UJI EFEK ANTI IMPLANTASI POST KOITUS EKSTRAK KERING BATANG BRATAWALI DAN EKSTRAK KENTAL RIMPANG TEMULAWAK TERHADAP TIKUS HAMIL

The dry extract of Bratawali (Tinospora tuberculata Beumee) stems and the soft extract of Temulawak (Curcuma Xanthorrhiza Roxb) rhizomes were tested for antifertility activity in female albinorats (Sister strain). Oral administrations of these extracts at a dose of 5 gram/kg body weight to pregnant...

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Bibliographic Details
Main Author: ARITONANG, HAMONANGAN
Format: Theses
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/2078
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Institution: Institut Teknologi Bandung
Language: Indonesia
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Summary:The dry extract of Bratawali (Tinospora tuberculata Beumee) stems and the soft extract of Temulawak (Curcuma Xanthorrhiza Roxb) rhizomes were tested for antifertility activity in female albinorats (Sister strain). Oral administrations of these extracts at a dose of 5 gram/kg body weight to pregnant rats from day 1 to 5 days and 1 to 7 days causes significant inhibition of inplantion (P with 0,01). However when administrated on days 6-9 and days 7-9 of gentation their effects were not pronounced. The result indicated that both Temulawak and Barawali possess anti implantation activity during the early stages of pregnancy (1st to 5th day and 1st to 7th day). Moreover Bratawali showed approximately 75 % foetal loss. Whereas Temulawak did not affect the proportion implantation sites.