K., Geddam, J. J. Babu, Sreenu, Pagidoju, Tulja, B., Mamidi, Raja Sriswan, Rutter, Guy A., Meur, Gargi
Published 2023

Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice

by Firth, George, Georgiadou, Eleni, Griffiths, Alexander, Amrahli, Maral, Kim, Jana, Yu, Zilin, Hu, Ming, Stewart, Theodora J., Leclerc, Isabelle, Okamoto, Haruka, Gomez, Daniel, Blower, Philip J., Rutter, Guy A.
Published 2023

Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes

by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu
Published 2022

Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

by Nguyen-Tu, Marie-Sophie, Harris, Joseph, Martinez-Sanchez, Aida, Chabosseau, Pauline, Hu, Ming, Georgiadou, Eleni, Pollard, Alice, Otero, Pablo, Lopez-Noriega, Livia, Leclerc, Isabelle, Sakamoto, Kei, Schmoll, Dieter, Smith, David M., Carling, David, Rutter, Guy A.
Published 2022

Molecular phenotyping of single pancreatic islet leader beta cells by "Flash-Seq"

by Chabosseau, Pauline, Yong, Fiona, Delgadillo-Silva, Luis F., Lee, Eun Young, Melhem, Rana, Li, Shiying, Gandhi, Nidhi, Wastin, Jules, Noriega, Livia Lopez, Leclerc, Isabelle, Ali, Yusuf, Hughes, Jing W., Sladek, Robert, Martinez-Sanchez, Aida, Rutter, Guy A.
Published 2023

An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study

by Slieker, Roderick C., Münch, Magnus, Donnelly, Louise A., Bouland, Gerard A., Dragan, Iulian, Kuznetsov, Dmitry, Elders, Petra J. M., Rutter, Guy A., Ibberson, Mark, Pearson, Ewan R., Hart, Leen M. 't, van de Wiel, Mark A., Beulens, Joline W. J.
Published 2024

A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice

by Amouyal, Chloé, Castel, Julien, Guay, Claudiane, Lacombe, Amélie, Denom, Jessica, Migrenne-Li, Stéphanie, Rouault, Christine, Marquet, Florian, Georgiadou, Eleni, Stylianides, Theodoros, Luquet, Serge, Le Stunff, Hervé, Scharfmann, Raphael, Clément, Karine, Rutter, Guy A., Taboureau, Olivier, Magnan, Christophe, Regazzi, Romano, Andreelli, Fabrizio
Published 2021

Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells

by Fang, Zijian, Chen, Shiqian, Manchanda, Yusman, Bitsi, Stavroula, Pickford, Philip, David, Alessia, Shchepinova, Maria M., Corrêa, Ivan R., Jr., Hodson, David J., Broichhagen, Johannes, Tate, Edward W., Reimann, Frank, Salem, Victoria, Rutter, Guy A., Tan, Tricia, Bloom, Stephen R., Tomas, Alejandra, Jones, Ben
Published 2021