PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO
The influence of various pepsin concentrations on the rate of degradation of lincomycin hydrocloride at pH 1.2 ; 2 and 3 has been studied in vitro. The rate of degradation was determined by monitoring the remaining concentration of lincomycin hydrocloride in the solution by high performance liquid c...
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id-itb.:11812004-11-23T16:00:33ZPENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO Sofia Pamudji, Jessie Farmakologi dan terapeutik Indonesia Theses INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/1181 The influence of various pepsin concentrations on the rate of degradation of lincomycin hydrocloride at pH 1.2 ; 2 and 3 has been studied in vitro. The rate of degradation was determined by monitoring the remaining concentration of lincomycin hydrocloride in the solution by high performance liquid chromatography and microbiology. It was shown that high performance liquid chromatography gave a better result than microbiology method. The kinetic of degradation test showed that lincomycin hydrocloride at pH 1.2 and 3 was not influenced by pepsin, while at pH 2 the rate of degradation of lincomycin hydrocloride was increased. text |
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Farmakologi dan terapeutik |
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Farmakologi dan terapeutik Sofia Pamudji, Jessie PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO |
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The influence of various pepsin concentrations on the rate of degradation of lincomycin hydrocloride at pH 1.2 ; 2 and 3 has been studied in vitro. The rate of degradation was determined by monitoring the remaining concentration of lincomycin hydrocloride in the solution by high performance liquid chromatography and microbiology. It was shown that high performance liquid chromatography gave a better result than microbiology method. The kinetic of degradation test showed that lincomycin hydrocloride at pH 1.2 and 3 was not influenced by pepsin, while at pH 2 the rate of degradation of lincomycin hydrocloride was increased. |
format |
Theses |
author |
Sofia Pamudji, Jessie |
author_facet |
Sofia Pamudji, Jessie |
author_sort |
Sofia Pamudji, Jessie |
title |
PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO |
title_short |
PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO |
title_full |
PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO |
title_fullStr |
PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO |
title_full_unstemmed |
PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO |
title_sort |
pengaruh pepsin terhadap kecepatan penguraian linkomisin hidroklorida secara in vitro |
url |
https://digilib.itb.ac.id/gdl/view/1181 |
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1820662889719005184 |