Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice
Glucocorticoids produced by the adrenal cortex are essential for the maintenance of metabolic homeostasis. Glucocorticoid activation is catalysed by 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). Excess glucocorticoids are associated with insulin resistance and hyperglycaemia. A small number of stud...
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Main Authors: | Akalestou, Elina, Lopez-Noriega, Livia, Christakis, Ioannis, Hu, Ming, Miras, Alexander D., Leclerc, Isabelle, Rutter, Guy A. |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2023
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/171046 |
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Institution: | Nanyang Technological University |
Language: | English |
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