Enterovirus A71 and coxsackievirus A16 show different replication kinetics in human neuronal and non-neuronal cell lines

by Yogarajah, T., Ong, Kien Chai, Perera, D., Wong, Kum Thong
Published 2017

AIM2 Inflammasome-Mediated Pyroptosis in Enterovirus A71-Infected Neuronal Cells Restricts Viral Replication

by Yogarajah, T., Ong, Kien Chai, Perera, D., Wong, Kum Thong
Published 2017

RSAD2 and AIM2 modulate coxsackievirus A16 and enterovirus A71 replication in neuronal cells in different ways that may be associated with their 5' nontranslated regions

by Yogarajah, Thinesshwary, Ong, Kien Chai, Perera, David, Wong, Kumthong
Published 2018

RSAD2 and AIM2 Modulate Coxsackievirus A16 and Enterovirus A71 Replication in Neuronal Cells in Different Ways That May Be Associated with Their 5′ Nontranslated Regions

by Yogarajah, Thinesshwary, Ong, Kien Chai, Perera, David, Wong, Kum Thong
Published 2017

Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5

by Yu, Shu Pin, Ong, Kien Chai, Perera, David, Wong, Kum Thong
Published 2019

Formaldehyde-Inactivated Whole-Virus Vaccine Protects a Murine Model of Enterovirus 71 Encephalomyelitis against Disease

by Ong, Kien Chai, Devi, Shamala, Cardosa, Mary Jane, Wong, Kum Thong
Published 2010

Japanese encephalitis virus_Biological clones from a clinical isolate quasispecies show differing neurovirulence in vitro and in a mouse model

by Yu, Shu Pin, Ong, Kien Chai, Tan, Soon Hao, Perera, David, Wong, Kumthong
Published 2020

The medicinal mushroom Ganoderma neo-japonicum (Agaricomycetes) polysaccharide extract prevents obesity-induced diabetes in C57BL/6J mice

by Subramaniam, Sarasvathy, Ong, Kien Chai, Sabaratnam, Vikineswary, Chua, Kek Heng, Kuppusamy, Umah Rani
Published 2023

Japanese encephalitis virus: Biological clones from a clinical isolate quasispecies show differing neurovirulence in vitro and in a mouse model

by Yu, Shu Pin, Ong, Kien Chai, Tan, Soon Hao, Perera, David, Wong, Kum Thong
Published 2020

Natural-derived compounds and their mechanisms in potential autosomal dominant polycystic kidney disease (ADPKD) treatment

by Mahendran, Rhubaniya, Lim, Soo Kun, Ong, Kien Chai, Chua, Kek Heng, Chai, Hwa Chia
Published 2021

Myricetin derivative-rich fraction from Syzygium malaccenseprevents high-fat diet-induced obesity, glucose intolerance and oxidative stress in C57BL/6J mice

by Nallappan, Devi, Ong, Kien Chai, Palanisamy, Uma Devi, Chua, Kek Heng, Kuppusamy, Umah Rani
Published 2023

A novel orally infected hamster model for Coxsackievirus A16 hand-foot-and-mouth disease and encephalomyelitis

by Hooi, Yuan Teng, Ong, Kien Chai, Tan, Soon Hao, Perera, David, Wong, Kum Thong
Published 2020

Identification and characterization of neutralization epitopes at VP2 and VP1 of enterovirus A71

by Nik Nadia, Nik Mohd Nasir, Tan, Chee Wah, Ong, Kien Chai, Sam, I-Ching, Chan, Yoke Fun
Published 2018

Squamous epitheliotropism of Enterovirus A71 in human epidermis and oral mucosa

by Phyu, W.K., Ong, Kien Chai, Kong, C.K., Khalil, A.A., Ramanujam, T.M., Wong, Kum Thong
Published 2017

Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indolicidin and Ranalexin against Streptococcus pneumoniae

by Jindal, H.M., Zandi, K., Ong, Kien Chai, Velayuthan, Rukumani Devi, Rasid, S.M., Samudi, Chandramathi, Sekaran, Shamala Devi
Published 2017

Label-free surface-plasmon resonance fiber grating biosensor for Hand-foot-mouth disease (EV-A71) detection

by Udos, Waldo, Ooi, Cheong-Weng, Tan, Soon-Hao, Lim, Kok-Sing, Ee, Yen Jie, Ong, Kien Chai, Ahmad, Harith
Published 2021

In vitro antiviral activity of medicinal mushroom Ganoderma neo-japonicum Imazeki against enteroviruses that caused hand, foot and mouth disease

by Ang, W. X., Sarasvathy, S., Kuppusamy, Umah Rani, Sabaratnam, Vikineswary, Tan, S. H., Wong, Kum Thong, Perera, D., Ong, Kien Chai
Published 2021

Vaccine candidates generated by codon and codon pair deoptimization of enterovirus A71 protect against lethal challenge in mice

by Lee, Michelle Hui Pheng, Tan, Chee Wah, Tee, Han Kang, Ong, Kien Chai, Sam, I-Ching, Chan, Yoke Fun
Published 2021

Molecular mechanism of L-SP40 peptide and in vivo efficacy against EV-A71 in neonatal mice

by Lalani, Salima, Tan, Soon Hao, Tan, Kuan Onn *, Lim, Hui Xuan *, Ong, Kien Chai, Wong, Kum Thong, Poh, Chit Laa *
Published 2021

Molecular mechanism of L-SP40 peptide and in vivo efficacy against EV-A71 in neonatal mice

by Lalani, Salima, Tan, Soon Hao, Tan, Kuan Onn, Lim, Hui Xuan, Ong, Kien Chai, Wong, Kum Thong, Poh, Chit Laa
Published 2021