THE INFLUENCE OF pH AND SURFACTANT IN DISSOLUTION MEDIUM ON THE DISSOLUTION OF MEFENAMIC ACID
Mefenamic acid is a weakly acidic and hydrophobic drug, therefore it has poor solubility in water, especially in acid condition. Dissolution test condition of mefenamic acid stated in USP 31 was actually irrelevant with gastrointestinal tract condition because of the high pH (pH 9,0) used. The purpo...
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| Format: | Final Project |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/10119 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |