Molecular mechanism of L-SP40 peptide and in vivo efficacy against EV-A71 in neonatal mice

Aims: Enterovirus A71 (EV-A71) is an etiological agent of hand foot and mouth disease (HFMD) and has the potential to cause severe neurological infections in children. L-SP40 peptide was previously known to inhibit EV-A71 by prophylactic action. This study aimed to identify the mechanism of inhibiti...

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Main Authors: Lalani, Salima, Tan, Soon Hao, Tan, Kuan Onn *, Lim, Hui Xuan *, Ong, Kien Chai, Wong, Kum Thong, Poh, Chit Laa *
Format: Article
Published: Elsevier 2021
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Online Access:http://eprints.sunway.edu.my/1880/
http://doi.org/10.1016/j.lfs.2021.120097
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Institution: Sunway University