Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm

by Meng, Qian-Fang, Tian, Rui, Long, Haiyi, Wu, Xianjia, Lai, Jialin, Zharkova, Olga, Wang, Jiong-Wei, Chen, Xiaoyuan, Rao, Lang
Published 2021

Lyophilization preserves the intrinsic cardioprotective activity of bioinspired cell-derived nanovesicles

by Neupane, Yub Raj, Huang, Chenyuan, Wang, Xiaoyuan, Chng, Wei Heng, Venkatesan, Gopalakrishnan, Zharkova, Olga, Wacker, Matthias Gerhard, Czarny, Bertrand, Storm, Gerrit, Wang, Jiong-Wei, Pastorin, Giorgia
Published 2021

Neutrophil Extracellular Trap Formation Is Dependent on Disease Activity in Systemic Lupus Erythematosus: Determination Using a Flow Cytometry-Based Assay

by Zharkova, Olga, Tay, Sen Hee, Lee, Hui Yin, Tripathi, Shubhita, Ong, Wei Yee, Lateef, Aisha, MacAry, Paul, Lime, Lina, Connolly, John Edward, Fairhurst, Anna-Marie
Published 2024

Lyophilization Preserves the Intrinsic Cardioprotective Activity of Bioinspired Cell-Derived Nanovesicles

by Neupane, Yub Raj, Huang, Chenyuan, Wang, Xiaoyuan, Chng, Wei Heng, Venkatesan, Gopalakrishnan, Zharkova, Olga, Wacker, Matthias Gerhard, Czarny, Bertrand, Storm, Gerrit, Wang, Jiong-Wei, Pastorin, Giorgia
Published 2021

A Flow Cytometry-Based Assay for High-Throughput Detection and Quantification of Neutrophil Extracellular Traps in Mixed Cell Populations

by Zharkova, Olga, Tay, Sen Hee, Lee, Hui Yin, Shubhita, Tripathi, Ong, Wei Yee, Lateef, Aisha, MacAry, Paul Anthony, Lim, Lina Hsiu Kim, Connolly, John Edward, Fairhurst, Anna-Marie
Published 2023

Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers

by CHONG SUET YEN, LEE CHOON KEONG, Huang, Chenyuan, Ou, Yi Hsuan, CHARLES, CHRISTOPHER JOHN, ARTHUR MARK RICHARDS, Neupane, Yub Raj, Pavon, Maria Vazquez, ZHARKOVA, OLGA, Pastorin,Giorgia, WANG JIONGWEI
Published 2019

Toll-like receptor 7 deficiency promotes survival and reduces adverse left ventricular remodelling after myocardial infarction

by de Kleijn, Dominique PV, Chong, Suet Yen, Wang, Xiaoyuan, Yatim, Siti Maryam JM, Fairhurst, Anna-Marie, Vernooij, Flora, Zharkova, Olga, Chan, Mark Y, Foo, Roger SY, Timmers, Leo, Lam, Carolyn SP, Wang, Jiong-Wei
Published 2021

Toll-Like Receptor 9 Deficiency Breaks Tolerance to RNA-Associated Antigens and Up-Regulates Toll-Like Receptor 7 Protein in Sle1 Mice

by Celhar, Teja, Yasuga, Hiroko, Lee, Hui Yin, Zharkova, Olga, Tripathi, Shubhita, Thornhill, Susannah I, Lu, Hao K, Au, Bijin, Lim, Lina HK, Thamboo, Thomas P, Akira, Shizuo, Wakeland, Edward K, Connolly, John E, Fairhurst, Anna-Marie
Published 2020

TLR7 protein expression in mild and severe lupus-prone models is regulated in a leukocyte, genetic, and IRAK4 dependent manner

by Celhar, Teja, Lu, Hao Kim, Benso, Lia, Rakhilina, Larissa, Lee, Hui Yin, Tripathi, Shubhita, Zharkova, Olga, Ong, Wei Yee, Yasuga, Hiroko, Au, Bijin, Marlier, Damien, Lim, Lina Hsiu Kim, Thamboo, Thomas Paulraj, Mudgett, John S., Mackey, Matthew F., Zaller, Dennis M., Connolly, John E., Fairhurst, Anna-Marie
Published 2019

TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner

by Celhar, Teja, Lu, Hao Kim, Benso, Lia, Rakhilina, Larissa, Lee, Hui Yin, Tripathi, Shubhita, Zharkova, Olga, Ong, Wei Yee, Yasuga, Hiroko, Au, Bijin, Marlier, Damien, Lim, Lina Hsiu Kim, Thamboo, Thomas Paulraj, Mudgett, John S, Mackey, Matthew F, Zaller, Dennis M, Connolly, John E, Fairhurst, Anna-Marie
Published 2020

Tissue factor cytoplasmic domain exacerbates post-infarct left ventricular remodeling via orchestrating cardiac inflammation and angiogenesis

by Chong, Suet Yen, Zharkova, Olga, Yatim, Siti Maryam JM, Wang, Xiaoyuan, Lim, Xiong Chang, Huang, Chenyuan, Tan, Chia Yee, Jiang, Jianming, Ye, Lei, Tan, Michelle Siying, Angeli, Veronique, Versteeg, Henri H, Dewerchin, Mieke, Carmeliet, Peter, Lam, Carolyn SP, Chan, Mark Y, de Kleijn, Dominique PV, Wang, Jiong-Wei
Published 2021

Platelet TLR7 is essential for the formation of platelet-neutrophil complexes and low-density neutrophils in lupus nephritis

by Tay, Sen Hee, Zharkova, Olga, Lee, Hui Yin, Toh, Michelle Min Xuan, Libau, Eshele Anak, Celhar, Teja, Narayanan, Sriram, Ahl, Patricia Jennifer, Ong, Wei Yee, Joseph, Craig, Lim, Jeffrey Chun Tatt, Wang, Lingzhi, Larbi, Anis, Liang, Shen, Lateef, Aisha, Akira, Shizuo, Ling, Lieng Hsi, Thamboo, Thomas Paulraj, Yeong, Joe Poh Seng, Lee, Bernett Teck Kwong, Edwards, Steven W, Wright, Helen L, MacAry, Paul Anthony, Connolly, John E, Fairhurst, Anna-Marie
Published 2024