PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO

The influence of various pepsin concentrations on the rate of degradation of lincomycin hydrocloride at pH 1.2 ; 2 and 3 has been studied in vitro. The rate of degradation was determined by monitoring the remaining concentration of lincomycin hydrocloride in the solution by high performance liquid c...

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Main Author: Sofia Pamudji, Jessie
Format: Theses
Language:Indonesia
Subjects:
Online Access:https://digilib.itb.ac.id/gdl/view/1181
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Institution: Institut Teknologi Bandung
Language: Indonesia
id id-itb.:1181
spelling id-itb.:11812004-11-23T16:00:33ZPENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO Sofia Pamudji, Jessie Farmakologi dan terapeutik Indonesia Theses INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/1181 The influence of various pepsin concentrations on the rate of degradation of lincomycin hydrocloride at pH 1.2 ; 2 and 3 has been studied in vitro. The rate of degradation was determined by monitoring the remaining concentration of lincomycin hydrocloride in the solution by high performance liquid chromatography and microbiology. It was shown that high performance liquid chromatography gave a better result than microbiology method. The kinetic of degradation test showed that lincomycin hydrocloride at pH 1.2 and 3 was not influenced by pepsin, while at pH 2 the rate of degradation of lincomycin hydrocloride was increased. text
institution Institut Teknologi Bandung
building Institut Teknologi Bandung Library
continent Asia
country Indonesia
Indonesia
content_provider Institut Teknologi Bandung
collection Digital ITB
language Indonesia
topic Farmakologi dan terapeutik
spellingShingle Farmakologi dan terapeutik
Sofia Pamudji, Jessie
PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO
description The influence of various pepsin concentrations on the rate of degradation of lincomycin hydrocloride at pH 1.2 ; 2 and 3 has been studied in vitro. The rate of degradation was determined by monitoring the remaining concentration of lincomycin hydrocloride in the solution by high performance liquid chromatography and microbiology. It was shown that high performance liquid chromatography gave a better result than microbiology method. The kinetic of degradation test showed that lincomycin hydrocloride at pH 1.2 and 3 was not influenced by pepsin, while at pH 2 the rate of degradation of lincomycin hydrocloride was increased.
format Theses
author Sofia Pamudji, Jessie
author_facet Sofia Pamudji, Jessie
author_sort Sofia Pamudji, Jessie
title PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO
title_short PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO
title_full PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO
title_fullStr PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO
title_full_unstemmed PENGARUH PEPSIN TERHADAP KECEPATAN PENGURAIAN LINKOMISIN HIDROKLORIDA SECARA IN VITRO
title_sort pengaruh pepsin terhadap kecepatan penguraian linkomisin hidroklorida secara in vitro
url https://digilib.itb.ac.id/gdl/view/1181
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