SINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA
7-Carboxy chroman-4-one, an important intermediate in the preparation of 3-benzylidene 7-carboxy chroman-4- ones which have antiinflammatory and analgesic activities, has been synthetized through new route of reaction using glycerol and m-cresol as starting materials. Glycerol was dehydrated by pota...
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id-itb.:20812004-11-02T10:03:29ZSINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA RIVAI, HARRIZUL Indonesia Theses INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/2081 7-Carboxy chroman-4-one, an important intermediate in the preparation of 3-benzylidene 7-carboxy chroman-4- ones which have antiinflammatory and analgesic activities, has been synthetized through new route of reaction using glycerol and m-cresol as starting materials. Glycerol was dehydrated by potassium bisulfate to yield acrolein. Acrolein was condensed with m-cresol in benzene in the presence of sodium ethoxide as catalyst to yield 3-(3-methylphenoxy) propionaldehyde which can be cyclisized to form 7-carboxy chroman-4-one after previous oxidation. 5-Carboxy chroman-4-one was also obtained as a byproduct. text |
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7-Carboxy chroman-4-one, an important intermediate in the preparation of 3-benzylidene 7-carboxy chroman-4- ones which have antiinflammatory and analgesic activities, has been synthetized through new route of reaction using glycerol and m-cresol as starting materials. Glycerol was dehydrated by potassium bisulfate to yield acrolein. Acrolein was condensed with m-cresol in benzene in the presence of sodium ethoxide as catalyst to yield 3-(3-methylphenoxy) propionaldehyde which can be cyclisized to form 7-carboxy chroman-4-one after previous oxidation. 5-Carboxy chroman-4-one was also obtained as a byproduct. |
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Theses |
author |
RIVAI, HARRIZUL |
spellingShingle |
RIVAI, HARRIZUL SINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA |
author_facet |
RIVAI, HARRIZUL |
author_sort |
RIVAI, HARRIZUL |
title |
SINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA |
title_short |
SINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA |
title_full |
SINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA |
title_fullStr |
SINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA |
title_full_unstemmed |
SINTESIS 7. KARBOKSI KROMAN .4.0N DARI GLISEROL DAN M . KRESOL SEBAGAI BAHAN PEMULA |
title_sort |
sintesis 7. karboksi kroman .4.0n dari gliserol dan m . kresol sebagai bahan pemula |
url |
https://digilib.itb.ac.id/gdl/view/2081 |
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