Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice

Glucocorticoids produced by the adrenal cortex are essential for the maintenance of metabolic homeostasis. Glucocorticoid activation is catalysed by 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). Excess glucocorticoids are associated with insulin resistance and hyperglycaemia. A small number of stud...

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Main Authors: Akalestou, Elina, Lopez-Noriega, Livia, Christakis, Ioannis, Hu, Ming, Miras, Alexander D., Leclerc, Isabelle, Rutter, Guy A.
其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
格式: Article
語言:English
出版: 2023
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在線閱讀:https://hdl.handle.net/10356/171046
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機構: Nanyang Technological University
語言: English