Upstream of N-Ras (Unr/CSDE1) Interacts with NCp7 and Gag, Modulating HIV-1 IRES-Mediated Translation Initiation

by Taha, Nedal, Zgheib, Sarwat, Sharma, Kamal Kant, Humbert, Nicolas, Boutant, Emmanuel, Didier, Pascal, Mely, Yves, Real, Eleonore
Published 2023

Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors

by Elgaher, Walid AM, Sharma, Kamal K, Haupenthal, Joerg, Saladini, Francesco, Pires, Manuel, Real, Eleonore, Mely, Yves, Hartmann, Rolf W
Published 2023

The nucleic acid chaperone activity of the HIV-1 Gag polyprotein is boosted by its cellular partner RPL7: a kinetic study

by Karnib, Hassan, Nadeem, Muhammad F, Humbert, Nicolas, Sharma, Kamal K, Grytsyk, Natalia, Tisné, Carine, Boutant, Emmanuel, Lequeu, Thiebault, Réal, Eleonore, Boudier, Christian, de Rocquigny, Hugues, Mély, Yves
Published 2020

(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Act...

by Humbert, Nicolas, Kovalenko, Lesia, Saladini, Francesco, Giannini, Alessia, Pires, Manuel, Botzanowski, Thomas, Cherenok, Sergiy, Boudier, Christian, Sharma, Kamal K, Real, Eleonore, Zaporozhets, Olga A, Cianferani, Sarah, Seguin-Devaux, Carole, Poggialini, Federica, Botta, Maurizio, Zazzi, Maurizio, Kalchenko, Vitaly, Mori, Mattia, Mely, Yves
Published 2023