The IκB kinase inhibitor ACHP targets the STAT3 signaling pathway in human non-small cell lung carcinoma cells

by Lee, J.H., Mohan, C.D., Basappa, S., Rangappa, S., Chinnathambi, A., Alahmadi, T.A., Alharbi, S.A., Kumar, A.P., Sethi, G., Ahn, K.S., Rangappa, K.S.
Published 2021

Synthesis and characterization of novel 2-amino-chromene-nitriles that target Bcl-2 in acute myeloid leukemia cell lines

by Keerthy H.K., Garg M., Mohan C.D., Madan V., Kanojia D., Shobith R., Nanjundaswamy S., Mason D.J., Bender A., Basappa, Rangappa K.S., Koeffler H.P.
Published 2018

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

by Somu, C., Mohan, C.D., Ambekar, S., Dukanya, Rangappa, S., Baburajeev, C.P., Sukhorukov, A., Mishra, S., Shanmugam, M.K., Chinnathambi, A., Awad Alahmadi, T., Alharbi, S.A., Basappa, Rangappa, K.S.
Published 2021

Brusatol, a nrf2 inhibitor targets stat3 signaling cascade in head and neck squamous cell carcinoma

by Rangappa, K.S., Lee, J.H., Rangappa, S., Mohan, C.D., Basappa, Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysore, 570006, India., Sethi, G., Lin, Z.-X., Ahn, K.S.
Published 2021

Novel 1,3,4-oxadiazole targets STAT3 signaling to induce antitumor effect in lung cancer

by Malojirao, V.H., Girimanchanaika, S.S., Shanmugam, Muthu K., Sherapura, A., Dukanya, Metri, P.K., Vigneshwaran, V., Chinnathambi, A., Alharbi, S.A., Rangappa, S., Mohan, C.D., Basappa, Prabhakar, B.T., Rangappa, K.S.
Published 2021

Trisubstituted-imidazoles induce apoptosis in human breast cancer cells by targeting the oncogenic PI3K/Akt/mTOR signaling pathway

by Mohan C.D., Srinivasa V., Rangappa S., Mervin L., Mohan S., Paricharak S., Baday S., Li F., Shanmugam M.K., Chinnathambi A., Zayed M.E., Alharbi S.A., Bender A., Sethi G., Basappa, Rangappa K.S.
Published 2018

Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma

by Lee, J.H., Mohan, C.D., Deivasigamani, A., Jung, Y.Y., Rangappa, S., Basappa, S., Chinnathambi, A., Alahmadi, T.A., Alharbi, S.A., Garg, M., Lin, Z.-X., Rangappa, K.S., Sethi, G., Hui, K.M., Ahn, K.S.
Published 2021

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

by Nirvanappa A.C., Mohan C.D., Rangappa S., Ananda H., Sukhorukov A.Y., Shanmugam M.K., Sundaram M.S., Nayaka S.C., Girish K.S., Chinnathambi A., Zayed M.E., Alharbi S.A., Sethi G., Basappa, Rangappa K.S.
Published 2018

Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ

by Bharathkumar, H, Paricharak, S, Dinesh, K.R, Siveen, K.S, Fuchs, J.E, Rangappa, S, Mohan, C.D, Mohandas, N, Kumar, A.P, Sethi, G, Bender, A, Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Palace Road, Bangalore, 560001, India, Rangappa, K.S
Published 2020

Novel 1,3,4-oxadiazole induces anticancer activity by targeting NF-κB in hepatocellular carcinoma cells

by Mohan, C.D, Anilkumar, N.C, Rangappa, S, Shanmugam, M.K, Mishra, S, Chinnathambi, A, Alharbi, S.A, Bhattacharjee, A, Sethi, G, Kumar, A.P, Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India, Department of Studies in Organic Chemistry, University of Mysore, Mysore, India, Rangappa, K.S
Published 2020

N-substituted pyrido-1,4-Oxazin-3-ones induce apoptosis of hepatocellular carcinoma cells by targeting NF-?B signaling pathway

by Mohan, C.D, Bharathkumar, H, Dukanya, Department of Studies in Organic Chemistry, University of Mysore, Mysore, India, Rangappa, S, Shanmugam, M.K, Chinnathambi, A, Alharbi, S.A, Alahmadi, T.A, Bhattacharjee, A, Lobie, P.E, Deivasigamani, A, Hui, K.M, Sethi, G, Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India, Department of Studies in Organic Chemistry, University of Mysore, Mysore, India, Rangappa, K.S, Kumar, A.P
Published 2020