Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model

by Lakshminarayana S.B., Freymond C., Fischli C., Yu J., Weber S., Goh A., Yeung B.K.S., Ho, Chi Lui Paul, Dartois V., Diagana T.T., Rottmann M., Blasco F.
Published 2016

PI4 kinase is a prophylactic but not radical curative target in Plasmodium vivax-type malaria parasites

by Zeeman, A.-M, Lakshminarayana, S.B, Van Der Werff, N, Klooster, E.J, Voorberg-Van Der Wel, A, Kondreddi, R.R, Bodenreider, C, Simon, O, Sauerwein, R, Yeung, B.K.S, Diagana, T.T, Kocken, C.H.M
Published 2020

The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites

by Dembele, L, Ang, X, Chavchich, M, Bonamy, G.M.C, Selva, J.J, Lim, M.Y.-X, Bodenreider, C, Yeung, B.K.S, Nosten, F, Russell, B.M, Edstein, M.D, Straimer, J, Fidock, D.A, Diagana, T.T, Bifani, P
Published 2020

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro

by Zeeman, A.-M, Van Amsterdam, S.M, McNamara, C.W, Voorberg-van Der Wel, A, Klooster, E.J, Van Den Berg, A, Remarque, E.J, Plouffe, D.M, Van Gemert, G.-J, Luty, A, Sauerwein, R, Gagaring, K, Borboa, R, Chen, Z, Kuhen, K, Glynne, R.J, Chatterjee, A.K, Nagle, A, Roland, J, Winzeler, E.A, Leroy, D, Campo, B, Diagana, T.T, Yeung, B.K.S, Thomas, A.W, Kocken, C.H.M
Published 2020

Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages

by Chua, A.C.Y., Ong, J.J.Y., Malleret, B., Suwanarusk, R., Kosaisavee, V., Zeeman, A.-M., Cooper, C.A., Tan, K.S.W., Zhang, R., Tan, B.H., Abas, S.N., Yip, A., Elliot, A., Joyner, C.J., Cho, J.S., Breyer, K., Baran, S., Lange, A., Maher, S.P., Nosten, F., Bodenreider, C., Yeung, B.K.S., Mazier, D., Galinski, M.R., Dereuddre-Bosquet, N., Le Grand, R., Kocken, C.H.M., Rénia, L., Kyle, D.E., Diagana, T.T., Snounou, G., Russell, B., Bifani, P.
Published 2021