Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase

by Xu, W, Lau, Y.H, Fischer, G, Tan, Y.S, Chattopadhyay, A, De La Roche, M, Hyvönen, M, Verma, C, Spring, D.R, Itzhaki, L.S
Published 2020

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein–Protein Interaction in Ovarian Cancer

by Wiedmann, M.M, Tan, Y.S, Wu, Y, Aibara, S, Xu, W, Sore, H.F, Verma, C.S, Itzhaki, L, Stewart, M, Brenton, J.D, Spring, D.R
Published 2020

Efficient development of stable and highly functionalised peptides targeting the CK2?/CK2? protein-protein interaction

by Iegre, J., Brear, P., Baker, D.J., Tan, Y.S., Atkinson, E.L., Sore, H.F., O'Donovan, D.H., Verma, C.S., Hyvönen, M., Spring, D.R.
Published 2021

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell

by Chattopadhyay, A, O'Connor, C.J, Zhang, F, Galvagnion, C, Galloway, W.R.J.D, Tan, Y.S, Stokes, J.E, Rahman, T, Verma, C, Spring, D.R, Itzhaki, L.S
Published 2020

Stapled peptides as a new technology to investigate protein-protein interactions in human platelets

by Iegre, J., Ahmed, N.S., Gaynord, J.S., Wu, Y., Herlihy, K.M., Tan, Y.S., Lopes-Pires, M.E., Jha, R., Lau, Y.H., Sore, H.F., Verma, C., O'Donovan, D.H., Pugh, N., Spring, D.R.
Published 2021

Functionalised staple linkages for modulating the cellular activity of stapled peptides

by Lau, Y.H., De Andrade, P., Quah, S.-T., Rossmann, M., Laraia, L., Sköld, N., Sum, T.J., Rowling, P.J.E., Joseph, T.L., Verma, C., Hyvönen, M., Itzhaki, L.S., Venkitaraman, A.R., Brown, C.J., Lane, D.P., Spring, D.R.
Published 2014