Mechanism of Oxygen Activation in a Flavin-Dependent Monooxygenase: A Nearly Barrierless Formation of C4a-Hydroperoxyflavin via Proton-Coupled Electron Transfer

بواسطة Surawit Visitsatthawong, Pirom Chenprakhon, Pimchai Chaiyen, Panida Surawatanawong
منشور في 2018

A Single-Site Mutation at Ser146 Expands the Reactivity of the Oxygenase Component of p-Hydroxyphenylacetate 3-Hydroxylase

بواسطة Taweesak Dhammaraj, Chatchadaporn Pinthong, Surawit Visitsatthawong, Chanakan Tongsook, Panida Surawatanawong, Pimchai Chaiyen
منشور في 2018

Proton-coupled electron transfer and adduct configuration are important for C4a-hydroperoxyflavin formation and stabilization in a flavoenzyme

بواسطة Thanyaporn Wongnate, Panida Surawatanawong, Surawit Visitsatthawong, Jeerus Sucharitakul, Nigel S. Scrutton, Pimchai Chaiyen
منشور في 2018

Mechanism-guided tunnel engineering to increase the efficiency of a flavin-dependent halogenase

بواسطة Kridsadakorn Prakinee, Aisaraphon Phintha, Surawit Visitsatthawong, Narin Lawan, Jeerus Sucharitakul, Chadaporn Kantiwiriyawanitch, Jiri Damborsky, Penchit Chitnumsub, Karl Heinz van Pée, Pimchai Chaiyen
منشور في 2022

Dissecting the low catalytic capability of flavin-dependent halogenases

بواسطة Aisaraphon Phintha, Kridsadakorn Prakinee, Aritsara Jaruwat, Narin Lawan, Surawit Visitsatthawong, Chadaporn Kantiwiriyawanitch, Warangkhana Songsungthong, Duangthip Trisrivirat, Pirom Chenprakhon, Adrian Mulholland, Karl Heinz van Pée, Penchit Chitnumsub, Pimchai Chaiyen
منشور في 2022

Resistance to the "last resort" antibiotic colistin: A single-zinc mechanism for phosphointermediate formation in MCR enzymes

بواسطة Emily Lythell, Reynier Suardíaz, Philip Hinchliffe, Chonnikan Hanpaibool, Surawit Visitsatthawong, A. Sofia F. Oliveira, A. Sofia F. Oliveira, Eric J.M. Lang, Panida Surawatanawong, Vannajan Sanghiran Lee, Thanyada Rungrotmongkol, Natalie Fey, James Spencer, Adrian J. Mulholland
منشور في 2020